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Multimodal neuroimaging biomarkers and subtle cognitive decline in a population-based cohort without dementia.
Weinstein AM, Fang F, Chang CH, Cohen A, Lopresti BJ, Laymon CM, Nadkarni NK, Aizenstein HJ, Villemagne VL, Ilyas Kamboh M, Elizabeth Shaaban C, Gogniat MA, Wu M, Karikari TK, Ganguli M, Snitz BE. Weinstein AM, et al. Among authors: laymon cm. J Alzheimers Dis. 2024 Dec 19:13872877241303926. doi: 10.1177/13872877241303926. Online ahead of print. J Alzheimers Dis. 2024. PMID: 39702989
Timeline to symptomatic Alzheimer's disease in people with Down syndrome as assessed by amyloid-PET and tau-PET: a longitudinal cohort study.
Schworer EK, Zammit MD, Wang J, Handen BL, Betthauser T, Laymon CM, Tudorascu DL, Cohen AD, Zaman SH, Ances BM, Mapstone M, Head E, Christian BT, Hartley SL; Alzheimer's Biomarker Consortium–Down Syndrome (ABC–DS). Schworer EK, et al. Among authors: laymon cm. Lancet Neurol. 2024 Dec;23(12):1214-1224. doi: 10.1016/S1474-4422(24)00426-5. Lancet Neurol. 2024. PMID: 39577922
Amyloid age and tau PET timeline to symptomatic Alzheimer's disease in Down syndrome.
Schworer EK, Zammit MD, Wang J, Handen BL, Betthauser T, Laymon CM, Tudorascu DL, Cohen AD, Zaman SH, Ances BM, Mapstone M, Head E, Klunk WE, Christian BT, Hartley SL; Alzheimer Biomarker Consortium – Down Syndrome (ABC-DS). Schworer EK, et al. Among authors: laymon cm. medRxiv [Preprint]. 2024 Aug 9:2024.08.08.24311702. doi: 10.1101/2024.08.08.24311702. medRxiv. 2024. PMID: 39211859 Free PMC article. Preprint.
Kinetic modeling of the monoamine oxidase-B radioligand [18F]SMBT-1 in human brain with positron emission tomography.
Lopresti BJ, Stehouwer J, Reese AC, Mason NS, Royse SK, Narendran R, Laymon CM, Lopez OL, Cohen AD, Mathis CA, Villemagne VL. Lopresti BJ, et al. Among authors: laymon cm. J Cereb Blood Flow Metab. 2024 Nov;44(11):1262-1276. doi: 10.1177/0271678X241254679. Epub 2024 May 12. J Cereb Blood Flow Metab. 2024. PMID: 38735059 Free PMC article.
Comparison of tau spread in people with Down syndrome versus autosomal-dominant Alzheimer's disease: a cross-sectional study.
Wisch JK, McKay NS, Boerwinkle AH, Kennedy J, Flores S, Handen BL, Christian BT, Head E, Mapstone M, Rafii MS, O'Bryant SE, Price JC, Laymon CM, Krinsky-McHale SJ, Lai F, Rosas HD, Hartley SL, Zaman S, Lott IT, Tudorascu D, Zammit M, Brickman AM, Lee JH, Bird TD, Cohen A, Chrem P, Daniels A, Chhatwal JP, Cruchaga C, Ibanez L, Jucker M, Karch CM, Day GS, Lee JH, Levin J, Llibre-Guerra J, Li Y, Lopera F, Roh JH, Ringman JM, Supnet-Bell C, van Dyck CH, Xiong C, Wang G, Morris JC, McDade E, Bateman RJ, Benzinger TLS, Gordon BA, Ances BM; Alzheimer's Biomarker Consortium-Down syndrome; Dominantly Inherited Alzheimer Network. Wisch JK, et al. Among authors: laymon cm. Lancet Neurol. 2024 May;23(5):500-510. doi: 10.1016/S1474-4422(24)00084-X. Lancet Neurol. 2024. PMID: 38631766
Characterizing the emergence of amyloid and tau burden in Down syndrome.
Zammit MD, Betthauser TJ, McVea AK, Laymon CM, Tudorascu DL, Johnson SC, Hartley SL, Converse AK, Minhas DS, Zaman SH, Ances BM, Stone CK, Mathis CA, Cohen AD, Klunk WE, Handen BL, Christian BT; Alzheimer's Biomarker Consortium - Down Syndrome. Zammit MD, et al. Among authors: laymon cm. Alzheimers Dement. 2024 Jan;20(1):388-398. doi: 10.1002/alz.13444. Epub 2023 Aug 29. Alzheimers Dement. 2024. PMID: 37641577 Free PMC article.
Amyloid- β and tau deposition influences cognitive and functional decline in Down syndrome.
Grigorova M, Mak E, Brown SSG, Beresford-Webb J, Hong YT, Fryer TD, Coles JP, Aigbirhio FI, Tudorascu D, Cohen A, Christian BT, Ances B, Handen BL, Laymon CM, Klunk WE, Clare ICH, Holland AJ, Zaman SH. Grigorova M, et al. Among authors: laymon cm. Neurobiol Aging. 2022 Nov;119:36-45. doi: 10.1016/j.neurobiolaging.2022.07.003. Epub 2022 Jul 21. Neurobiol Aging. 2022. PMID: 35964542 Free PMC article.
80 results