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Advancing precision therapy for colorectal cancer: Developing clinical indications for multi-target kinase inhibitor BPR1J481 using patient-derived xenograft models.
Tang YC, Ou JJ, Hsu SC, Huang CH, Lin LM, Chang HH, Wang YH, Huang ZT, Sun M, Liu KJ, Hung YM, Lai CY, Shih C, Chen CT, Chang JY, Hsieh HP, Jiaang WT, Kuo CC. Tang YC, et al. Pharmacol Res. 2025 Jan;211:107556. doi: 10.1016/j.phrs.2024.107556. Epub 2024 Dec 20. Pharmacol Res. 2025. PMID: 39709137 Free article.
4-Bromophenylhydrazinyl benzenesulfonylphenylureas as indoleamine 2,3-dioxygenase inhibitors with in vivo target inhibition and anti-tumor efficacy.
Lin SY, Yeh TK, Song JS, Hung MS, Cheng MF, Liao FY, Li AS, Cheng SY, Lin LM, Chiu CH, Wu MH, Lin YJ, Hsiao W, Sun M, Wang YH, Huang CH, Tang YC, Chang HH, Huang ZT, Chao YS, Shih C, Pan SL, Wu SY, Kuo CC, Ueng SH. Lin SY, et al. Among authors: tang yc. Bioorg Chem. 2018 Apr;77:600-607. doi: 10.1016/j.bioorg.2018.02.010. Epub 2018 Feb 12. Bioorg Chem. 2018. PMID: 29494816
Enhanced B-Raf-mediated NRF2 gene transcription and HATs-mediated NRF2 protein acetylation contributes to ABCC1-mediated chemoresistance and glutathione-mediated survival in acquired topoisomerase II poison-resistant cancer cells.
Chen HH, Chang HH, Chang JY, Tang YC, Cheng YC, Lin LM, Cheng SY, Huang CH, Sun MW, Chen CT, Kuo CC. Chen HH, et al. Among authors: tang yc. Free Radic Biol Med. 2017 Dec;113:505-518. doi: 10.1016/j.freeradbiomed.2017.10.375. Epub 2017 Nov 5. Free Radic Biol Med. 2017. PMID: 29080842
Development of Potent and Selective Inhibitors of Methylenetetrahydrofolate Dehydrogenase 2 for Targeting Acute Myeloid Leukemia: SAR, Structural Insights, and Biological Characterization.
Chang HH, Lee LC, Hsu T, Peng YH, Huang CH, Yeh TK, Lu CT, Huang ZT, Hsueh CC, Kung FC, Lin LM, Huang YC, Wang YH, Li LH, Tang YC, Chang L, Hsieh CC, Jiaang WT, Kuo CC, Wu SY. Chang HH, et al. Among authors: tang yc. J Med Chem. 2024 Dec 12;67(23):21106-21125. doi: 10.1021/acs.jmedchem.4c01775. Epub 2024 Nov 26. J Med Chem. 2024. PMID: 39591507 Free PMC article.
IL-1β promotes malignant transformation and tumor aggressiveness in oral cancer.
Lee CH, Chang JS, Syu SH, Wong TS, Chan JY, Tang YC, Yang ZP, Yang WC, Chen CT, Lu SC, Tang PH, Yang TC, Chu PY, Hsiao JR, Liu KJ. Lee CH, et al. Among authors: tang yc, tang ph. J Cell Physiol. 2015 Apr;230(4):875-84. doi: 10.1002/jcp.24816. J Cell Physiol. 2015. PMID: 25204733 Free article.
Endothelin-1 stimulates resistin gene expression.
Tang YC, Liu CW, Chang HH, Juan CC, Kuo YC, Kao CC, Huang YM, Kao YH. Tang YC, et al. Endocrinology. 2014 Mar;155(3):854-64. doi: 10.1210/en.2013-1847. Epub 2014 Jan 1. Endocrinology. 2014. PMID: 24424064
289 results