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251 results

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Page 1
Multicohort Analysis of Bronchial Epithelial Cell Expression in Healthy Subjects and Patients with Asthma Reveals Four Clinically Distinct Clusters.
Lee I, Ganesan A, Kalesinskas L, Zheng H, Ahn HC, Christenson S, Erzurum SC, Zein J, Bleecker ER, Meyers DA, Castro M, Fahy JV, Israel E, Jarjour NN, Moore W, Wenzel SE, Mauger DT, Levy BD, Woodruff PG, Ortega VE, Khatri P. Lee I, et al. Among authors: jarjour nn. Am J Respir Cell Mol Biol. 2024 Dec 19. doi: 10.1165/rcmb.2024-0125OC. Online ahead of print. Am J Respir Cell Mol Biol. 2024. PMID: 39700523
Type 1 Immune Responses Related to Viral Infection Influence Corticosteroid Response in Asthma.
Fahy JV, Jackson ND, Sajuthi SP, Pruesse E, Moore CM, Everman JL, Rios C, Tang M, Gauthier M, Wenzel SE, Bleecker ER, Castro M, Comhair SA, Erzurum SC, Hastie AT, Moore W, Israel E, Levy BD, Denlinger L, Jarjour NN, Johansson MW, Mauger DT, Phillips BR, Sumino K, Woodruff PG, Peters MC, Seibold MA; National Heart, Lung, and Blood Institute Severe Asthma Research Program-3. Fahy JV, et al. Among authors: jarjour nn. Am J Respir Crit Care Med. 2024 Nov 27. doi: 10.1164/rccm.202402-0403OC. Online ahead of print. Am J Respir Crit Care Med. 2024. PMID: 39601762
Use of exhaled nitric oxide measurement to identify a reactive, at-risk phenotype among patients with asthma.
Dweik RA, Sorkness RL, Wenzel S, Hammel J, Curran-Everett D, Comhair SA, Bleecker E, Busse W, Calhoun WJ, Castro M, Chung KF, Israel E, Jarjour N, Moore W, Peters S, Teague G, Gaston B, Erzurum SC; National Heart, Lung, and Blood Institute Severe Asthma Research Program. Dweik RA, et al. Am J Respir Crit Care Med. 2010 May 15;181(10):1033-41. doi: 10.1164/rccm.200905-0695OC. Epub 2010 Feb 4. Am J Respir Crit Care Med. 2010. PMID: 20133930 Free PMC article.
The Impact of Insulin Resistance on Loss of Lung Function and Response to Treatment in Asthma.
Peters MC, Schiebler ML, Cardet JC, Johansson MW, Sorkness R, DeBoer MD, Bleecker ER, Meyers DA, Castro M, Sumino K, Erzurum SC, Tattersall MC, Zein JG, Hastie AT, Moore W, Levy BD, Israel E, Phillips BR, Mauger DT, Wenzel SE, Fajt ML, Koliwad SK, Denlinger LC, Woodruff PG, Jarjour NN, Fahy JV; National Heart, Lung, and Blood Institute Severe Asthma Research Program-3. Peters MC, et al. Among authors: jarjour nn. Am J Respir Crit Care Med. 2022 Nov 1;206(9):1096-1106. doi: 10.1164/rccm.202112-2745OC. Am J Respir Crit Care Med. 2022. PMID: 35687105 Free PMC article.
Bronchial epithelial cell transcriptional responses to inhaled corticosteroids dictate severe asthmatic outcomes.
Ginebaugh SP, Hagner M, Ray A, Erzurum SC, Comhair SAA, Denlinger LC, Jarjour NN, Castro M, Woodruff PG, Christenson SA, Bleecker ER, Meyers DA, Hastie AT, Moore WC, Mauger DT, Israel E, Levy BD, Wenzel SE, Camiolo MJ. Ginebaugh SP, et al. Among authors: jarjour nn. J Allergy Clin Immunol. 2023 Jun;151(6):1513-1524. doi: 10.1016/j.jaci.2023.01.028. Epub 2023 Feb 14. J Allergy Clin Immunol. 2023. PMID: 36796454 Free PMC article.
