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434 results

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Page 1
In vivo evolution of env in SHIV-AD8EO-infected rhesus macaques after AAV-vectored delivery of eCD4-Ig.
O'Hagan D, Shandilya S, Hopkins LJ, Hahn PA, Fuchs SP, Martinez-Navio JM, Alpert MD, Gardner MR, Desrosiers RC, Gao G, Lifson JD, Farzan M, Ardeshir A, Martins MA. O'Hagan D, et al. Among authors: lifson jd. Mol Ther. 2024 Dec 12:S1525-0016(24)00814-1. doi: 10.1016/j.ymthe.2024.12.015. Online ahead of print. Mol Ther. 2024. PMID: 39673132 Free article.
Adeno-associated viral delivery of Env-specific antibodies prevents SIV rebound after discontinuing antiretroviral therapy.
Klenchin VA, Clark NM, Keles NK, Capuano S, Mason R, Gao G, Broman A, Kose E, Immonen TT, Fennessey CM, Keele BF, Lifson JD, Roederer M, Gardner MR, Evans DT. Klenchin VA, et al. Among authors: lifson jd. bioRxiv [Preprint]. 2024 Jun 3:2024.05.30.593694. doi: 10.1101/2024.05.30.593694. bioRxiv. 2024. PMID: 38895320 Free PMC article. Preprint.
Microglia and macrophages alterations in the CNS during acute SIV infection: a single-cell analysis in rhesus macaques.
Xu X, Niu M, Lamberty BG, Emanuel K, Trease AJ, Tabassum M, Lifson JD, Fox HS. Xu X, et al. Among authors: lifson jd. bioRxiv [Preprint]. 2024 Apr 4:2024.04.04.588047. doi: 10.1101/2024.04.04.588047. bioRxiv. 2024. Update in: PLoS Pathog. 2024 Sep 16;20(9):e1012168. doi: 10.1371/journal.ppat.1012168 PMID: 38617282 Free PMC article. Updated. Preprint.
Potent antibody-dependent cellular cytotoxicity of a V2-specific antibody is not sufficient for protection of macaques against SIV challenge.
Grunst MW, Gil HM, Grandea AG 3rd, Snow BJ, Andrabi R, Nedellec R, Burton I, Clark NM, Janaka SK, Keles NK, Moriarty RV, Weiler AM, Capuano S 3rd, Fennessey CM, Friedrich TC, O'Connor SL, O'Connor DH, Broman AT, Keele BF, Lifson JD, Hangartner L, Burton DR, Evans DT. Grunst MW, et al. Among authors: lifson jd. PLoS Pathog. 2024 Jan 22;20(1):e1011819. doi: 10.1371/journal.ppat.1011819. eCollection 2024 Jan. PLoS Pathog. 2024. PMID: 38252675 Free PMC article.
The Impact of SIV-Induced Immunodeficiency on SARS-CoV-2 Disease, Viral Dynamics, and Antiviral Immune Response in a Nonhuman Primate Model of Coinfection.
Melton A, Rowe LA, Penney T, Krzykwa C, Goff K, Scheuermann SE, Melton HJ, Williams K, Golden N, Green KM, Smith B, Russell-Lodrigue K, Dufour JP, Doyle-Meyers LA, Schiro F, Aye PP, Lifson JD, Beddingfield BJ, Blair RV, Bohm RP, Kolls JK, Rappaport J, Hoxie JA, Maness NJ. Melton A, et al. Among authors: lifson jd. Viruses. 2024 Jul 21;16(7):1173. doi: 10.3390/v16071173. Viruses. 2024. PMID: 39066335 Free PMC article.
Dual blockade of IL-10 and PD-1 leads to control of SIV viral rebound following analytical treatment interruption.
Pereira Ribeiro S, Strongin Z, Soudeyns H, Ten-Caten F, Ghneim K, Pacheco Sanchez G, Xavier de Medeiros G, Del Rio Estrada PM, Pelletier AN, Hoang T, Nguyen K, Harper J, Jean S, Wallace C, Balderas R, Lifson JD, Raghunathan G, Rimmer E, Pastuskova C, Wu G, Micci L, Ribeiro RM, Chan CN, Estes JD, Silvestri G, Gorman DM, Howell BJ, Hazuda DJ, Paiardini M, Sekaly RP. Pereira Ribeiro S, et al. Among authors: lifson jd. Nat Immunol. 2024 Oct;25(10):1900-1912. doi: 10.1038/s41590-024-01952-4. Epub 2024 Sep 12. Nat Immunol. 2024. PMID: 39266691 Free PMC article.
CD4 T cell Responses in the CNS during SIV infection.
Elizaldi SR, Verma A, Ma ZM, Ott S, Rajasundaram D, Cottrell ML, Kashuba ADM, Ambrose Z, Lifson JD, Morrison JH, Iyer SS. Elizaldi SR, et al. Among authors: lifson jd. bioRxiv [Preprint]. 2023 Aug 25:2023.08.24.554055. doi: 10.1101/2023.08.24.554055. bioRxiv. 2023. Update in: PLoS Pathog. 2023 Dec 7;19(12):e1011844. doi: 10.1371/journal.ppat.1011844 PMID: 37662237 Free PMC article. Updated. Preprint.
The Impact of SIV-Induced Immunodeficiency on Clinical Manifestation, Immune Response, and Viral Dynamics in SARS-CoV-2 Coinfection.
Melton A, Rowe LA, Penney T, Krzykwa C, Goff K, Scheuermann S, Melton HJ, Williams K, Golden N, Green KM, Smith B, Russell-Lodrigue K, Dufour JP, Doyle-Meyers LA, Schiro F, Aye PP, Lifson JD, Beddingfield BJ, Blair RV, Bohm RP, Kolls JK, Rappaport J, Hoxie JA, Maness NJ. Melton A, et al. Among authors: lifson jd. bioRxiv [Preprint]. 2023 Nov 16:2023.11.15.567132. doi: 10.1101/2023.11.15.567132. bioRxiv. 2023. Update in: Viruses. 2024 Jul 21;16(7):1173. doi: 10.3390/v16071173 PMID: 38014096 Free PMC article. Updated. Preprint.
434 results