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29 results

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Exploration of (R)-[11C]YH168 as a PET tracer for imaging monoacylglycerol lipase in the brain: from mice to non-human primates.
He Y, Zheng M, Gu J, Reichert L, Trimborn J, Zhang H, Keller C, Crosby M, Collin L, Heer D, Pavlovic A, Topp A, Wittwer MB, Grether U, Gobbi L, Schibli R, Huang Y, Mu L. He Y, et al. Among authors: topp a. Eur J Nucl Med Mol Imaging. 2024 Dec 14. doi: 10.1007/s00259-024-07013-0. Online ahead of print. Eur J Nucl Med Mol Imaging. 2024. PMID: 39673602
Identification of (R)-[18F]YH134 for Monoacylglycerol Lipase Neuroimaging and Exploration of Its Use for Central Nervous System and Peripheral Drug Development.
He Y, Krämer SD, Grether U, Wittwer MB, Collin L, Kuhn B, Topp A, Heer D, O'Hara F, Honer M, Pavlovic A, Richter H, Ritter M, Rombach D, Keller C, Gobbi L, Mu L. He Y, et al. Among authors: topp a. J Nucl Med. 2024 Feb 1;65(2):300-305. doi: 10.2967/jnumed.123.266426. J Nucl Med. 2024. PMID: 38164615
Structure-Guided Discovery of cis-Hexahydro-pyrido-oxazinones as Reversible, Drug-like Monoacylglycerol Lipase Inhibitors.
Kuhn B, Ritter M, Hornsperger B, Bell C, Kocer B, Rombach D, Lutz MDR, Gobbi L, Kuratli M, Bartelmus C, Bürkler M, Koller R, Tosatti P, Ruf I, Guerard M, Pavlovic A, Stephanus J, O'Hara F, Wetzl D, Saal W, Stihle M, Roth D, Hug M, Huber S, Heer D, Kroll C, Topp A, Schneider M, Gertsch J, Glasmacher S, van der Stelt M, Martella A, Wittwer MB, Collin L, Benz J, Richter H, Grether U. Kuhn B, et al. Among authors: topp a. J Med Chem. 2024 Oct 24;67(20):18448-18464. doi: 10.1021/acs.jmedchem.4c01769. Epub 2024 Oct 3. J Med Chem. 2024. PMID: 39360636
Development of a Highly Selective NanoBRET Probe to Assess MAGL Inhibition in Live Cells.
Gazzi T, Brennecke B, Olikauskas V, Hochstrasser R, Wang H, Keen Chao S, Atz K, Mostinski Y, Topp A, Heer D, Kaufmann I, Ritter M, Gobbi L, Hornsperger B, Wagner B, Richter H, O'Hara F, Wittwer MB, Jul Hansen D, Collin L, Kuhn B, Benz J, Grether U, Nazaré M. Gazzi T, et al. Among authors: topp a. Chembiochem. 2024 Nov 28:e202400704. doi: 10.1002/cbic.202400704. Online ahead of print. Chembiochem. 2024. PMID: 39607084
Detection and Characterization of Alongshan Virus in Ticks and Tick Saliva from Lower Saxony, Germany with Serological Evidence for Viral Transmission to Game and Domestic Animals.
Ebert CL, Söder L, Kubinski M, Glanz J, Gregersen E, Dümmer K, Grund D, Wöhler AS, Könenkamp L, Liebig K, Knoll S, Hellhammer F, Topp AK, Becher P, Springer A, Strube C, Nagel-Kohl U, Nordhoff M, Steffen I, Bauer BU, Ganter M, Feige K, Becker SC, Boelke M. Ebert CL, et al. Among authors: topp ak. Microorganisms. 2023 Feb 21;11(3):543. doi: 10.3390/microorganisms11030543. Microorganisms. 2023. PMID: 36985117 Free PMC article.
29 results