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A human-like glutaminase-free asparaginase is highly efficacious in ASNSlow leukemia and solid cancer mouse xenograft models.
Van Trimpont M, Schalk AM, Hofkens K, Peeters E, T'Sas S, Vandemeulebroecke K, Su Y, De Loera A, Garcia A, Chen H, Lammens T, Van Vlierberghe P, Goossens S, Lavie A. Van Trimpont M, et al. Among authors: vandemeulebroecke k. Cancer Lett. 2024 Dec 19:217404. doi: 10.1016/j.canlet.2024.217404. Online ahead of print. Cancer Lett. 2024. PMID: 39709177 Free article.
In vivo stabilization of a less toxic asparaginase variant leads to a durable antitumor response in acute leukemia.
Van Trimpont M, Schalk AM, De Visser Y, Nguyen HA, Reunes L, Vandemeulebroecke K, Peeters E, Su Y, Lee H, Lorenzi PL, Chan WK, Mondelaers V, De Moerloose B, Lammens T, Goossens S, Van Vlierberghe P, Lavie A. Van Trimpont M, et al. Among authors: vandemeulebroecke k. Haematologica. 2023 Feb 1;108(2):409-419. doi: 10.3324/haematol.2022.281390. Haematologica. 2023. PMID: 35979719 Free PMC article.
Prospective, real-time monitoring of pegylated Escherichia coli and Erwinia asparaginase therapy in childhood acute lymphoblastic leukaemia and non-Hodgkin lymphoma in Belgium.
Mondelaers V, Ferster A, Uyttebroeck A, Brichard B, van der Werff Ten Bosch J, Norga K, Francotte N, Piette C, Vandemeulebroecke K, Verbeke C, Schmidt S, Benoit Y, Lammens T, De Moerloose B. Mondelaers V, et al. Among authors: vandemeulebroecke k. Br J Haematol. 2020 Jul;190(1):105-114. doi: 10.1111/bjh.16495. Epub 2020 Feb 14. Br J Haematol. 2020. PMID: 32057100 Free article.
Transfer of Pantoea citrea, Pantoea punctata and Pantoea terrea to the genus Tatumella emend. as Tatumella citrea comb. nov., Tatumella punctata comb. nov. and Tatumella terrea comb. nov. and description of Tatumella morbirosei sp. nov.
Brady CL, Venter SN, Cleenwerck I, Vandemeulebroecke K, De Vos P, Coutinho TA. Brady CL, et al. Among authors: vandemeulebroecke k. Int J Syst Evol Microbiol. 2010 Mar;60(Pt 3):484-494. doi: 10.1099/ijs.0.012070-0. Epub 2009 Aug 4. Int J Syst Evol Microbiol. 2010. PMID: 19654354
39 results