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Page 1
Longer-term survival, quality of life, and cost-effectiveness of conservative versus liberal oxygenation targets in critically ill children: a pre-specified analysis from Oxy-PICU, a multicentre, open, parallel-group, randomised controlled trial.
Moler-Zapata S, Peters MJ, Gould DW, Giallongo E, Orzol M, Ray S, Thomas K, Chang I, O'Neill L, Agbeko R, Au C, Draper E, Elliot-Major L, Lampro L, Pappachan J, Peters S, Ramnarayan P, Rowan KM, Harrison DA, Mouncey PR, Sadique Z; Oxy-PICU Investigators of the Paediatric Critical Care Society Study Group (PCCS-SG). Moler-Zapata S, et al. Among authors: lampro l. Lancet Child Adolesc Health. 2025 Jan;9(1):16-24. doi: 10.1016/S2352-4642(24)00294-3. Lancet Child Adolesc Health. 2025. PMID: 39701658 Clinical Trial.
Oxidative stress, redox status and surfactant metabolism in mechanically ventilated patients receiving different approaches to oxygen therapy (MecROX): An observational study protocol for mechanistic evaluation.
Dushianthan A, Martin D, Mouncey P, Shahid T, Lampro L, Johnson AF, Goss V, Cazley A, Herbert W, Jones W, Lamond M, Neyroud F, Salmon K, Lentaigne J, Minnion M, Panchal M, Koster G, Moyses H, Postle AD, Feelisch M, Grocott MPW. Dushianthan A, et al. Among authors: lampro l. NIHR Open Res. 2024 Jul 8;4:23. doi: 10.3310/nihropenres.13567.2. eCollection 2024. NIHR Open Res. 2024. PMID: 39145107 Free PMC article.
Ethnicity and Observed Oxygen Saturations, Fraction of Inspired Oxygen, and Clinical Outcomes: A Post-Hoc Analysis of the Oxy-PICU Trial of Conservative Oxygenation.
Jones GAL, Wiegand M, Ray S, Gould DW, Agbeko R, Giallongo E, Charles WN, Orzol M, O'Neill L, Lampro L, Lillie J, Pappachan J, Ramnarayan P, Harrison DA, Mouncey PR, Peters MJ; Oxy-PICU Investigators of the Pediatric Critical Care Society Study Group. Jones GAL, et al. Among authors: lampro l. Pediatr Crit Care Med. 2024 Oct 1;25(10):912-917. doi: 10.1097/PCC.0000000000003583. Epub 2024 Jul 19. Pediatr Crit Care Med. 2024. PMID: 39028216 Clinical Trial.
Evaluating the clinical and cost-effectiveness of a conservative approach to oxygen therapy for invasively ventilated adults in intensive care: Protocol for the UK-ROX trial.
Martin DS, Shahid T, Gould DW, Richards-Belle A, Doidge JC, Camsooksai J, Charles WN, Davey M, Francis Johnson A, Garrett RM, Grocott MP, Jones J, Lampro L, Miller L, O'Driscoll BR, Rostron AJ, Sadique Z, Szakmany T, Young PJ, Rowan KM, Harrison DA, Mouncey PR. Martin DS, et al. Among authors: lampro l. J Intensive Care Soc. 2024 Apr 11;25(2):223-230. doi: 10.1177/17511437241239880. eCollection 2024 May. J Intensive Care Soc. 2024. PMID: 38737312 Free PMC article.
Protocol for a Randomized Controlled Trial to Evaluate a Permissive Blood Pressure Target Versus Usual Care in Critically Ill Children with Hypotension (PRESSURE).
Darnell R, Brown A, Laing E, Edwards J, Harrison DA, Manning JC, Peters MJ, Ramnarayan P, Ray S, Sadique Z, Scholefield BR, Shortt D, Lampro L, Au C, Rowan KM, Mouncey P, Inwald DP; Protocolised Evaluation of Permissive Blood Pressure Targets Versus Usual Care (PRESSURE) Trial Investigators on behalf of the U.K. Paediatric Critical Care Society Study Group (PCCS-SG). Darnell R, et al. Among authors: lampro l. Pediatr Crit Care Med. 2024 Jul 1;25(7):629-637. doi: 10.1097/PCC.0000000000003516. Epub 2024 Apr 17. Pediatr Crit Care Med. 2024. PMID: 38629915 Free PMC article.
Conservative versus liberal oxygenation targets in critically ill children (Oxy-PICU): a UK multicentre, open, parallel-group, randomised clinical trial.
Peters MJ, Gould DW, Ray S, Thomas K, Chang I, Orzol M, O'Neill L, Agbeko R, Au C, Draper E, Elliot-Major L, Giallongo E, Jones GAL, Lampro L, Lillie J, Pappachan J, Peters S, Ramnarayan P, Sadique Z, Rowan KM, Harrison DA, Mouncey PR; Oxy-PICU Investigators of the Paediatric Critical Care Society Study Group (PCCS-SG). Peters MJ, et al. Among authors: lampro l. Lancet. 2024 Jan 27;403(10424):355-364. doi: 10.1016/S0140-6736(23)01968-2. Epub 2023 Dec 1. Lancet. 2024. PMID: 38048787 Free article. Clinical Trial.
Simvastatin in Critically Ill Patients with Covid-19.
