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Lithocholic acid binds TULP3 to activate sirtuins and AMPK to slow down ageing.
Qu Q, Chen Y, Wang Y, Wang W, Long S, Yang HY, Wu J, Li M, Tian X, Wei X, Liu YH, Xu S, Xiong J, Yang C, Wu Z, Huang X, Xie C, Wu Y, Xu Z, Zhang C, Zhang B, Feng JW, Chen J, Feng Y, Fang H, Lin L, Xie ZK, Sun B, Tian H, Yu Y, Piao HL, Xie XS, Deng X, Zhang CS, Lin SC. Qu Q, et al. Among authors: lin sc. Nature. 2024 Dec 18. doi: 10.1038/s41586-024-08348-2. Online ahead of print. Nature. 2024. PMID: 39695235
Lithocholic acid phenocopies anti-ageing effects of calorie restriction.
Qu Q, Chen Y, Wang Y, Long S, Wang W, Yang HY, Li M, Tian X, Wei X, Liu YH, Xu S, Zhang C, Zhu M, Lam SM, Wu J, Yun C, Chen J, Xue S, Zhang B, Zheng ZZ, Piao HL, Jiang C, Guo H, Shui G, Deng X, Zhang CS, Lin SC. Qu Q, et al. Among authors: lin sc. Nature. 2024 Dec 18. doi: 10.1038/s41586-024-08329-5. Online ahead of print. Nature. 2024. PMID: 39695227
Consensus Recommendations for Studies of Outflow Facility and Intraocular Pressure Regulation Using Ex Vivo Perfusion Approaches.
Acott TS, Fautsch MP, Mao W, Ethier CR, Huang AS, Kelley MJ, Aga M, Bhattacharya SK, Borras T, Bovenkamp D, Chowdhury UR, Clark AF, Dibas MI, Du Y, Elliott MH, Faralli JA, Gong H, Herberg S, Johnstone MA, Kaufman PL, Keller KE, Kelly RA, Krizaj D, Kuehn MH, Li HL, Lieberman R, Lin SC, Liu Y, McDonnell FS, McDowell CM, McLellan GJ, Mzyk P, Nair KS, Overby DR, Peters DM, Raghunathan V, Rao PV, Roddy GW, Sharif NA, Shim MS, Sun Y, Thomson BR, Toris CB, Willoughby CE, Zhang HF, Freddo TF, Fuchshofer R, Hill KR, Karimi A, Kizhatil K, Kopcyznski CC, Liton P, Patel G, Peng M, Pattabiraman PP, Prasanna G, Reina-Torres E, Samples EG, Samples JR, Steel CL, Strohmaier CA, Subramanian P, Sugali CK, van Batenburg-Sherwood J, Wong C, Youngblood H, Zode GS, White E, Stamer WD. Acott TS, et al. Among authors: lin sc. Invest Ophthalmol Vis Sci. 2024 Dec 2;65(14):32. doi: 10.1167/iovs.65.14.32. Invest Ophthalmol Vis Sci. 2024. PMID: 39693082 Review.
BHLH Transcription Factor TCF21 Inhibits Myofibroblast Formation and Cardiac Fibrosis.
Johansen AKZ, Kasam RK, Vagnozzi RJ, Lin SJ, Gomez-Arroyo JG, Shittu A, Bowers SLK, Kuwabara Y, Grimes KM, Warrick K, Sargent MA, Baldwin TA, Quaggin SE, Barski A, Molkentin JD. Johansen AKZ, et al. Circ Res. 2024 Dec 4. doi: 10.1161/CIRCRESAHA.124.325527. Online ahead of print. Circ Res. 2024. PMID: 39629593
2,191 results