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Microcin MccI47 selectively inhibits enteric bacteria and reduces carbapenem-resistant Klebsiella pneumoniae colonization in vivo when administered via an engineered live biotherapeutic.
Mortzfeld BM, Palmer JD, Bhattarai SK, Dupre HL, Mercado-Lubio R, Silby MW, Bang C, McCormick BA, Bucci V. Mortzfeld BM, et al. Among authors: bhattarai sk. Gut Microbes. 2022 Jan-Dec;14(1):2127633. doi: 10.1080/19490976.2022.2127633. Gut Microbes. 2022. PMID: 36175830 Free PMC article.
Commensal antimicrobial resistance mediates microbiome resilience to antibiotic disruption.
Bhattarai SK, Du M, Zeamer AL, M Morzfeld B, Kellogg TD, Firat K, Benjamin A, Bean JM, Zimmerman M, Mardi G, Vilbrun SC, Walsh KF, Fitzgerald DW, Glickman MS, Bucci V. Bhattarai SK, et al. Sci Transl Med. 2024 Jan 17;16(730):eadi9711. doi: 10.1126/scitranslmed.adi9711. Epub 2024 Jan 17. Sci Transl Med. 2024. PMID: 38232140 Free PMC article.
Microbiota encoded fatty-acid metabolism expands tuft cells to protect tissues homeostasis during Clostridioides difficile infection in the large intestine.
Kellogg TD, Ceglia S, Mortzfeld BM, Zeamer AL, Foley SE, Ward DV, Bhattarai SK, McCormick BA, Reboldi A, Bucci V. Kellogg TD, et al. Among authors: bhattarai sk. bioRxiv [Preprint]. 2024 Jan 31:2024.01.29.574039. doi: 10.1101/2024.01.29.574039. bioRxiv. 2024. PMID: 38352546 Free PMC article. Preprint.
Commensal consortia decolonize Enterobacteriaceae via ecological control.
Furuichi M, Kawaguchi T, Pust MM, Yasuma-Mitobe K, Plichta DR, Hasegawa N, Ohya T, Bhattarai SK, Sasajima S, Aoto Y, Tuganbaev T, Yaginuma M, Ueda M, Okahashi N, Amafuji K, Kiridoshi Y, Sugita K, Stražar M, Avila-Pacheco J, Pierce K, Clish CB, Skelly AN, Hattori M, Nakamoto N, Caballero S, Norman JM, Olle B, Tanoue T, Suda W, Arita M, Bucci V, Atarashi K, Xavier RJ, Honda K. Furuichi M, et al. Among authors: bhattarai sk. Nature. 2024 Sep;633(8031):878-886. doi: 10.1038/s41586-024-07960-6. Epub 2024 Sep 18. Nature. 2024. PMID: 39294375 Free PMC article.
25 results