REMAP-CAP Investigators; Hills TE, Lorenzi E, Berry LR, Shyamsundar M, Al-Beidh F, Annane D, Arabi Y, Aryal D, Au C, Beane A, Bhimani Z, Bonten M, Bradbury CA, Brunkhorst FM, Burrell A, Buxton M, Calfee CS, Cecconi M, Cheng AC, Cove ME, Detry MA, Estcourt LJ, Fitzgerald M, Goligher EC, Goossens H, Green C, Haniffa R, Harrison DA, Hashmi M, Higgins AM, Horvat C, Huang DT, Ichihara N, Jayakumar D, Kruger PS, Lamontagne F, Lampro L, Lawler PR, Marshall JC, Mason AJ, McGlothlin A, McGuinness S, McQuilten ZK, McVerry BJ, Mouncey PR, Murthy S, Neal MD, Nichol AD, O'Kane CM, Parke RL, Parker JC, Rabindrarajan E, Reyes LF, Rowan KM, Saito H, Santos M, Saunders CT, Seymour CW, Shankar-Hari M, Sinha P, Thompson BT, Turgeon AF, Turner AM, van de Veerdonk F, Weis S, Young IS, Zarychanski R, Lewis RJ, McArthur CJ, Angus DC, Berry SM, Derde LPG, Webb SA, Gordon AC, McAuley DF. REMAP-CAP Investigators, et al. Among authors: lampro l. N Engl J Med. 2023 Dec 21;389(25):2341-2354. doi: 10.1056/NEJMoa2309995. Epub 2023 Oct 25. N Engl J Med. 2023. PMID: 37888913 Free PMC article. Clinical Trial.
Intravenous Vitamin C for Patients Hospitalized With COVID-19: Two Harmonized Randomized Clinical Trials.
LOVIT-COVID Investigators, on behalf of the Canadian Critical Care Trials Group, and the REMAP-CAP Investigators; Adhikari NKJ, Hashmi M, Tirupakuzhi Vijayaraghavan BK, Haniffa R, Beane A, Webb SA, Angus DC, Gordon AC, Cook DJ, Guyatt GH, Berry LR, Lorenzi E, Mouncey PR, Au C, Pinto R, Ménard J, Sprague S, Masse MH, Huang DT, Heyland DK, Nichol AD, McArthur CJ, de Man A, Al-Beidh F, Annane D, Anstey M, Arabi YM, Battista MC, Berry S, Bhimani Z, Bonten MJM, Bradbury CA, Brant EB, Brunkhorst FM, Burrell A, Buxton M, Cecconi M, Cheng AC, Cohen D, Cove ME, Day AG, Derde LPG, Detry MA, Estcourt LJ, Fagbodun EO, Fitzgerald M, Goossens H, Green C, Higgins AM, Hills TE, Horvat C, Ichihara N, Jayakumar D, Kanji S, Khoso MN, Lawler PR, Lewis RJ, Litton E, Marshall JC, McAuley DF, McGlothlin A, McGuinness SP, McQuilten ZK, McVerry BJ, Murthy S, Parke RL, Parker JC, Reyes LF, Rowan KM, Saito H, Salahuddin N, Santos MS, Saunders CT, Seymour CW, Shankar-Hari M, Tolppa T, Trapani T, Turgeon AF, Turner AM, Udy AA, van de Veerdonk FL, Zarychanski R, Lamontagne F. LOVIT-COVID Investigators, on behalf of the Canadian Critical Care Trials Group, and the REMAP-CAP Investigators, et al. JAMA. 2023 Nov 14;330(18):1745-1759. doi: 10.1001/jama.2023.21407. JAMA. 2023. PMID: 37877585 Free PMC article.
Effect of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Initiation on Organ Support-Free Days in Patients Hospitalized With COVID-19: A Randomized Clinical Trial.
Writing Committee for the REMAP-CAP Investigators; Lawler PR, Derde LPG, van de Veerdonk FL, McVerry BJ, Huang DT, Berry LR, Lorenzi E, van Kimmenade R, Gommans F, Vaduganathan M, Leaf DE, Baron RM, Kim EY, Frankfurter C, Epelman S, Kwan Y, Grieve R, O'Neill S, Sadique Z, Puskarich M, Marshall JC, Higgins AM, Mouncey PR, Rowan KM, Al-Beidh F, Annane D, Arabi YM, Au C, Beane A, van Bentum-Puijk W, Bonten MJM, Bradbury CA, Brunkhorst FM, Burrell A, Buzgau A, Buxton M, Cecconi M, Cheng AC, Cove M, Detry MA, Estcourt LJ, Ezekowitz J, Fitzgerald M, Gattas D, Godoy LC, Goossens H, Haniffa R, Harrison DA, Hills T, Horvat CM, Ichihara N, Lamontagne F, Linstrum KM, McAuley DF, McGlothlin A, McGuinness SP, McQuilten Z, Murthy S, Nichol AD, Owen DRJ, Parke RL, Parker JC, Pollock KM, Reyes LF, Saito H, Santos MS, Saunders CT, Seymour CW, Shankar-Hari M, Singh V, Turgeon AF, Turner AM, Zarychanski R, Green C, Lewis RJ, Angus DC, Berry S, Gordon AC, McArthur CJ, Webb SA. Writing Committee for the REMAP-CAP Investigators, et al. JAMA. 2023 Apr 11;329(14):1183-1196. doi: 10.1001/jama.2023.4480. JAMA. 2023. PMID: 37039790 Free PMC article. Clinical Trial.