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A STAT3-STING-IFN axis controls the metastatic spread of small cell lung cancer.
Guanizo AC, Luong Q, Jayasekara WSN, de Geus ED, Inampudi C, Xue VS, Chen J, de Weerd NA, Matthews AY, Gantier MP, Balic JJ, Arulananda S, Garama DJ, Hertzog PJ, Ganju V, Watkins DN, Cain JE, Gough DJ. Guanizo AC, et al. Among authors: watkins dn. Nat Immunol. 2024 Dec;25(12):2259-2269. doi: 10.1038/s41590-024-02014-5. Epub 2024 Nov 21. Nat Immunol. 2024. PMID: 39572642
Ligand-dependent hedgehog signaling maintains an undifferentiated, malignant osteosarcoma phenotype.
Vaghjiani VG, Cochrane CR, Jayasekara WSN, Chong WC, Szczepny A, Kumar B, Martelotto LG, McCaw A, Carey K, Kansara M, Thomas DM, Walkley C, Mudge S, Gough DJ, Downie PA, Peacock CD, Matsui W, Watkins DN, Cain JE. Vaghjiani VG, et al. Among authors: watkins dn. Oncogene. 2023 Nov;42(47):3529-3541. doi: 10.1038/s41388-023-02864-7. Epub 2023 Oct 16. Oncogene. 2023. PMID: 37845394 Free PMC article.
SILAC kinase screen identifies potential MASTL substrates.
Marzec KA, Rogers S, McCloy R, Parker BL, James DE, Watkins DN, Burgess A. Marzec KA, et al. Among authors: watkins dn. Sci Rep. 2022 Jun 22;12(1):10568. doi: 10.1038/s41598-022-14933-0. Sci Rep. 2022. PMID: 35732702 Free PMC article.
Deletion of kif3a in CK19 positive cells leads to primary cilia loss, biliary cell proliferation and cystic liver lesions in TAA-treated mice.
Chen J, Cheng NC, Boland JA, Liu K, Kench JG, Watkins DN, Ferreira-Gonzalez S, Forbes SJ, McCaughan GW. Chen J, et al. Among authors: watkins dn. Biochim Biophys Acta Mol Basis Dis. 2022 Apr 1;1868(4):166335. doi: 10.1016/j.bbadis.2021.166335. Epub 2021 Dec 30. Biochim Biophys Acta Mol Basis Dis. 2022. PMID: 34973373 Free article.
Trp53 and Rb1 regulate autophagy and ligand-dependent Hedgehog signaling.
Cochrane CR, Vaghjiani V, Szczepny A, Jayasekara WSN, Gonzalez-Rajal A, Kikuchi K, McCaughan GW, Burgess A, Gough DJ, Watkins DN, Cain JE. Cochrane CR, et al. Among authors: watkins dn. J Clin Invest. 2020 Aug 3;130(8):4006-4018. doi: 10.1172/JCI132513. J Clin Invest. 2020. PMID: 32568216 Free PMC article.
127 results