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Page 1
Monoclonal antibodies targeting the FimH adhesin protect against uropathogenic E. coli UTI.
Lopatto EDB, Santiago-Borges JM, Sanick DA, Malladi SK, Azimzadeh PN, Timm MW, Fox IF, Schmitz AJ, Turner JS, Ahmed SS, Ortinau L, Gualberto NC, Pinkner JS, Dodson KW, Ellebedy AH, Kau AL, Hultgren SJ. Lopatto EDB, et al. Among authors: ellebedy ah. bioRxiv [Preprint]. 2024 Dec 11:2024.12.10.627638. doi: 10.1101/2024.12.10.627638. bioRxiv. 2024. PMID: 39713358 Free PMC article. Preprint.
Defining a highly conserved B cell epitope in the receptor binding motif of SARS-CoV-2 spike glycoprotein.
Malladi SK, Jaiswal D, Ying B, Alsoussi WB, Darling TL, Dadonaite B, Civljak A, Horvath SC, Zhou JQ, Kim W, Turner JS, Schmitz AJ, Han F, Scheaffer SM, Farnsworth CW, Nachbagauer R, Nestorova B, Chalkias S, Klebert MK, Edwards DK, Paris R, Strnad BS, Middleton WD, O'Halloran JA, Presti RM, Bloom JD, Boon ACM, Diamond MS, Bajic G, Ellebedy AH. Malladi SK, et al. Among authors: ellebedy ah. bioRxiv [Preprint]. 2024 Dec 9:2024.12.06.625234. doi: 10.1101/2024.12.06.625234. bioRxiv. 2024. PMID: 39713327 Free PMC article. Preprint.
Protective effect and molecular mechanisms of human non-neutralizing cross-reactive spike antibodies elicited by SARS-CoV-2 mRNA vaccination.
Clark JJ, Hoxie I, Adelsberg DC, Sapse IA, Andreata-Santos R, Yong JS, Amanat F, Tcheou J, Raskin A, Singh G, González-Domínguez I, Edgar JE, Bournazos S, Sun W, Carreño JM, Simon V, Ellebedy AH, Bajic G, Krammer F. Clark JJ, et al. Among authors: ellebedy ah. Cell Rep. 2024 Nov 26;43(11):114922. doi: 10.1016/j.celrep.2024.114922. Epub 2024 Nov 5. Cell Rep. 2024. PMID: 39504245 Free article.
mRNA-based influenza vaccine expands breadth of B cell response in humans.
Matz HC, Yu TG, Zhou JQ, Peyton L, Madsen A, Han F, Schmitz AJ, Horvath SC, Dixit K, Keplinger HK, Strnad BS, Hoegger MJ, Middleton WD, Klebert MK, Lin NH, Nachbagauer R, Paris R, Turner JS, Presti RM, Lee J, Ellebedy AH. Matz HC, et al. Among authors: ellebedy ah. bioRxiv [Preprint]. 2024 Oct 13:2024.10.10.617255. doi: 10.1101/2024.10.10.617255. bioRxiv. 2024. PMID: 39416092 Free PMC article. Preprint.
Repeat modules and N-linked glycans define structure and antigenicity of a critical enterotoxigenic E. coli adhesin.
Berndsen ZT, Akhtar M, Thapa M, Vickers TJ, Schmitz A, Torres JL, Baboo S, Kumar P, Khatoon N, Sheikh A, Hamrick M, Diedrich JK, Martinez-Bartolome S, Garrett PT, Yates JR 3rd, Turner JS, Laird RM, Poly F, Porter CK, Copps J, Ellebedy AH, Ward AB, Fleckenstein JM. Berndsen ZT, et al. Among authors: ellebedy ah. PLoS Pathog. 2024 Sep 16;20(9):e1012241. doi: 10.1371/journal.ppat.1012241. eCollection 2024 Sep. PLoS Pathog. 2024. PMID: 39283948 Free PMC article.
CD4+ T cells exhibit distinct transcriptional phenotypes in the lymph nodes and blood following mRNA vaccination in humans.
Borcherding N, Kim W, Quinn M, Han F, Zhou JQ, Sturtz AJ, Schmitz AJ, Lei T, Schattgen SA, Klebert MK, Suessen T, Middleton WD, Goss CW, Liu C, Crawford JC, Thomas PG, Teefey SA, Presti RM, O'Halloran JA, Turner JS, Ellebedy AH, Mudd PA. Borcherding N, et al. Among authors: ellebedy ah. Nat Immunol. 2024 Sep;25(9):1731-1741. doi: 10.1038/s41590-024-01888-9. Epub 2024 Aug 20. Nat Immunol. 2024. PMID: 39164479
Influenza vaccination stimulates maturation of the human T follicular helper cell response.
Schattgen SA, Turner JS, Ghonim MA, Crawford JC, Schmitz AJ, Kim H, Zhou JQ, Awad W, Mettelman RC, Kim W, McIntire KM, Haile A, Klebert MK, Suessen T, Middleton WD, Teefey SA, Presti RM, Ellebedy AH, Thomas PG. Schattgen SA, et al. Among authors: ellebedy ah. Nat Immunol. 2024 Sep;25(9):1742-1753. doi: 10.1038/s41590-024-01926-6. Epub 2024 Aug 20. Nat Immunol. 2024. PMID: 39164477 Free PMC article.
Receptor Binding Specificity of a Bovine A(H5N1) Influenza Virus.
Chopra P, Page CK, Shepard JD, Ray SD, Kandeil A, Jeevan T, Bowman AS, Ellebedy AH, Webby RJ, de Vries RP, Tompkins SM, Boons GJ. Chopra P, et al. Among authors: ellebedy ah. bioRxiv [Preprint]. 2024 Jul 31:2024.07.30.605893. doi: 10.1101/2024.07.30.605893. bioRxiv. 2024. PMID: 39131339 Free PMC article. Preprint.
Maturation of germinal center B cells after influenza virus vaccination in humans.
McIntire KM, Meng H, Lin TH, Kim W, Moore NE, Han J, McMahon M, Wang M, Malladi SK, Mohammed BM, Zhou JQ, Schmitz AJ, Hoehn KB, Carreño JM, Yellin T, Suessen T, Middleton WD, Teefey SA, Presti RM, Krammer F, Turner JS, Ward AB, Wilson IA, Kleinstein SH, Ellebedy AH. McIntire KM, et al. Among authors: ellebedy ah. J Exp Med. 2024 Aug 5;221(8):e20240668. doi: 10.1084/jem.20240668. Epub 2024 Jun 27. J Exp Med. 2024. PMID: 38935072
106 results