Li W - Search Results

1

Chemical dissection of selective myeloid leukemia-1 inhibitors: How they were found and evolved.

Wang L, Chen Y, Zhang M, Liu J, Li H, Liu M, Wu S, Zhang Y, Li W, Wang B. Wang L, et al. Among authors: li w, li h. Eur J Med Chem. 2025 Feb 5;283:117168. doi: 10.1016/j.ejmech.2024.117168. Epub 2024 Dec 15. Eur J Med Chem. 2025. PMID: 39708769 Review.

2

Drug discovery of N-methyl-pyrazole derivatives as potent selective estrogen receptor degrader (SERD) for the treatment of breast cancer.

Dai R, Bao X, Liu C, Yin X, Zhu Z, Zheng Z, Wang B, Yang K, Wen H, Li W, Zhu H, Du Q, Liu J. Dai R, et al. Among authors: li w. Eur J Med Chem. 2024 Dec 5;279:116894. doi: 10.1016/j.ejmech.2024.116894. Epub 2024 Sep 23. Eur J Med Chem. 2024. PMID: 39357315

3

Reversal of subtype-selectivity and function by the introduction of a para-benzamidyl substituent to N-cyclopropylmethyl nornepenthone.

Kong L, Ning K, Liu X, Lu J, Chen B, Ye R, Li Z, Jiang S, Tang S, Chai JR, Fang Y, Lan Y, Mai X, Xie Q, Liu J, Shao L, Fu W, Wang Y, Li W. Kong L, et al. Among authors: li z, li w. Eur J Med Chem. 2023 Oct 5;258:115589. doi: 10.1016/j.ejmech.2023.115589. Epub 2023 Jun 28. Eur J Med Chem. 2023. PMID: 37413884

4

Novel aminothiazoximone-corbelled ethoxycarbonylpyrimidones with antibiofilm activity to conquer Gram-negative bacteria through potential multitargeting effects.

Li W, Yang X, Ahmad N, Zhang SL, Zhou CH. Li W, et al. Eur J Med Chem. 2024 Mar 15;268:116219. doi: 10.1016/j.ejmech.2024.116219. Epub 2024 Feb 13. Eur J Med Chem. 2024. PMID: 38368710

5

Design, synthesis and activity evaluation of quinolinone derivatives as EZH2 inhibitors.

Cai J, You H, Qin X, Wang Y, Li W. Cai J, et al. Among authors: li w. Bioorg Med Chem Lett. 2024 Jun 1;105:129726. doi: 10.1016/j.bmcl.2024.129726. Epub 2024 Apr 3. Bioorg Med Chem Lett. 2024. PMID: 38580135

6

New Monocyclic, Bicyclic, and Tricyclic Ethynylcyanodienones as Activators of the Keap1/Nrf2/ARE Pathway and Inhibitors of Inducible Nitric Oxide Synthase.

Li W, Zheng S, Higgins M, Morra RP Jr, Mendis AT, Chien CW, Ojima I, Mierke DF, Dinkova-Kostova AT, Honda T. Li W, et al. J Med Chem. 2015 Jun 11;58(11):4738-48. doi: 10.1021/acs.jmedchem.5b00393. Epub 2015 May 20. J Med Chem. 2015. PMID: 25965897

7

Discovery of novel oridonin sulfamide derivatives as potent NLRP3 inhibitors by a visible-light photocatalysis-enabled peripheral editing.

Li M, Wang C, Ye S, Li W, Zhang Y, Yan J, Wang Y, Yang H, Wu Y, Zhang Y, Zhang H, Miao Z. Li M, et al. Among authors: li w. Bioorg Med Chem Lett. 2024 Feb 1;99:129621. doi: 10.1016/j.bmcl.2024.129621. Epub 2024 Jan 18. Bioorg Med Chem Lett. 2024. PMID: 38244941

8

Discovery and preclinical profile of YK-2168, a differentiated selective CDK9 inhibitor in clinical development.

Liu Y, Xu Z, Hu L, Xia L, Li Q, Zhou W, Chen Y, Li W, Jiang W, Zhu X, Gao X, Xia Y, Zhu Z, Chen S, Ding CZ. Liu Y, et al. Among authors: li w, li q. Bioorg Med Chem Lett. 2024 Nov 1;112:129941. doi: 10.1016/j.bmcl.2024.129941. Epub 2024 Sep 1. Bioorg Med Chem Lett. 2024. PMID: 39222890

9

Discovery and synthesis of novel glyrrhizin-analogs containing furanoylpiperazine and the activity against myocardial injury in sepsis.

Li W, Peng Y, Liu J, Wu T, Qiang X, Zhao Q, He D. Li W, et al. Bioorg Chem. 2024 Dec;153:107846. doi: 10.1016/j.bioorg.2024.107846. Epub 2024 Sep 24. Bioorg Chem. 2024. PMID: 39341082

10

Electron affinity of tricyclic, bicyclic, and monocyclic compounds containing cyanoenones correlates with their potency as inducers of a cytoprotective enzyme.

Bensasson RV, Dinkova-Kostova AT, Zheng S, Saito A, Li W, Zoete V, Honda T. Bensasson RV, et al. Among authors: li w. Bioorg Med Chem Lett. 2016 Sep 1;26(17):4345-9. doi: 10.1016/j.bmcl.2016.07.028. Epub 2016 Jul 15. Bioorg Med Chem Lett. 2016. PMID: 27460172

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