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Page 1
GWAS highlights the neuronal contribution to multiple sclerosis susceptibility.
Zeng L, Atlas K, Lama T; International Multiple Sclerosis Genetics Consortium; Chitnis T, Weiner H, Wang G, Fujita M, Zipp F, Taga M, Kiryluk K, De Jager PL. Zeng L, et al. Among authors: de jager pl. medRxiv [Preprint]. 2024 Dec 5:2024.12.04.24318500. doi: 10.1101/2024.12.04.24318500. medRxiv. 2024. PMID: 39677438 Free PMC article. Preprint.
No evidence for shared genetic basis of common variants in multiple sclerosis and amyotrophic lateral sclerosis.
Goris A, van Setten J, Diekstra F, Ripke S, Patsopoulos NA, Sawcer SJ; International Multiple Sclerosis Genetics Consortium; van Es M; Australia and New Zealand MS Genetics Consortium; Andersen PM, Melki J, Meininger V, Hardiman O, Landers JE, Brown RH Jr, Shatunov A, Leigh N, Al-Chalabi A, Shaw CE, Traynor BJ, Chiò A, Restagno G, Mora G, Ophoff RA, Oksenberg JR, Van Damme P, Compston A, Robberecht W, Dubois B, van den Berg LH, De Jager PL, Veldink JH, de Bakker PI. Goris A, et al. Among authors: de jager pl, de bakker pi. Hum Mol Genet. 2014 Apr 1;23(7):1916-22. doi: 10.1093/hmg/ddt574. Epub 2013 Nov 13. Hum Mol Genet. 2014. PMID: 24234648 Free PMC article.
A single-nucleus transcriptome-wide association study implicates novel genes in depression pathogenesis.
Zeng L, Fujita M, Gao Z, White CC, Green GS, Habib N, Menon V, Bennett DA, Boyle PA, Klein HU, De Jager PL. Zeng L, et al. Among authors: de jager pl. medRxiv [Preprint]. 2023 Mar 29:2023.03.27.23286844. doi: 10.1101/2023.03.27.23286844. medRxiv. 2023. Update in: Biol Psychiatry. 2024 Jul 1;96(1):34-43. doi: 10.1016/j.biopsych.2023.12.012 PMID: 37034737 Free PMC article. Updated. Preprint.
Genome-wide studies define new genetic mechanisms of IgA vasculitis.
Liu L, Zhu L, Monteiro-Martins S, Griffin A, Vlahos LJ, Fujita M, Berrouet C, Zanoni F, Marasa M, Zhang JY, Zhou XJ, Caliskan Y, Akchurin O, Al-Akash S, Jankauskiene A, Bodria M, Chishti A, Esposito C, Esposito V, Claes D, Tesar V, Davis TK, Samsonov D, Kaminska D, Hryszko T, Zaza G, Flynn JT, Iorember F, Lugani F, Rizk D, Julian BA, Hidalgo G, Kallash M, Biancone L, Amoroso A, Bono L, Mani LY, Vogt B, Lin F, Sreedharan R, Weng P, Ranch D, Xiao N, Quiroga A, Matar RB, Rheault MN, Wenderfer S, Selewski D, Lundberg S, Silva C, Mason S, Mahan JD, Vasylyeva TL, Mucha K, Foroncewicz B, Pączek L, Florczak M, Olszewska M, Gradzińska A, Szczepańska M, Machura E, Badeński A, Krakowczyk H, Sikora P, Kwella N, Miklaszewska M, Drożdż D, Zaniew M, Pawlaczyk K, SiniewiczLuzeńczyk K, Bomback AS, Appel GB, Izzi C, Scolari F, Materna-Kiryluk A, Mizerska-Wasiak M, Berthelot L, Pillebout E, Monteiro RC, Novak J, Green TJ, Smoyer WE, Hastings MC, Wyatt RJ, Nelson R, Martin J, González-Gay MA, De Jager PL, Köttgen A, Califano A, Gharavi AG, Zhang H, Kiryluk K. Liu L, et al. Among authors: de jager pl. medRxiv [Preprint]. 2024 Oct 11:2024.10.10.24315041. doi: 10.1101/2024.10.10.24315041. medRxiv. 2024. PMID: 39417133 Free PMC article. Preprint.
[No title available]
[No authors listed] [No authors listed] PMID: 39750929
Contributions of genetic variation in astrocytes to cell and molecular mechanisms of risk and resilience to late onset Alzheimer's disease.