CCL5 is a potential bridge between type 1 and type 2 inflammation in asthma.
Gauthier M, Kale SL, Oriss TB, Gorry M, Ramonell RP, Dalton K, Ray P, Fahy JV, Seibold MA, Castro M, Jarjour N, Gaston B, Bleecker ER, Meyers DA, Moore W, Hastie AT, Israel E, Levy BD, Mauger D, Erzurum S, Comhair SA, Wenzel SE, Ray A. Gauthier M, et al. J Allergy Clin Immunol. 2023 Jul;152(1):94-106.e12. doi: 10.1016/j.jaci.2023.02.028. Epub 2023 Mar 8. J Allergy Clin Immunol. 2023. PMID: 36893862 Free PMC article.
Investigations of a combination of atopic status and age of asthma onset identify asthma subphenotypes.
Li H, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Gaston B, Israel E, Jarjour NN, Levy BD, Mauger DT, Moore WC, Wenzel SE, Zein J, Bleecker ER, Meyers DA, Chen Y, Li X; NHLBI Severe Asthma Research Program (SARP). Li H, et al. Among authors: jarjour nn. J Asthma. 2023 Oct;60(10):1843-1852. doi: 10.1080/02770903.2023.2193634. Epub 2023 Apr 21. J Asthma. 2023. PMID: 36940238 Free PMC article.
Genetic analyses of chr11p15.5 region identify MUC5AC-MUC5B associated with asthma-related phenotypes.
Li X, Li H, Christenson SA, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Gaston BM, Israel E, Jarjour NN, Levy BD, Mauger DT, Moore WC, Zein J, Kaminski N, Wenzel SE, Woodruff PG, Bleecker ER, Meyers DA; NHLBI Severe Asthma Research Program (SARP). Li X, et al. Among authors: jarjour nn. J Asthma. 2023 Oct;60(10):1824-1835. doi: 10.1080/02770903.2023.2193631. Epub 2023 Apr 21. J Asthma. 2023. PMID: 36946148 Free PMC article.
Mitochondrial DNA Copy Number Variation in Asthma Risk, Severity, and Exacerbations.
Xu W, Hong YS, Hu B, Comhair SAA, Janocha AJ, Zein JG, Chen R, Meyers DA, Mauger DT, Ortega VE, Bleecker ER, Castro M, Denlinger LC, Fahy JV, Israel E, Levy BD, Jarjour NN, Moore WC, Wenzel SE, Gaston B, Liu C, Arking DE, Erzurum SC; National Heart, Lung, and Blood Institute (NHLBI) Severe Asthma Research Program (SARP) and TOPMed mtDNA Working Group in NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium. Xu W, et al. Among authors: jarjour nn. medRxiv [Preprint]. 2023 Dec 5:2023.12.05.23299392. doi: 10.1101/2023.12.05.23299392. medRxiv. 2023. Update in: J Allergy Clin Immunol. 2024 Sep 3:S0091-6749(24)00906-0. doi: 10.1016/j.jaci.2024.08.022 PMID: 38106101 Free PMC article. Updated. Preprint.
A Novel Air Trapping Segment Score Identifies Opposing Effects of Obesity and Eosinophilia on Air Trapping in Asthma.
Leung C, Tang M, Huang BK, Fain SB, Hoffman EA, Choi J, Dunican EM, Mauger DT, Denlinger LC, Jarjour NN, Israel E, Levy BD, Wenzel SE, Sumino K, Hastie AT, Schirm J, McCulloch CE, Peters MC, Woodruff PG, Sorkness RL, Castro M, Fahy JV. Leung C, et al. Among authors: jarjour nn. Am J Respir Crit Care Med. 2024 May 15;209(10):1196-1207. doi: 10.1164/rccm.202305-0802OC. Am J Respir Crit Care Med. 2024. PMID: 38113166
251 results