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Page 1
Transposable element exonization generates a reservoir of evolving and functional protein isoforms.
Arribas YA, Baudon B, Rotival M, Suárez G, Bonté PE, Casas V, Roubert A, Klein P, Bonnin E, Mchich B, Legoix P, Baulande S, Sadacca B, Diharce J, Waterfall JJ, Etchebest C, Carrascal M, Goudot C, Quintana-Murci L, Burbage M, Merlotti A, Amigorena S. Arribas YA, et al. Among authors: sadacca b. Cell. 2024 Dec 26;187(26):7603-7620.e22. doi: 10.1016/j.cell.2024.11.011. Epub 2024 Dec 11. Cell. 2024. PMID: 39667937 Free article.
Noncanonical splicing junctions between exons and transposable elements represent a source of immunogenic recurrent neo-antigens in patients with lung cancer.
Merlotti A, Sadacca B, Arribas YA, Ngoma M, Burbage M, Goudot C, Houy A, Rocañín-Arjó A, Lalanne A, Seguin-Givelet A, Lefevre M, Heurtebise-Chrétien S, Baudon B, Oliveira G, Loew D, Carrascal M, Wu CJ, Lantz O, Stern MH, Girard N, Waterfall JJ, Amigorena S. Merlotti A, et al. Among authors: sadacca b. Sci Immunol. 2023 Feb 3;8(80):eabm6359. doi: 10.1126/sciimmunol.abm6359. Epub 2023 Feb 3. Sci Immunol. 2023. PMID: 36735774
Epigenetically controlled tumor antigens derived from splice junctions between exons and transposable elements.
Burbage M, Rocañín-Arjó A, Baudon B, Arribas YA, Merlotti A, Rookhuizen DC, Heurtebise-Chrétien S, Ye M, Houy A, Burgdorf N, Suarez G, Gros M, Sadacca B, Carrascal M, Garmilla A, Bohec M, Baulande S, Lombard B, Loew D, Waterfall JJ, Stern MH, Goudot C, Amigorena S. Burbage M, et al. Among authors: sadacca b. Sci Immunol. 2023 Feb 3;8(80):eabm6360. doi: 10.1126/sciimmunol.abm6360. Epub 2023 Feb 3. Sci Immunol. 2023. PMID: 36735776
ERG transcription factors have a splicing regulatory function involving RBFOX2 that is altered in the EWS-FLI1 oncogenic fusion.
Saulnier O, Guedri-Idjouadiene K, Aynaud MM, Chakraborty A, Bruyr J, Pineau J, O'Grady T, Mirabeau O, Grossetête S, Galvan B, Claes M, Al Oula Hassoun Z, Sadacca B, Laud K, Zaïdi S, Surdez D, Baulande S, Rambout X, Tirode F, Dutertre M, Delattre O, Dequiedt F. Saulnier O, et al. Among authors: sadacca b. Nucleic Acids Res. 2021 May 21;49(9):5038-5056. doi: 10.1093/nar/gkab305. Nucleic Acids Res. 2021. PMID: 34009296 Free PMC article.
Evolution of synchronous female bilateral breast cancers and response to treatment.
Hamy AS, Abécassis J, Driouch K, Darrigues L, Vandenbogaert M, Laurent C, Zaccarini F, Sadacca B, Delomenie M, Laas E, Mariani O, Lam T, Grandal B, Laé M, Bieche I, Vacher S, Pierga JY, Brain E, Vallot C, Hotton J, Richer W, Rocha D, Tariq Z, Becette V, Meseure D, Lesage L, Vincent-Salomon A, Filmann N, Furlanetto J, Loibl S, Dumas E, Waterfall JJ, Reyal F. Hamy AS, et al. Among authors: sadacca b. Nat Med. 2023 Mar;29(3):646-655. doi: 10.1038/s41591-023-02216-8. Epub 2023 Mar 6. Nat Med. 2023. PMID: 36879128 Free PMC article.
No evidence for TSLP pathway activity in human breast cancer.
Ghirelli C, Sadacca B, Reyal F, Zollinger R, Michea P, Sirven P, Pattarini L, Martínez-Cingolani C, Guillot-Delost M, Nicolas A, Scholer-Dahirel A, Soumelis V. Ghirelli C, et al. Among authors: sadacca b. Oncoimmunology. 2016 May 9;5(8):e1178438. doi: 10.1080/2162402X.2016.1178438. eCollection 2016 Aug. Oncoimmunology. 2016. PMID: 27622057 Free PMC article.
27 results