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The psychoplastogens ibogaminalog and ibogainalog induce antidepressant-like activity in naïve and depressed mice by mechanisms involving 5-HT2A receptor activation and serotonergic transmission.
Arias HR, Rudin D, Luethi D, Valenta J, Leśniak A, Czartoryska Z, Olejarz-Maciej A, Doroz-Płonka A, Manetti D, De Deurwaerdère P, Romanelli MN, Handzlik J, Liechti ME, Chagraoui A. Arias HR, et al. Among authors: luethi d. Prog Neuropsychopharmacol Biol Psychiatry. 2024 Dec 9;136:111217. doi: 10.1016/j.pnpbp.2024.111217. Online ahead of print. Prog Neuropsychopharmacol Biol Psychiatry. 2024. PMID: 39662723
Structural basis of organic cation transporter-3 inhibition.
Khanppnavar B, Maier J, Herborg F, Gradisch R, Lazzarin E, Luethi D, Yang JW, Qi C, Holy M, Jäntsch K, Kudlacek O, Schicker K, Werge T, Gether U, Stockner T, Korkhov VM, Sitte HH. Khanppnavar B, et al. Among authors: luethi d. Nat Commun. 2022 Nov 7;13(1):6714. doi: 10.1038/s41467-022-34284-8. Nat Commun. 2022. PMID: 36344565 Free PMC article.
Pharmacological profile of methylphenidate-based designer drugs.
Luethi D, Kaeser PJ, Brandt SD, Krähenbühl S, Hoener MC, Liechti ME. Luethi D, et al. Neuropharmacology. 2018 May 15;134(Pt A):133-140. doi: 10.1016/j.neuropharm.2017.08.020. Epub 2017 Aug 18. Neuropharmacology. 2018. PMID: 28823611 Free article.
44 results