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Thiazole-based IL-17 inhibitors discovered by scaffold morphing.
Velcicky J, Ngo E, Bauer MR, Meyer A, Schlapbach A, Racine S, Orain D, Pflieger D, Teixeira-Fouchard S, Dubois C, Goetz A, Steiner R, Palmieri M, Bussenault A, Stringer R, Larger P, Riek S, Schmutz P, Lehmann S, Scheufler C, Rondeau JM, Burkhart C, Knoepfel T, Gommermann N. Velcicky J, et al. Among authors: schmutz p. ChemMedChem. 2024 Dec 23:e202400851. doi: 10.1002/cmdc.202400851. Online ahead of print. ChemMedChem. 2024. PMID: 39715021
Discovery and In Vivo Exploration of 1,3,4-Oxadiazole and α-Fluoroacrylate Containing IL-17 Inhibitors.
Velcicky J, Bauer MR, Schlapbach A, Lapointe G, Meyer A, Vögtle M, Blum E, Ngo E, Rolando C, Nimsgern P, Teixeira-Fouchard S, Lehmann H, Furet P, Berst F, Schümann J, Stringer R, Larger P, Schmid C, Prendergast CT, Riek S, Schmutz P, Lehmann S, Berghausen J, Scheufler C, Rondeau JM, Burkhart C, Knoepfel T, Gommermann N. Velcicky J, et al. Among authors: schmutz p. J Med Chem. 2024 Sep 26;67(18):16692-16711. doi: 10.1021/acs.jmedchem.4c01520. Epub 2024 Sep 14. J Med Chem. 2024. PMID: 39276085
Bio-Inspired Micro- and Nano-Scale Surface Features Produced by Femtosecond Laser-Texturing Enhance TiZr-Implant Osseointegration.
Lackington WA, Bellon B, Guimond S, Schweizer P, Cancellieri C, Ambeza A, Chopard-Lallier AL, Pippenger B, Armutlulu A, Maeder X, Schmutz P, Rottmar M. Lackington WA, et al. Among authors: schmutz p. Adv Healthc Mater. 2024 Sep;13(23):e2400810. doi: 10.1002/adhm.202400810. Epub 2024 Jun 21. Adv Healthc Mater. 2024. PMID: 38857489
Two Steady-State Adsorption Modes of Phosphonic Acids on Aluminum Surfaces.
Zhao R, Schmutz P, Jeurgens LPH, Chen J, Gooneie A, Ott N, Gaan S, Heuberger M. Zhao R, et al. Among authors: schmutz p. ACS Appl Mater Interfaces. 2022 Aug 31;14(34):39467-39477. doi: 10.1021/acsami.2c07128. Epub 2022 Aug 22. ACS Appl Mater Interfaces. 2022. PMID: 35994435
44 results