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Longer-term survival, quality of life, and cost-effectiveness of conservative versus liberal oxygenation targets in critically ill children: a pre-specified analysis from Oxy-PICU, a multicentre, open, parallel-group, randomised controlled trial.
Moler-Zapata S, Peters MJ, Gould DW, Giallongo E, Orzol M, Ray S, Thomas K, Chang I, O'Neill L, Agbeko R, Au C, Draper E, Elliot-Major L, Lampro L, Pappachan J, Peters S, Ramnarayan P, Rowan KM, Harrison DA, Mouncey PR, Sadique Z; Oxy-PICU Investigators of the Paediatric Critical Care Society Study Group (PCCS-SG). Moler-Zapata S, et al. Among authors: orzol m. Lancet Child Adolesc Health. 2025 Jan;9(1):16-24. doi: 10.1016/S2352-4642(24)00294-3. Lancet Child Adolesc Health. 2025. PMID: 39701658 Clinical Trial.
Ethnicity and Observed Oxygen Saturations, Fraction of Inspired Oxygen, and Clinical Outcomes: A Post-Hoc Analysis of the Oxy-PICU Trial of Conservative Oxygenation.
Jones GAL, Wiegand M, Ray S, Gould DW, Agbeko R, Giallongo E, Charles WN, Orzol M, O'Neill L, Lampro L, Lillie J, Pappachan J, Ramnarayan P, Harrison DA, Mouncey PR, Peters MJ; Oxy-PICU Investigators of the Pediatric Critical Care Society Study Group. Jones GAL, et al. Among authors: orzol m. Pediatr Crit Care Med. 2024 Oct 1;25(10):912-917. doi: 10.1097/PCC.0000000000003583. Epub 2024 Jul 19. Pediatr Crit Care Med. 2024. PMID: 39028216 Clinical Trial.
Conservative versus liberal oxygenation targets in critically ill children (Oxy-PICU): a UK multicentre, open, parallel-group, randomised clinical trial.
Peters MJ, Gould DW, Ray S, Thomas K, Chang I, Orzol M, O'Neill L, Agbeko R, Au C, Draper E, Elliot-Major L, Giallongo E, Jones GAL, Lampro L, Lillie J, Pappachan J, Peters S, Ramnarayan P, Sadique Z, Rowan KM, Harrison DA, Mouncey PR; Oxy-PICU Investigators of the Paediatric Critical Care Society Study Group (PCCS-SG). Peters MJ, et al. Among authors: orzol m. Lancet. 2024 Jan 27;403(10424):355-364. doi: 10.1016/S0140-6736(23)01968-2. Epub 2023 Dec 1. Lancet. 2024. PMID: 38048787 Free article. Clinical Trial.
Protocol for a Randomized Multiple Center Trial of Conservative Versus Liberal Oxygenation Targets in Critically Ill Children (Oxy-PICU): Oxygen in Pediatric Intensive Care.
Chang I, Thomas K, O'Neill Gutierrez L, Peters S, Agbeko R, Au C, Draper E, Jones GAL, Major LE, Orzol M, Pappachan J, Ramnarayan P, Ray S, Sadique Z, Gould DW, Harrison DA, Rowan KM, Mouncey PR, Peters MJ. Chang I, et al. Among authors: orzol m. Pediatr Crit Care Med. 2022 Sep 1;23(9):736-744. doi: 10.1097/PCC.0000000000003008. Epub 2022 Jun 14. Pediatr Crit Care Med. 2022. PMID: 35699737 Free PMC article.