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Ethanol self-administration targets GluA2-containing AMPA receptor expression and synaptic activity in the nucleus accumbens in a manner that drives the positive reinforcing properties of the drug.
Faccidomo S, Saunders BL, May AM, Eastman VR, Kim M, Taylor SM, Hoffman JL, McElligott ZA, Hodge CW. Faccidomo S, et al. Among authors: taylor sm. Psychopharmacology (Berl). 2024 Dec 23. doi: 10.1007/s00213-024-06740-4. Online ahead of print. Psychopharmacology (Berl). 2024. PMID: 39714485
Inhibition of AMPA receptors (AMPARs) containing transmembrane AMPAR regulatory protein γ-8 with JNJ-55511118 shows preclinical efficacy in reducing chronic repetitive alcohol self-administration.
Hoffman JL, Faccidomo S, Saunders BL, Taylor SM, Kim M, Hodge CW. Hoffman JL, et al. Among authors: taylor sm. Alcohol Clin Exp Res. 2021 Jul;45(7):1424-1435. doi: 10.1111/acer.14639. Epub 2021 Jun 22. Alcohol Clin Exp Res. 2021. PMID: 34086361 Free PMC article.
Negative modulation of AMPA receptors bound to transmembrane AMPA receptor regulatory protein γ-8 blunts the positive reinforcing properties of alcohol and sucrose in a brain region-dependent manner in male mice.
Hoffman JL, Faccidomo SP, Taylor SM, DeMiceli KG, May AM, Smith EN, Whindleton CM, Hodge CW. Hoffman JL, et al. Among authors: taylor sm. Psychopharmacology (Berl). 2023 Jun;240(6):1261-1273. doi: 10.1007/s00213-023-06365-z. Epub 2023 Apr 13. Psychopharmacology (Berl). 2023. PMID: 37055596 Free PMC article.
Operant alcohol self-administration targets GluA2-containing AMPA receptor expression and synaptic activity in the nucleus accumbens in a manner that drives the positive reinforcing properties of the drug.
Faccidomo S, Saunders BL, May AM, Eastman VR, Kim M, Taylor SM, Hoffman JL, McElligott ZA, Hodge CW. Faccidomo S, et al. Among authors: taylor sm. bioRxiv [Preprint]. 2024 Nov 14:2024.09.13.612946. doi: 10.1101/2024.09.13.612946. bioRxiv. 2024. Update in: Psychopharmacology (Berl). 2024 Dec 23. doi: 10.1007/s00213-024-06740-4 PMID: 39314444 Free PMC article. Updated. Preprint.
Effects on maternal and pregnancy outcomes of first-trimester malaria infection among nulliparous women from Kenya, Zambia, and the Democratic Republic of the Congo.
Leuba SI, Westreich D, Bose CL, Olshan AF, Taylor SM, Tshefu A, Lokangaka A, Carlo WA, Chomba E, Mwenechanya M, Liechty EA, Bucher SL, Ekhaguere OA, Esamai F, Nyongesa P, Jessani S, Saleem S, Goldenberg RL, Moore JL, Nolen TL, Hemingway-Foday J, McClure EM, Koso-Thomas M, Derman RJ, Hoffman M, Meshnick SR, Bauserman M. Leuba SI, et al. Among authors: taylor sm. PLoS One. 2024 Dec 20;19(12):e0310339. doi: 10.1371/journal.pone.0310339. eCollection 2024. PLoS One. 2024. PMID: 39705264 Free PMC article.
861 results