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Identification and development of TRPM4 antagonists to counteract neuronal excitotoxicity.
Binkle-Ladisch L, Pironet A, Zaliani A, Alcouffe C, Mensching D, Haferkamp U, Willing A, Woo MS, Erdmann A, Jessen T, Hess SD, Gribbon P, Pless O, Vennekens R, Friese MA. Binkle-Ladisch L, et al. Among authors: woo ms. iScience. 2024 Nov 19;27(12):111425. doi: 10.1016/j.isci.2024.111425. eCollection 2024 Dec 20. iScience. 2024. PMID: 39687019 Free PMC article.
The NR4A2/VGF pathway fuels inflammation-induced neurodegeneration via promoting neuronal glycolysis.
Woo MS, Bal LC, Winschel I, Manca E, Walkenhorst M, Sevgili B, Sonner JK, Di Liberto G, Mayer C, Binkle-Ladisch L, Rothammer N, Unger L, Raich L, Hadjilaou A, Noli B, Manai AL, Vieira V, Meurs N, Wagner I, Pless O, Cocco C, Stephens SB, Glatzel M, Merkler D, Friese MA. Woo MS, et al. J Clin Invest. 2024 Jun 18;134(16):e177692. doi: 10.1172/JCI177692. J Clin Invest. 2024. PMID: 39145444 Free PMC article.
Multi-dimensional and longitudinal systems profiling reveals predictive pattern of severe COVID-19.
Woo MS, Haag F, Nierhaus A, Jarczak D, Roedl K, Mayer C, Brehm TT, van der Meirschen M, Hennigs A, Christopeit M, Fiedler W, Karagiannis P, Burdelski C, Schultze A, Huber S, Addo MM, Schmiedel S, Friese MA, Kluge S, Schulze Zur Wiesch J. Woo MS, et al. iScience. 2021 Jul 23;24(7):102752. doi: 10.1016/j.isci.2021.102752. Epub 2021 Jun 19. iScience. 2021. PMID: 34179733 Free PMC article.
The neuropathobiology of multiple sclerosis.
Woo MS, Engler JB, Friese MA. Woo MS, et al. Nat Rev Neurosci. 2024 Jul;25(7):493-513. doi: 10.1038/s41583-024-00823-z. Epub 2024 May 24. Nat Rev Neurosci. 2024. PMID: 38789516 Review.
STING orchestrates the neuronal inflammatory stress response in multiple sclerosis.
Woo MS, Mayer C, Binkle-Ladisch L, Sonner JK, Rosenkranz SC, Shaposhnykov A, Rothammer N, Tsvilovskyy V, Lorenz SM, Raich L, Bal LC, Vieira V, Wagner I, Bauer S, Glatzel M, Conrad M, Merkler D, Freichel M, Friese MA. Woo MS, et al. Cell. 2024 Jul 25;187(15):4043-4060.e30. doi: 10.1016/j.cell.2024.05.031. Epub 2024 Jun 14. Cell. 2024. PMID: 38878778 Free article.
The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2.
Krasemann S, Haferkamp U, Pfefferle S, Woo MS, Heinrich F, Schweizer M, Appelt-Menzel A, Cubukova A, Barenberg J, Leu J, Hartmann K, Thies E, Littau JL, Sepulveda-Falla D, Zhang L, Ton K, Liang Y, Matschke J, Ricklefs F, Sauvigny T, Sperhake J, Fitzek A, Gerhartl A, Brachner A, Geiger N, König EM, Bodem J, Franzenburg S, Franke A, Moese S, Müller FJ, Geisslinger G, Claussen C, Kannt A, Zaliani A, Gribbon P, Ondruschka B, Neuhaus W, Friese MA, Glatzel M, Pless O. Krasemann S, et al. Among authors: woo ms. Stem Cell Reports. 2022 Feb 8;17(2):307-320. doi: 10.1016/j.stemcr.2021.12.011. Epub 2022 Jan 20. Stem Cell Reports. 2022. PMID: 35063125 Free PMC article.
161 results