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Dietary protein defends lean mass and maintains the metabolic benefits of glucagon receptor agonism in mice.
Lopes T, Hope DC, Ramos-Pittol JM, Curtis A, Shrewsbury JV, Davies I, Zhou Z, Sardini A, Minnion JS, Dormann D, Bewick GA, Murphy KG, Carling D, Bloom SR, Tan TM, Owen BM. Lopes T, et al. Among authors: ramos pittol jm. Mol Metab. 2024 Nov;89:102024. doi: 10.1016/j.molmet.2024.102024. Epub 2024 Sep 3. Mol Metab. 2024. PMID: 39236784 Free PMC article.
Dax1 modulates ERα-dependent hypothalamic estrogen sensing in female mice.
Ramos-Pittol JM, Fernandes-Freitas I, Milona A, Manchishi SM, Rainbow K, Lam BYH, Tadross JA, Beucher A, Colledge WH, Cebola I, Murphy KG, Miguel-Aliaga I, Yeo GSH, Dhillo WS, Owen BM. Ramos-Pittol JM, et al. Nat Commun. 2023 May 29;14(1):3076. doi: 10.1038/s41467-023-38618-y. Nat Commun. 2023. PMID: 37248237 Free PMC article.
mTORC1 Crosstalk With Stress Granules in Aging and Age-Related Diseases.
Cadena Sandoval M, Heberle AM, Rehbein U, Barile C, Ramos Pittol JM, Thedieck K. Cadena Sandoval M, et al. Among authors: ramos pittol jm. Front Aging. 2021 Oct 13;2:761333. doi: 10.3389/fragi.2021.761333. eCollection 2021. Front Aging. 2021. PMID: 35822040 Free PMC article. Review.
Fine-Tuning Cardiac Insulin-Like Growth Factor 1 Receptor Signaling to Promote Health and Longevity.
Abdellatif M, Trummer-Herbst V, Heberle AM, Humnig A, Pendl T, Durand S, Cerrato G, Hofer SJ, Islam M, Voglhuber J, Ramos Pittol JM, Kepp O, Hoefler G, Schmidt A, Rainer PP, Scherr D, von Lewinski D, Bisping E, McMullen JR, Diwan A, Eisenberg T, Madeo F, Thedieck K, Kroemer G, Sedej S. Abdellatif M, et al. Among authors: ramos pittol jm. Circulation. 2022 Jun 21;145(25):1853-1866. doi: 10.1161/CIRCULATIONAHA.122.059863. Epub 2022 May 26. Circulation. 2022. PMID: 35616058 Free PMC article.
The Pseudokinase TRIB3 Negatively Regulates the HER2 Receptor Pathway and Is a Biomarker of Good Prognosis in Luminal Breast Cancer.
Orea-Soufi A, Castillo-Lluva S, Salvador-Tormo N, Martín-Cabrera P, Recuero S, Gabicagogeascoa E, Moreno-Valladares M, Mendiburu-Eliçabe M, Blanco-Gómez A, Ramos-Pittol JM, García-Taboada E, Ocaña A, Cimas FJ, Matheu A, Álvarez-López I, Velasco G, Lorente M. Orea-Soufi A, et al. Among authors: ramos pittol jm. Cancers (Basel). 2021 Oct 22;13(21):5307. doi: 10.3390/cancers13215307. Cancers (Basel). 2021. PMID: 34771470 Free PMC article.
Ablation of liver Fxr results in an increased colonic mucus barrier in mice.
Ijssennagger N, van Rooijen KS, Magnúsdóttir S, Ramos Pittol JM, Willemsen ECL, de Zoete MR, Baars MJD, Stege PB, Colliva C, Pellicciari R, Youssef SA, de Bruin A, Vercoulen Y, Kuipers F, van Mil SWC. Ijssennagger N, et al. Among authors: ramos pittol jm. JHEP Rep. 2021 Aug 4;3(5):100344. doi: 10.1016/j.jhepr.2021.100344. eCollection 2021 Oct. JHEP Rep. 2021. PMID: 34604725 Free PMC article.
G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling.
Prentzell MT, Rehbein U, Cadena Sandoval M, De Meulemeester AS, Baumeister R, Brohée L, Berdel B, Bockwoldt M, Carroll B, Chowdhury SR, von Deimling A, Demetriades C, Figlia G; Genomics England Research Consortium; de Araujo MEG, Heberle AM, Heiland I, Holzwarth B, Huber LA, Jaworski J, Kedra M, Kern K, Kopach A, Korolchuk VI, van 't Land-Kuper I, Macias M, Nellist M, Palm W, Pusch S, Ramos Pittol JM, Reil M, Reintjes A, Reuter F, Sampson JR, Scheldeman C, Siekierska A, Stefan E, Teleman AA, Thomas LE, Torres-Quesada O, Trump S, West HD, de Witte P, Woltering S, Yordanov TE, Zmorzynska J, Opitz CA, Thedieck K. Prentzell MT, et al. Among authors: ramos pittol jm. Cell. 2021 Feb 4;184(3):655-674.e27. doi: 10.1016/j.cell.2020.12.024. Epub 2021 Jan 25. Cell. 2021. PMID: 33497611 Free PMC article.
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