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Discovery and Development of an Advanced Lead for the Treatment of African Trypanosomiasis.
Ilbeigi K, Mabille D, Matheeussen A, Hendrickx R, Claes M, Van Reet N, Anthonissen R, Hulpia F, Lin C, Maes L, Regnault C, Whitfield P, Roy R, Ungogo MA, Sterckx YG, De Winter H, Mertens B, Bundschuh M, De Koning HP, Van Calenbergh S, Caljon G. Ilbeigi K, et al. Among authors: sterckx yg. ACS Infect Dis. 2024 Dec 12. doi: 10.1021/acsinfecdis.4c00472. Online ahead of print. ACS Infect Dis. 2024. PMID: 39665421
Biophysical analysis of the membrane-proximal Venus Flytrap domain of ESAG4 receptor-like adenylate cyclase from Trypanosoma brucei.
Alves DO, Geens R, da Silva Arruda HR, Jennen L, Corthaut S, Wuyts E, de Andrade GC, Prosdocimi F, Cordeiro Y, Pires JR, Vieira LR, de Oliveira GAP, Sterckx YG, Salmon D. Alves DO, et al. Among authors: sterckx yg. Mol Biochem Parasitol. 2024 Dec;260:111653. doi: 10.1016/j.molbiopara.2024.111653. Epub 2024 Oct 22. Mol Biochem Parasitol. 2024. PMID: 39447762 Free article.
Mass spectrometry-complemented molecular modeling predicts the interaction interface for a camelid single-domain antibody targeting the Plasmodium falciparum circumsporozoite protein's C-terminal domain.
Opuni KFM, Ruß M, Geens R, Vocht L, Wielendaele PV, Debuy C, Sterckx YG, Glocker MO. Opuni KFM, et al. Among authors: sterckx yg. Comput Struct Biotechnol J. 2024 Aug 28;23:3300-3314. doi: 10.1016/j.csbj.2024.08.023. eCollection 2024 Dec. Comput Struct Biotechnol J. 2024. PMID: 39296809 Free PMC article.
Long-term hematopoietic stem cells trigger quiescence in Leishmania parasites.
Dirkx L, Van Acker SI, Nicolaes Y, Cunha JLR, Ahmad R, Hendrickx R, Caljon B, Imamura H, Ebo DG, Jeffares DC, Sterckx YG, Maes L, Hendrickx S, Caljon G. Dirkx L, et al. Among authors: sterckx yg. PLoS Pathog. 2024 Apr 24;20(4):e1012181. doi: 10.1371/journal.ppat.1012181. eCollection 2024 Apr. PLoS Pathog. 2024. PMID: 38656959 Free PMC article.
A high-throughput target-based screening approach for the identification and assessment of Mycobacterium tuberculosis mycothione reductase inhibitors.
Smiejkowska N, Oorts L, Van Calster K, De Vooght L, Geens R, Mattelaer H-P, Augustyns K, Strelkov SV, Lamprecht D, Temmerman K, Sterckx YG-J, Cappoen D, Cos P. Smiejkowska N, et al. Among authors: sterckx yg j. Microbiol Spectr. 2024 Mar 5;12(3):e0372323. doi: 10.1128/spectrum.03723-23. Epub 2024 Feb 5. Microbiol Spectr. 2024. PMID: 38315026 Free PMC article.
A Fijivirus Major Viroplasm Protein Shows RNA-Stimulated ATPase Activity by Adopting Pentameric and Hexameric Assemblies of Dimers.
Llauger G, Melero R, Monti D, Sycz G, Huck-Iriart C, Cerutti ML, Klinke S, Mikkelsen E, Tijman A, Arranz R, Alfonso V, Arellano SM, Goldbaum FA, Sterckx YGJ, Carazo JM, Kaufman SB, Dans PD, Del Vas M, Otero LH. Llauger G, et al. Among authors: sterckx ygj. mBio. 2023 Apr 25;14(2):e0002323. doi: 10.1128/mbio.00023-23. Epub 2023 Feb 14. mBio. 2023. PMID: 36786587 Free PMC article.
41 results