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Identification and development of TRPM4 antagonists to counteract neuronal excitotoxicity.
Binkle-Ladisch L, Pironet A, Zaliani A, Alcouffe C, Mensching D, Haferkamp U, Willing A, Woo MS, Erdmann A, Jessen T, Hess SD, Gribbon P, Pless O, Vennekens R, Friese MA. Binkle-Ladisch L, et al. Among authors: vennekens r. iScience. 2024 Nov 19;27(12):111425. doi: 10.1016/j.isci.2024.111425. eCollection 2024 Dec 20. iScience. 2024. PMID: 39687019 Free PMC article.
TRPM4 inhibition by meclofenamate suppresses Ca2+-dependent triggered arrhythmias.
Vandewiele F, Pironet A, Jacobs G, Kecskés M, Wegener J, Kerselaers S, Hendrikx L, Verelst J, Philippaert K, Oosterlinck W, Segal A, Van Den Broeck E, Pinto S, Priori SG, Lehnart SE, Nilius B, Voets T, Vennekens R. Vandewiele F, et al. Among authors: vennekens r. Eur Heart J. 2022 Oct 21;43(40):4195-4207. doi: 10.1093/eurheartj/ehac354. Eur Heart J. 2022. PMID: 35822895
TRPM4.
Mathar I, Jacobs G, Kecskes M, Menigoz A, Philippaert K, Vennekens R. Mathar I, et al. Among authors: vennekens r. Handb Exp Pharmacol. 2014;222:461-87. doi: 10.1007/978-3-642-54215-2_18. Handb Exp Pharmacol. 2014. PMID: 24756717 Review.
Steviol glycosides enhance pancreatic beta-cell function and taste sensation by potentiation of TRPM5 channel activity.
Philippaert K, Pironet A, Mesuere M, Sones W, Vermeiren L, Kerselaers S, Pinto S, Segal A, Antoine N, Gysemans C, Laureys J, Lemaire K, Gilon P, Cuypers E, Tytgat J, Mathieu C, Schuit F, Rorsman P, Talavera K, Voets T, Vennekens R. Philippaert K, et al. Among authors: vennekens r. Nat Commun. 2017 Mar 31;8:14733. doi: 10.1038/ncomms14733. Nat Commun. 2017. PMID: 28361903 Free PMC article.
107 results