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Page 1
De-escalating and discontinuing disease-modifying therapies in multiple sclerosis.
Androdias G, Lünemann JD, Maillart E, Amato MP, Audoin B, Bruijstens AL, Bsteh G, Butzkueven H, Ciccarelli O, Cobo-Calvo A, Derfuss T, Di Pauli F, Edan G, Enzinger C, Geraldes R, Granziera C, Hacohen Y, Hartung HP, Hynes S, Inglese M, Kappos L, Kuusisto H, Langer-Gould A, Magyari M, Marignier R, Montalban X, Mycko MP, Nourbakhsh B, Oh J, Oreja-Guevara C, Piehl F, Prosperini L, Sastre-Garriga J, Sellebjerg F, Selmaj K, Siva A, Tallantyre E, van Pesch V, Vukusic S, Weinstock-Guttman B, Zipp F, Tintoré M, Iacobaeus E, Stankoff B. Androdias G, et al. Among authors: derfuss t. Brain. 2024 Dec 21:awae409. doi: 10.1093/brain/awae409. Online ahead of print. Brain. 2024. PMID: 39707906
Neurofilament Light Chain as a Discriminator of Disease Activity Status in MOG Antibody-Associated Disease.
Gomes ABAGR, Kim SH, Pretzsch R, Kulsvehagen L, Schaedelin S, Lerner J, Wetzel NS, Benkert P, Maleska Maceski A, Hyun JW, Lecourt AC, Lipps P, Schoeps VA, Matos AMB, Mendes NT, Apóstolos-Pereira SL, Mehling M, Derfuss T, Kappos L, Callegaro D, Kuhle J, Kim HJ, Pröbstel AK. Gomes ABAGR, et al. Among authors: derfuss t. Neurol Neuroimmunol Neuroinflamm. 2025 Jan;12(1):e200347. doi: 10.1212/NXI.0000000000200347. Epub 2024 Dec 20. Neurol Neuroimmunol Neuroinflamm. 2025. PMID: 39705633 Free article.
Serum Glial Fibrillary Acidic Protein and Neurofilament Light Chain Levels Reflect Different Mechanisms of Disease Progression under B-Cell Depleting Treatment in Multiple Sclerosis.
Benkert P, Maleska Maceski A, Schaedelin S, Oechtering J, Zadic A, Vilchez Gomez JF, Melie-Garcia L, Cagol A, Galbusera R, Subramaniam S, Lorscheider J, Galli E, Mueller J, Fischer-Barnicol B, Achtnichts L, Findling O, Lalive PH, Bridel C, Uginet M, Müller S, Pot C, Mathias A, Du Pasquier R, Salmen A, Hoepner R, Chan A, Disanto G, Zecca C, D'Souza M, Hemkens LG, Yaldizli Ö, Derfuss T, Roth P, Gobbi C, Brassat D, Tackenberg B, Pedotti R, Raposo C, Oksenberg J, Wiendl H, Berger K, Hermesdorf M, Piehl F, Conen D, Buser A, Kappos L, Khalil M, Granziera C, Abdelhak A, Leppert D, Willemse EAJ, Kuhle J; Swiss MS Cohort study (SMSC). Benkert P, et al. Among authors: derfuss t. Ann Neurol. 2024 Oct 16. doi: 10.1002/ana.27096. Online ahead of print. Ann Neurol. 2024. PMID: 39411917
Long-term analysis of infections and associated risk factors in patients with multiple sclerosis treated with ocrelizumab: pooled analysis of 13 interventional clinical trials.
Derfuss T, Bermel R, Lin CJ, Hauser SL, Kappos L, Vollmer T, Comi G, Giovannoni G, Hartung HP, Weber MS, Wang J, Jessop N, Chognot C, Craveiro L, Bar-Or A. Derfuss T, et al. Ther Adv Neurol Disord. 2024 Oct 8;17:17562864241277736. doi: 10.1177/17562864241277736. eCollection 2024. Ther Adv Neurol Disord. 2024. PMID: 39399100 Free PMC article.
Case report: Concurrent MOG antibody-associated disease and latent infections in two patients.