Lee H, Pearse RV, Lish AM, Pan C, Augur ZM, Terzioglu G, Gaur P, Liao M, Fujita M, Tio ES, Duong DM, Felsky D, Seyfried NT, Menon V, Bennett DA, De Jager PL, Young-Pearse TL. Lee H, et al. Among authors: de jager pl. bioRxiv [Preprint]. 2024 Jul 31:2024.07.31.605928. doi: 10.1101/2024.07.31.605928. bioRxiv. 2024. PMID: 39211227 Free PMC article. Preprint.
Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries.
García-Marín LM, Campos AI, Diaz-Torres S, Rabinowitz JA, Ceja Z, Mitchell BL, Grasby KL, Thorp JG, Agartz I, Alhusaini S, Ames D, Amouyel P, Andreassen OA, Arfanakis K, Vasquez AA, Armstrong NJ, Athanasiu L, Bastin ME, Beiser AS, Bennett DA, Bis JC, Boks MP, Boomsma DI, Brodaty H, Brouwer RM, Buitelaar JK, Burkhardt R, Cahn W, Calhoun VD, Carmichael OT, Chakravarty M, Chen Q, Ching CRK, Cichon S, Crespo-Facorro B, Crivello F, Dale AM, Smith GD, de Geus EJ, De Jager PL, de Zubicaray GI, Debette S, DeCarli C, Depondt C, Desrivières S, Djurovic S, Ehrlich S, Erk S, Espeseth T, Fernández G, Filippi I, Fisher SE, Fleischman DA, Fletcher E, Fornage M, Forstner AJ, Francks C, Franke B, Ge T, Goldman AL, Grabe HJ, Green RC, Grimm O, Groenewold NA, Gruber O, Gudnason V, Håberg AK, Haukvik UK, Heinz A, Hibar DP, Hilal S, Himali JJ, Ho BC, Hoehn DF, Hoekstra PJ, Hofer E, Hoffmann W, Holmes AJ, Homuth G, Hosten N, Ikram MK, Ipser JC, Jack CR Jr, Jahanshad N, Jönsson EG, Kahn RS, Kanai R, Klein M, Knol MJ, Launer LJ, Lawrie SM, Hellard SL, Lee PH, Lemaître H, Li S, Liewald DC, Lin H, Longstreth WT Jr, Lopez OL, Luciano M, Maillard P, Marquand AF, Martin NG, Martinot JL, M… See abstract for full author list ➔ García-Marín LM, et al. Among authors: de jager pl, de geus ej, de zubicaray gi. medRxiv [Preprint]. 2024 Aug 15:2024.08.13.24311922. doi: 10.1101/2024.08.13.24311922. medRxiv. 2024. Update in: Nat Genet. 2024 Nov;56(11):2333-2344. doi: 10.1038/s41588-024-01951-z PMID: 39371125 Free PMC article. Updated. Preprint.
A cross-disease resource of living human microglia identifies disease-enriched subsets and tool compounds recapitulating microglial states.
Tuddenham JF, Taga M, Haage V, Marshe VS, Roostaei T, White C, Lee AJ, Fujita M, Khairallah A, Zhang Y, Green G, Hyman B, Frosch M, Hopp S, Beach TG, Serrano GE, Corboy J, Habib N, Klein HU, Soni RK, Teich AF, Hickman RA, Alcalay RN, Shneider N, Schneider J, Sims PA, Bennett DA, Olah M, Menon V, De Jager PL. Tuddenham JF, et al. Among authors: de jager pl. Nat Neurosci. 2024 Dec;27(12):2521-2537. doi: 10.1038/s41593-024-01764-7. Epub 2024 Oct 15. Nat Neurosci. 2024. PMID: 39406950
Relation of CMV and brain atrophy to trajectories of immunosenescence in diverse populations.
Touil H, Luquez T, Comandante-Lou N, Lee AJ, Fujita M, Habeck C, Kroshilina A, Hegewisch-Solloa E, McInvale J, Zuroff L, Isnard S, Walker E, Zhang L, Routy JP, Zhang Y, Mace EM, Klotz L, Wiendl H, Xia Z, Bar-Or A, Menon V, Stern Y, De Jager PL. Touil H, et al. Among authors: de jager pl. bioRxiv [Preprint]. 2024 Nov 21:2024.10.07.614568. doi: 10.1101/2024.10.07.614568. bioRxiv. 2024. PMID: 39416188 Free PMC article. Preprint.
589 results