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Page 1
QClus: a droplet filtering algorithm for enhanced snRNA-seq data quality in challenging samples.
Schmauch E, Ojanen J, Galani K, Jalkanen J, Harju K, Hollmén M, Kokki H, Gunn J, Halonen J, Hartikainen J, Kiviniemi T, Tavi P, Kaikkonen MU, Kellis M, Linna-Kuosmanen S. Schmauch E, et al. Among authors: kaikkonen mu. Nucleic Acids Res. 2025 Jan 7;53(1):gkae1145. doi: 10.1093/nar/gkae1145. Nucleic Acids Res. 2025. PMID: 39656909 Free PMC article.
Secreted protein profiling of human aortic smooth muscle cells identifies vascular disease associations.
Aherrahrou R, Baig F, Theofilatos K, Lue D, Beele A, Örd T, Kaikkonen MU, Aherrahrou Z, Cheng Q, Ghosh S, Karnewar S, Karnewar V, Finn A, Owens GK, Joner M, Mayr M, Civelek M. Aherrahrou R, et al. Among authors: kaikkonen mu. medRxiv [Preprint]. 2023 Nov 10:2023.11.10.23298351. doi: 10.1101/2023.11.10.23298351. medRxiv. 2023. Update in: Arterioscler Thromb Vasc Biol. 2024 Apr;44(4):898-914. doi: 10.1161/ATVBAHA.123.320274 PMID: 37986932 Free PMC article. Updated. Preprint.
Novel Lipid Long Intervening Noncoding RNA, Oligodendrocyte Maturation-Associated Long Intergenic Noncoding RNA, Regulates the Liver Steatosis Gene Stearoyl-Coenzyme A Desaturase As an Enhancer RNA.
Benhammou JN, Ko A, Alvarez M, Kaikkonen MU, Rankin C, Garske KM, Padua D, Bhagat Y, Kaminska D, Kärjä V, Pihlajamäki J, Pisegna JR, Pajukanta P. Benhammou JN, et al. Among authors: kaikkonen mu. Hepatol Commun. 2019 Aug 14;3(10):1356-1372. doi: 10.1002/hep4.1413. eCollection 2019 Oct. Hepatol Commun. 2019. PMID: 31592021 Free PMC article.
GLS2 links glutamine metabolism and atherosclerosis by remodeling artery walls.
Murcy F, Borowczyk C, Gourion-Arsiquaud S, Torrino S, Ouahrouche N, Barouillet T, Dussaud S, Couralet M, Vaillant N, Merlin J, Berquand A, Kaikkonen MU, McClelland RL, Tressel W, Stein J, Thorp EB, Bertero T, Barbry P, Bailly-Maitre B, Gautier EL, Karjalainen MK, Kettunen J, Duca L, Shea S, Yvan-Charvet L. Murcy F, et al. Among authors: kaikkonen mu. Nat Cardiovasc Res. 2024 Dec;3(12):1454-1467. doi: 10.1038/s44161-024-00566-1. Epub 2024 Nov 19. Nat Cardiovasc Res. 2024. PMID: 39562782
Progression of herpesvirus infection remodels mitochondrial organization and metabolism.
Leclerc S, Gupta A, Ruokolainen V, Chen JH, Kunnas K, Ekman AA, Niskanen H, Belevich I, Vihinen H, Turkki P, Perez-Berna AJ, Kapishnikov S, Mäntylä E, Harkiolaki M, Dufour E, Hytönen V, Pereiro E, McEnroe T, Fahy K, Kaikkonen MU, Jokitalo E, Larabell CA, Weinhardt V, Mattola S, Aho V, Vihinen-Ranta M. Leclerc S, et al. Among authors: kaikkonen mu. PLoS Pathog. 2024 Apr 15;20(4):e1011829. doi: 10.1371/journal.ppat.1011829. eCollection 2024 Apr. PLoS Pathog. 2024. PMID: 38620036 Free PMC article.
Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation.
Cuartero S, Weiss FD, Dharmalingam G, Guo Y, Ing-Simmons E, Masella S, Robles-Rebollo I, Xiao X, Wang YF, Barozzi I, Djeghloul D, Amano MT, Niskanen H, Petretto E, Dowell RD, Tachibana K, Kaikkonen MU, Nasmyth KA, Lenhard B, Natoli G, Fisher AG, Merkenschlager M. Cuartero S, et al. Among authors: kaikkonen mu. Nat Immunol. 2018 Sep;19(9):932-941. doi: 10.1038/s41590-018-0184-1. Epub 2018 Aug 20. Nat Immunol. 2018. PMID: 30127433 Free PMC article.
Integration of single cell omics with biobank data discovers trans effects of SREBF1 abdominal obesity risk variants on adipocyte expression of more than 100 genes.
Sukhatme MG, Kar A, Arasu UT, Lee SHT, Alvarez M, Garske KM, Gelev KZ, Rajkumar S, Das SS, Kaminska D, Männistö V, Peltoniemi H, Heinonen S, Säiläkivi U, Saarinen T, Juuti A, Pietiläinen KH, Pihlajamäki J, Kaikkonen MU, Pajukanta P. Sukhatme MG, et al. Among authors: kaikkonen mu. medRxiv [Preprint]. 2024 Nov 23:2024.11.22.24317804. doi: 10.1101/2024.11.22.24317804. medRxiv. 2024. PMID: 39606332 Free PMC article. Preprint.
Colchicine promotes atherosclerotic plaque stability independently of inflammation.
Li W, Lin A, Hutton M, Dhaliwal H, Nadel J, Rodor J, Tumanov S, Örd T, Hadden M, Mokry M, Mol BM, Pasterkamp G, Padula MP, Geczy CL, Ramaswamy Y, Sluimer JC, Kaikkonen MU, Stocker R, Baker AH, Fisher EA, Patel S, Misra A. Li W, et al. Among authors: kaikkonen mu. bioRxiv [Preprint]. 2023 Oct 3:2023.10.03.560632. doi: 10.1101/2023.10.03.560632. bioRxiv. 2023. PMID: 37873248 Free PMC article. Preprint.
Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia.
Korvenlaita N, Gómez-Budia M, Scoyni F, Pistono C, Giudice L, Eamen S, Loppi S, de Sande AH, Huremagic B, Bouvy-Liivrand M, Heinäniemi M, Kaikkonen MU, Cheng L, Hill AF, Kanninen KM, Jenster GW, van Royen ME, Ramiro L, Montaner J, Batkova T, Mikulik R, Giugno R, Jolkkonen J, Korhonen P, Malm T. Korvenlaita N, et al. Among authors: kaikkonen mu. J Extracell Vesicles. 2023 Jan;12(1):e12297. doi: 10.1002/jev2.12297. J Extracell Vesicles. 2023. PMID: 36594832 Free PMC article.
124 results