Kulsvehagen L, Woelfle T, Ayroza Galvão Ribeiro Gomes AB, Lipps P, Neziraj T, Flammer J, Leuzinger K, Derfuss T, Kuhle J, Papadopoulou A, Pröbstel AK. Kulsvehagen L, et al. Among authors: derfuss t. Front Immunol. 2024 Sep 4;15:1455355. doi: 10.3389/fimmu.2024.1455355. eCollection 2024. Front Immunol. 2024. PMID: 39295869 Free PMC article.
MultiSCRIPT-Cycle 1-a pragmatic trial embedded within the Swiss Multiple Sclerosis Cohort (SMSC) on neurofilament light chain monitoring to inform personalized treatment decisions in multiple sclerosis: a study protocol for a randomized clinical trial.
Janiaud P, Zecca C, Salmen A, Benkert P, Schädelin S, Orleth A, Demuth L, Maceski AM, Granziera C, Oechtering J, Leppert D, Derfuss T, Achtnichts L, Findling O, Roth P, Lalive P, Uginet M, Müller S, Pot C, Hoepner R, Disanto G, Gobbi C, Rooshenas L, Schwenkglenks M, Lambiris MJ, Kappos L, Kuhle J, Yaldizli Ö, Hemkens LG. Janiaud P, et al. Among authors: derfuss t. Trials. 2024 Sep 11;25(1):607. doi: 10.1186/s13063-024-08454-6. Trials. 2024. PMID: 39261900 Free PMC article.
Targeting cytokine networks in neuroinflammatory diseases.
Becher B, Derfuss T, Liblau R. Becher B, et al. Among authors: derfuss t. Nat Rev Drug Discov. 2024 Nov;23(11):862-879. doi: 10.1038/s41573-024-01026-y. Epub 2024 Sep 11. Nat Rev Drug Discov. 2024. PMID: 39261632 Review.
Contrast-Enhancing Lesion Segmentation in Multiple Sclerosis: A Deep Learning Approach Validated in a Multicentric Cohort.
Greselin M, Lu PJ, Melie-Garcia L, Ocampo-Pineda M, Galbusera R, Cagol A, Weigel M, de Oliveira Siebenborn N, Ruberte E, Benkert P, Müller S, Finkener S, Vehoff J, Disanto G, Findling O, Chan A, Salmen A, Pot C, Bridel C, Zecca C, Derfuss T, Lieb JM, Diepers M, Wagner F, Vargas MI, Pasquier RD, Lalive PH, Pravatà E, Weber J, Gobbi C, Leppert D, Kim OC, Cattin PC, Hoepner R, Roth P, Kappos L, Kuhle J, Granziera C. Greselin M, et al. Among authors: derfuss t. Bioengineering (Basel). 2024 Aug 22;11(8):858. doi: 10.3390/bioengineering11080858. Bioengineering (Basel). 2024. PMID: 39199815 Free PMC article.
Presentation and Outcome in S1P-RM and Natalizumab-Associated Progressive Multifocal Leukoencephalopathy: A Multicenter Cohort Study.
Blant JC, De Rossi NN, Gold R, Maurousset A, Kraemer M, Romero-Pinel L, Misu T, Ouallet JC, Pallix Guyot M, Gerevini S, Bakirtzis C, Piñar Morales R, Vlad B, Karypidis P, Moisset X, Derfuss TJ, Jelcic I, Martin-Blondel G, Ayzenberg I, McGraw C, Laplaud DA, Du Pasquier RA, Bernard-Valnet R; for CORPUS and Italian study groups. Blant JC, et al. Among authors: derfuss tj. Neurol Neuroimmunol Neuroinflamm. 2024 Sep;11(5):e200281. doi: 10.1212/NXI.0000000000200281. Epub 2024 Jul 11. Neurol Neuroimmunol Neuroinflamm. 2024. PMID: 38991170 Free PMC article.
Escalating to medium- versus high-efficacy disease modifying therapy after low-efficacy treatment in relapsing remitting multiple sclerosis.
Müller J, Roos I, Kalincik T, Lorscheider J, Galli E, Benkert P, Schädelin S, Sharmin S, Einsiedler M, Hänni P, Schmid J, Kuhle J, Derfuss T, Granziera C, Ziemssen T, Siepmann T, Yaldizli Ö. Müller J, et al. Among authors: derfuss t. Brain Behav. 2024 May;14(5):e3498. doi: 10.1002/brb3.3498. Brain Behav. 2024. PMID: 38688877 Free PMC article.
197 results