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Page 1
CFTR represses a PDX1 axis to govern pancreatic ductal cell fate.
Rotti PG, Yi Y, Gasser G, Yuan F, Sun X, Apak-Evans I, Wu P, Liu G, Choi S, Reeves R, Scioneaux AE, Zhang Y, Winter M, Liang B, Cunicelli N, Uc A, Norris AW, Sussel L, Wells KL, Engelhardt JF. Rotti PG, et al. iScience. 2024 Nov 15;27(12):111393. doi: 10.1016/j.isci.2024.111393. eCollection 2024 Dec 20. iScience. 2024. PMID: 39687022 Free PMC article.
Transgenic ferret models define pulmonary ionocyte diversity and function.
Yuan F, Gasser GN, Lemire E, Montoro DT, Jagadeesh K, Zhang Y, Duan Y, Ievlev V, Wells KL, Rotti PG, Shahin W, Winter M, Rosen BH, Evans I, Cai Q, Yu M, Walsh SA, Acevedo MR, Pandya DN, Akurathi V, Dick DW, Wadas TJ, Joo NS, Wine JJ, Birket S, Fernandez CM, Leung HM, Tearney GJ, Verkman AS, Haggie PM, Scott K, Bartels D, Meyerholz DK, Rowe SM, Liu X, Yan Z, Haber AL, Sun X, Engelhardt JF. Yuan F, et al. Among authors: rotti pg. Nature. 2023 Sep;621(7980):857-867. doi: 10.1038/s41586-023-06549-9. Epub 2023 Sep 20. Nature. 2023. PMID: 37730992 Free PMC article.
In Situ Analysis Reveals That CFTR Is Expressed in Only a Small Minority of β-Cells in Normal Adult Human Pancreas.
White MG, Maheshwari RR, Anderson SJ, Berlinguer-Palmini R, Jones C, Richardson SJ, Rotti PG, Armour SL, Ding Y, Krasnogor N, Engelhardt JF, Gray MA, Morgan NG, Shaw JAM. White MG, et al. Among authors: rotti pg. J Clin Endocrinol Metab. 2020 May 1;105(5):1366-74. doi: 10.1210/clinem/dgz209. J Clin Endocrinol Metab. 2020. PMID: 31748811 Free PMC article.
In utero and postnatal VX-770 administration rescues multiorgan disease in a ferret model of cystic fibrosis.
Sun X, Yi Y, Yan Z, Rosen BH, Liang B, Winter MC, Evans TIA, Rotti PG, Yang Y, Gray JS, Park SY, Zhou W, Zhang Y, Moll SR, Woody L, Tran DM, Jiang L, Vonk AM, Beekman JM, Negulescu P, Van Goor F, Fiorino DF, Gibson-Corley KN, Engelhardt JF. Sun X, et al. Among authors: rotti pg. Sci Transl Med. 2019 Mar 27;11(485):eaau7531. doi: 10.1126/scitranslmed.aau7531. Sci Transl Med. 2019. PMID: 30918114 Free PMC article.
PyMINEr Finds Gene and Autocrine-Paracrine Networks from Human Islet scRNA-Seq.
Tyler SR, Rotti PG, Sun X, Yi Y, Xie W, Winter MC, Flamme-Wiese MJ, Tucker BA, Mullins RF, Norris AW, Engelhardt JF. Tyler SR, et al. Among authors: rotti pg. Cell Rep. 2019 Feb 12;26(7):1951-1964.e8. doi: 10.1016/j.celrep.2019.01.063. Cell Rep. 2019. PMID: 30759402 Free PMC article.
Submucosal Gland Myoepithelial Cells Are Reserve Stem Cells That Can Regenerate Mouse Tracheal Epithelium.
Lynch TJ, Anderson PJ, Rotti PG, Tyler SR, Crooke AK, Choi SH, Montoro DT, Silverman CL, Shahin W, Zhao R, Jensen-Cody CW, Adamcakova-Dodd A, Evans TIA, Xie W, Zhang Y, Mou H, Herring BP, Thorne PS, Rajagopal J, Yeaman C, Parekh KR, Engelhardt JF. Lynch TJ, et al. Among authors: rotti pg. Cell Stem Cell. 2018 May 3;22(5):779. doi: 10.1016/j.stem.2018.04.007. Cell Stem Cell. 2018. PMID: 29727685 Free PMC article. No abstract available.
Submucosal Gland Myoepithelial Cells Are Reserve Stem Cells That Can Regenerate Mouse Tracheal Epithelium.
Lynch TJ, Anderson PJ, Rotti PG, Tyler SR, Crooke AK, Choi SH, Montoro DT, Silverman CL, Shahin W, Zhao R, Jensen-Cody CW, Adamcakova-Dodd A, Evans TIA, Xie W, Zhang Y, Mou H, Herring BP, Thorne PS, Rajagopal J, Yeaman C, Parekh KR, Engelhardt JF. Lynch TJ, et al. Among authors: rotti pg. Cell Stem Cell. 2018 May 3;22(5):653-667.e5. doi: 10.1016/j.stem.2018.03.017. Epub 2018 Apr 12. Cell Stem Cell. 2018. PMID: 29656941 Free PMC article.
14 results