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The zymogenic form of SARS-CoV-2 main protease: A discrete target for drug discovery.
Novotný P, Humpolíčková J, Nováková V, Stanchev S, Stříšovský K, Zgarbová M, Weber J, Kryštůfek R, Starková J, Hradilek M, Moravcová A, Günterová J, Bach K, Majer P, Konvalinka J, Majerová T. Novotný P, et al. Among authors: krystufek r. J Biol Chem. 2024 Dec 13:108079. doi: 10.1016/j.jbc.2024.108079. Online ahead of print. J Biol Chem. 2024. PMID: 39675720 Free article.
Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery.
Kryštůfek R, Šácha P, Starková J, Brynda J, Hradilek M, Tloušt'ová E, Grzymska J, Rut W, Boucher MJ, Drąg M, Majer P, Hájek M, Řezáčová P, Madhani HD, Craik CS, Konvalinka J. Kryštůfek R, et al. J Med Chem. 2021 May 27;64(10):6706-6719. doi: 10.1021/acs.jmedchem.0c02177. Epub 2021 May 18. J Med Chem. 2021. PMID: 34006103 Free PMC article.
Inhibitor-GCPII Interaction: Selective and Robust System for Targeting Cancer Cells with Structurally Diverse Nanoparticles.
Neburkova J, Sedlak F, Zackova Suchanova J, Kostka L, Sacha P, Subr V, Etrych T, Simon P, Barinkova J, Krystufek R, Spanielova H, Forstova J, Konvalinka J, Cigler P. Neburkova J, et al. Among authors: krystufek r. Mol Pharm. 2018 Aug 6;15(8):2932-2945. doi: 10.1021/acs.molpharmaceut.7b00889. Epub 2018 Feb 13. Mol Pharm. 2018. PMID: 29389139