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Page 1
Canonical androgen response element motifs are tumor suppressive regulatory elements in the prostate.
Chen X, Augello MA, Liu D, Lin K, Hakansson A, Sjöström M, Khani F, Deonarine LD, Liu Y, Travascio-Green J, Wu J, Chan UI, Owiredu J, Loda M, Feng FY, Robinson BD, Davicioni E, Sboner A, Barbieri CE. Chen X, et al. Among authors: sboner a. Nat Commun. 2024 Dec 13;15(1):10675. doi: 10.1038/s41467-024-53734-z. Nat Commun. 2024. PMID: 39672812 Free PMC article.
CHD1 Loss Alters AR Binding at Lineage-Specific Enhancers and Modulates Distinct Transcriptional Programs to Drive Prostate Tumorigenesis.
Augello MA, Liu D, Deonarine LD, Robinson BD, Huang D, Stelloo S, Blattner M, Doane AS, Wong EWP, Chen Y, Rubin MA, Beltran H, Elemento O, Bergman AM, Zwart W, Sboner A, Dephoure N, Barbieri CE. Augello MA, et al. Among authors: sboner a. Cancer Cell. 2019 Apr 15;35(4):603-617.e8. doi: 10.1016/j.ccell.2019.03.001. Epub 2019 Mar 28. Cancer Cell. 2019. PMID: 30930119 Free PMC article.
FOXA1 mutations alter pioneering activity, differentiation and prostate cancer phenotypes.
Adams EJ, Karthaus WR, Hoover E, Liu D, Gruet A, Zhang Z, Cho H, DiLoreto R, Chhangawala S, Liu Y, Watson PA, Davicioni E, Sboner A, Barbieri CE, Bose R, Leslie CS, Sawyers CL. Adams EJ, et al. Among authors: sboner a. Nature. 2019 Jul;571(7765):408-412. doi: 10.1038/s41586-019-1318-9. Epub 2019 Jun 26. Nature. 2019. PMID: 31243370 Free PMC article.
Temporal evolution of cellular heterogeneity during the progression to advanced AR-negative prostate cancer.
Brady NJ, Bagadion AM, Singh R, Conteduca V, Van Emmenis L, Arceci E, Pakula H, Carelli R, Khani F, Bakht M, Sigouros M, Bareja R, Sboner A, Elemento O, Tagawa S, Nanus DM, Loda M, Beltran H, Robinson B, Rickman DS. Brady NJ, et al. Among authors: sboner a. Nat Commun. 2021 Jun 7;12(1):3372. doi: 10.1038/s41467-021-23780-y. Nat Commun. 2021. PMID: 34099734 Free PMC article.
Reshaping of the androgen-driven chromatin landscape in normal prostate cells by early cancer drivers and effect on therapeutic sensitivity.
Grbesa I, Augello MA, Liu D, McNally DR, Gaffney CD, Huang D, Lin K, Ivenitsky D, Goueli R, Robinson BD, Khani F, Deonarine LD, Blattner M, Elemento O, Davicioni E, Sboner A, Barbieri CE. Grbesa I, et al. Among authors: sboner a. Cell Rep. 2021 Sep 7;36(10):109625. doi: 10.1016/j.celrep.2021.109625. Cell Rep. 2021. PMID: 34496233 Free PMC article.
G3BP1 inhibits Cul3SPOP to amplify AR signaling and promote prostate cancer.
Mukhopadhyay C, Yang C, Xu L, Liu D, Wang Y, Huang D, Deonarine LD, Cyrta J, Davicioni E, Sboner A, Robinson BD, Chinnaiyan AM, Rubin MA, Barbieri CE, Zhou P. Mukhopadhyay C, et al. Among authors: sboner a. Nat Commun. 2021 Nov 18;12(1):6662. doi: 10.1038/s41467-021-27024-x. Nat Commun. 2021. PMID: 34795264 Free PMC article.
SPOP Mutation Drives Prostate Tumorigenesis In Vivo through Coordinate Regulation of PI3K/mTOR and AR Signaling.
Blattner M, Liu D, Robinson BD, Huang D, Poliakov A, Gao D, Nataraj S, Deonarine LD, Augello MA, Sailer V, Ponnala L, Ittmann M, Chinnaiyan AM, Sboner A, Chen Y, Rubin MA, Barbieri CE. Blattner M, et al. Among authors: sboner a. Cancer Cell. 2017 Mar 13;31(3):436-451. doi: 10.1016/j.ccell.2017.02.004. Cancer Cell. 2017. PMID: 28292441 Free PMC article.
Patient derived organoids to model rare prostate cancer phenotypes.
Puca L, Bareja R, Prandi D, Shaw R, Benelli M, Karthaus WR, Hess J, Sigouros M, Donoghue A, Kossai M, Gao D, Cyrta J, Sailer V, Vosoughi A, Pauli C, Churakova Y, Cheung C, Deonarine LD, McNary TJ, Rosati R, Tagawa ST, Nanus DM, Mosquera JM, Sawyers CL, Chen Y, Inghirami G, Rao RA, Grandori C, Elemento O, Sboner A, Demichelis F, Rubin MA, Beltran H. Puca L, et al. Among authors: sboner a. Nat Commun. 2018 Jun 19;9(1):2404. doi: 10.1038/s41467-018-04495-z. Nat Commun. 2018. PMID: 29921838 Free PMC article.
N-Myc-mediated epigenetic reprogramming drives lineage plasticity in advanced prostate cancer.
Berger A, Brady NJ, Bareja R, Robinson B, Conteduca V, Augello MA, Puca L, Ahmed A, Dardenne E, Lu X, Hwang I, Bagadion AM, Sboner A, Elemento O, Paik J, Yu J, Barbieri CE, Dephoure N, Beltran H, Rickman DS. Berger A, et al. Among authors: sboner a. J Clin Invest. 2019 Jul 1;129(9):3924-3940. doi: 10.1172/JCI127961. J Clin Invest. 2019. PMID: 31260412 Free PMC article.
182 results