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Off-Target Inhibition of Human Dihydroorotate Dehydrogenase (hDHODH) Highlights Challenges in the Development of Fat Mass and Obesity-Associated Protein (FTO) Inhibitors.
Tarullo M, Fernandez Rodriguez G, Iaiza A, Venezia S, Macone A, Incocciati A, Masciarelli S, Marchioni M, Giorgis M, Lolli ML, Fornaseri F, Proietti L, Grebien F, Rosignoli S, Paiardini A, Rotili D, Mai A, Bochenkova E, Caflisch A, Fazi F, Fatica A. Tarullo M, et al. Among authors: masciarelli s. ACS Pharmacol Transl Sci. 2024 Nov 26;7(12):4096-4111. doi: 10.1021/acsptsci.4c00533. eCollection 2024 Dec 13. ACS Pharmacol Transl Sci. 2024. PMID: 39698280
Editorial: Protein homeostasis in growth, development and disease.
Masciarelli S, Fazi F, Hendershot LM. Masciarelli S, et al. Front Cell Dev Biol. 2023 Feb 6;11:1150158. doi: 10.3389/fcell.2023.1150158. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 36814602 Free PMC article. No abstract available.
New insight into the catalytic -dependent and -independent roles of METTL3 in sustaining aberrant translation in chronic myeloid leukemia.
Ianniello Z, Sorci M, Ceci Ginistrelli L, Iaiza A, Marchioni M, Tito C, Capuano E, Masciarelli S, Ottone T, Attrotto C, Rizzo M, Franceschini L, de Pretis S, Voso MT, Pelizzola M, Fazi F, Fatica A. Ianniello Z, et al. Among authors: masciarelli s. Cell Death Dis. 2021 Sep 24;12(10):870. doi: 10.1038/s41419-021-04169-7. Cell Death Dis. 2021. PMID: 34561421 Free PMC article.
Enhancing sensitivity of triple-negative breast cancer to DNA-damaging therapy through chemical inhibition of the m6A methyltransferase METTL3.
Cesaro B, Iaiza A, Piscopo F, Tarullo M, Cesari E, Rotili D, Mai A, Diana A, Londero M, Del Giacco L, Masetti R, Di Leone A, Naro C, Masciarelli S, Fontemaggi G, Sette C, Fazi F, Fatica A. Cesaro B, et al. Among authors: masciarelli s. Cancer Commun (Lond). 2024 Feb;44(2):282-286. doi: 10.1002/cac2.12509. Epub 2023 Dec 15. Cancer Commun (Lond). 2024. PMID: 38102821 Free PMC article. No abstract available.
METTL3-dependent MALAT1 delocalization drives c-Myc induction in thymic epithelial tumors.
Iaiza A, Tito C, Ianniello Z, Ganci F, Laquintana V, Gallo E, Sacconi A, Masciarelli S, De Angelis L, Aversa S, Diso D, Anile M, Petrozza V, Facciolo F, Melis E, Pescarmona E, Venuta F, Marino M, Blandino G, Fontemaggi G, Fatica A, Fazi F. Iaiza A, et al. Among authors: masciarelli s. Clin Epigenetics. 2021 Sep 16;13(1):173. doi: 10.1186/s13148-021-01159-6. Clin Epigenetics. 2021. PMID: 34530916 Free PMC article.
WTAP and m6A-modified circRNAs modulation during stress response in acute myeloid leukemia progenitor cells.
Iaiza A, Mazzanti G, Goeman F, Cesaro B, Cortile C, Corleone G, Tito C, Liccardo F, De Angelis L, Petrozza V, Masciarelli S, Blandino G, Fanciulli M, Fatica A, Fontemaggi G, Fazi F. Iaiza A, et al. Among authors: masciarelli s. Cell Mol Life Sci. 2024 Jun 23;81(1):276. doi: 10.1007/s00018-024-05299-9. Cell Mol Life Sci. 2024. PMID: 38909325 Free PMC article.
48 results