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Multicohort Analysis of Bronchial Epithelial Cell Expression in Healthy Subjects and Patients with Asthma Reveals Four Clinically Distinct Clusters.
Lee I, Ganesan A, Kalesinskas L, Zheng H, Ahn HC, Christenson S, Erzurum SC, Zein J, Bleecker ER, Meyers DA, Castro M, Fahy JV, Israel E, Jarjour NN, Moore W, Wenzel SE, Mauger DT, Levy BD, Woodruff PG, Ortega VE, Khatri P. Lee I, et al. Among authors: zheng h. Am J Respir Cell Mol Biol. 2024 Dec 19. doi: 10.1165/rcmb.2024-0125OC. Online ahead of print. Am J Respir Cell Mol Biol. 2024. PMID: 39700523
International multi-cohort analysis identifies novel framework for quantifying immune dysregulation in critical illness: results of the SUBSPACE consortium.
Moore AR, Zheng H, Ganesan A, Hasin-Brumshtein Y, Maddali MV, Levitt JE, van der Poll T, Scicluna BP, Giamarellos-Bourboulis EJ, Kotsaki A, Martin-Loeches I, Garduno A, Rothman RE, Sevransky J, Wright DW, Atreya MR, Moldawer LL, Efron PA, Marcela K, Karvunidis T, Giannini HM, Meyer NJ, Sweeney TE, Rogers AJ, Khatri P. Moore AR, et al. Among authors: zheng h. bioRxiv [Preprint]. 2024 Nov 15:2024.11.12.623298. doi: 10.1101/2024.11.12.623298. bioRxiv. 2024. PMID: 39605502 Free PMC article. Preprint.
Systems immunology of transcriptional responses to viral infection identifies conserved antiviral pathways across macaques and humans.
Ratnasiri K, Zheng H, Toh J, Yao Z, Duran V, Donato M, Roederer M, Kamath M, Todd JM, Gagne M, Foulds KE, Francica JR, Corbett KS, Douek DC, Seder RA, Einav S, Blish CA, Khatri P. Ratnasiri K, et al. Among authors: zheng h. Cell Rep. 2024 Feb 27;43(2):113706. doi: 10.1016/j.celrep.2024.113706. Epub 2024 Jan 30. Cell Rep. 2024. PMID: 38294906 Free PMC article.
Integrative systems biology reveals NKG2A-biased immune responses correlate with protection in infectious disease, autoimmune disease, and cancer.
Chen DG, Xie J, Choi J, Ng RH, Zhang R, Li S, Edmark R, Zheng H, Solomon B, Campbell KM, Medina E, Ribas A, Khatri P, Lanier LL, Mease PJ, Goldman JD, Su Y, Heath JR. Chen DG, et al. Among authors: zheng h. Cell Rep. 2024 Mar 26;43(3):113872. doi: 10.1016/j.celrep.2024.113872. Epub 2024 Feb 29. Cell Rep. 2024. PMID: 38427562 Free PMC article.
Prediction of HLA genotypes from single-cell transcriptome data.
Solomon BD, Zheng H, Dillon LW, Goldman JD, Hourigan CS, Heath JR, Khatri P. Solomon BD, et al. Among authors: zheng h. Front Immunol. 2023 Apr 25;14:1146826. doi: 10.3389/fimmu.2023.1146826. eCollection 2023. Front Immunol. 2023. PMID: 37180102 Free PMC article.
Multi-cohort analysis of host immune response identifies conserved protective and detrimental modules associated with severity across viruses.
Zheng H, Rao AM, Dermadi D, Toh J, Murphy Jones L, Donato M, Liu Y, Su Y, Dai CL, Kornilov SA, Karagiannis M, Marantos T, Hasin-Brumshtein Y, He YD, Giamarellos-Bourboulis EJ, Heath JR, Khatri P. Zheng H, et al. Immunity. 2021 Apr 13;54(4):753-768.e5. doi: 10.1016/j.immuni.2021.03.002. Epub 2021 Mar 24. Immunity. 2021. PMID: 33765435 Free PMC article.
Derivation, validation, and transcriptomic assessment of pediatric septic shock phenotypes identified through latent profile analyses: Results from a prospective multi-center observational cohort.
Atreya MR, Huang M, Moore AR, Zheng H, Hasin-Brumshtein Y, Fitzgerald JC, Weiss SL, Cvijanovich NZ, Bigham MT, Jain PN, Schwarz AJ, Lutfi R, Nowak J, Thomas NJ, Quasney M, Dahmer MK, Baines T, Haileselassie B, Lautz AJ, Stanski NL, Standage SW, Kaplan JM, Zingarelli B, Sweeney TE, Khatri P, Sanchez-Pinto LN, Kamaleswaran R. Atreya MR, et al. Among authors: zheng h. Res Sq [Preprint]. 2023 Dec 6:rs.3.rs-3692289. doi: 10.21203/rs.3.rs-3692289/v1. Res Sq. 2023. PMID: 38105983 Free PMC article. Preprint.
Impaired innate and adaptive immune responses to BNT162b2 SARS-CoV-2 vaccination in systemic lupus erythematosus.
Sarin KY, Zheng H, Chaichian Y, Arunachalam PS, Swaminathan G, Eschholz A, Gao F, Wirz OF, Lam B, Yang E, Lee LW, Feng A, Lewis MA, Lin J, Maecker HT, Boyd SD, Davis MM, Nadeau KC, Pulendran B, Khatri P, Utz PJ, Zaba LC. Sarin KY, et al. Among authors: zheng h. JCI Insight. 2024 Mar 8;9(5):e176556. doi: 10.1172/jci.insight.176556. JCI Insight. 2024. PMID: 38456511 Free PMC article.
Identification of Distinct Inflammatory Programs and Biomarkers in Systemic Juvenile Idiopathic Arthritis and Related Lung Disease by Serum Proteome Analysis.
Chen G, Deutsch GH, Schulert GS, Zheng H, Jang S, Trapnell B, Lee PY, Macaubas C, Ho K, Schneider C, Saper VE, de Jesus AA, Krasnow MA, Grom A, Goldbach-Mansky R, Khatri P, Mellins ED, Canna SW. Chen G, et al. Among authors: zheng h. Arthritis Rheumatol. 2022 Jul;74(7):1271-1283. doi: 10.1002/art.42099. Epub 2022 May 31. Arthritis Rheumatol. 2022. PMID: 35189047 Free PMC article.
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