Hackel BJ - Search Results

1

Expression-Dependent Tumor Pretargeting via Engineered Avidity.

Harthorn A, Kuo TH, Torres SW, Lobb RR, Hackel BJ. Harthorn A, et al. Among authors: hackel bj. Mol Pharm. 2024 Dec 20. doi: 10.1021/acs.molpharmaceut.4c01177. Online ahead of print. Mol Pharm. 2024. PMID: 39704255

2

Retargeting CD19 Chimeric Antigen Receptor T Cells via Engineered CD19-Fusion Proteins.

Klesmith JR, Su L, Wu L, Schrack IA, Dufort FJ, Birt A, Ambrose C, Hackel BJ, Lobb RR, Rennert PD. Klesmith JR, et al. Among authors: hackel bj. Mol Pharm. 2019 Aug 5;16(8):3544-3558. doi: 10.1021/acs.molpharmaceut.9b00418. Epub 2019 Jul 15. Mol Pharm. 2019. PMID: 31242389

3

Engineered protein-small molecule conjugates empower selective enzyme inhibition.

Lewis AK, Harthorn A, Johnson SM, Lobb RR, Hackel BJ. Lewis AK, et al. Among authors: hackel bj. Cell Chem Biol. 2022 Feb 17;29(2):328-338.e4. doi: 10.1016/j.chembiol.2021.07.013. Epub 2021 Aug 6. Cell Chem Biol. 2022. PMID: 34363759 Free PMC article.

4

Systematic Evaluation of Protein-Small Molecule Hybrids on the Yeast Surface.

Huang M, Rueda-Garcia M, Harthorn A, Hackel BJ, Van Deventer JA. Huang M, et al. Among authors: hackel bj. ACS Chem Biol. 2024 Feb 16;19(2):325-335. doi: 10.1021/acschembio.3c00524. Epub 2024 Jan 17. ACS Chem Biol. 2024. PMID: 38230650

5

Fine Epitope Mapping of the CD19 Extracellular Domain Promotes Design.

Klesmith JR, Wu L, Lobb RR, Rennert PD, Hackel BJ. Klesmith JR, et al. Among authors: hackel bj. Biochemistry. 2019 Dec 3;58(48):4869-4881. doi: 10.1021/acs.biochem.9b00808. Epub 2019 Nov 21. Biochemistry. 2019. PMID: 31702909

6

Anti-CD19 CAR T cells potently redirected to kill solid tumor cells.

Ambrose C, Su L, Wu L, Dufort FJ, Sanford T, Birt A, Hackel BJ, Hombach A, Abken H, Lobb RR, Rennert PD. Ambrose C, et al. Among authors: hackel bj. PLoS One. 2021 Mar 18;16(3):e0247701. doi: 10.1371/journal.pone.0247701. eCollection 2021. PLoS One. 2021. PMID: 33735268 Free PMC article.

7

Discovery of a Non-competitive TNFR1 Antagonist Affibody with Picomolar Monovalent Potency That Does Not Affect TNFR2 Function.

Vunnam N, Been M, Huber E, Paulson C, Szymonski S, Hackel BJ, Sachs JN. Vunnam N, et al. Among authors: hackel bj. Mol Pharm. 2023 Apr 3;20(4):1884-1897. doi: 10.1021/acs.molpharmaceut.2c00385. Epub 2023 Mar 10. Mol Pharm. 2023. PMID: 36897792 Free PMC article.

8

⁶⁴Cu-Labeled Gp2 Domain for PET Imaging of Epidermal Growth Factor Receptor.

Kruziki MA, Case BA, Chan JY, Zudock EJ, Woldring DR, Yee D, Hackel BJ. Kruziki MA, et al. Among authors: hackel bj. Mol Pharm. 2016 Nov 7;13(11):3747-3755. doi: 10.1021/acs.molpharmaceut.6b00538. Epub 2016 Oct 10. Mol Pharm. 2016. PMID: 27696863 Free PMC article.

9

Chemical End Group Modified Diblock Copolymers Elucidate Anchor and Chain Mechanism of Membrane Stabilization.

Houang EM, Haman KJ, Kim M, Zhang W, Lowe DA, Sham YY, Lodge TP, Hackel BJ, Bates FS, Metzger JM. Houang EM, et al. Among authors: hackel bj. Mol Pharm. 2017 Jul 3;14(7):2333-2339. doi: 10.1021/acs.molpharmaceut.7b00197. Epub 2017 Jun 12. Mol Pharm. 2017. PMID: 28538101 Free PMC article.

10

Targeting Insulin Receptor in Breast Cancer Using Small Engineered Protein Scaffolds.

Chan JY, Hackel BJ, Yee D. Chan JY, et al. Among authors: hackel bj. Mol Cancer Ther. 2017 Jul;16(7):1324-1334. doi: 10.1158/1535-7163.MCT-16-0685. Epub 2017 May 3. Mol Cancer Ther. 2017. PMID: 28468775 Free PMC article.

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