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Page 1
Thoughts for the future.
Alkhalaf LM, Arrowsmith C, Balskus EP, Bergamini G, Bhandari R, Chang CJ, Chen P, Chen X, Ciulli A, Cricco JA, Davis BG, Delbianco M, Dudareva N, Dueber E, Ferguson F, de Giuseppe PO, Hamachi I, Hammond MC, Hatzios SK, Do Heo W, Janet JP, Kamat SS, Knapp S, Krishnan Y, Lang K, Laraia L, Leveson-Gower RB, Li XD, Liu DR, Liu MF, London N, Mahanta N, Mayor-Ruiz C, Muir T, Murakami MT, Rhee HW, Robers M, Satz A, Schulman BA, Shen B, Shoichet B, Strauss E, Suzuki T, Tiwary P, Waldmann H, Ward TR, Weeks A, Weerapana E, Winter G. Alkhalaf LM, et al. Among authors: ferguson f. Nat Chem Biol. 2025 Jan;21(1):6-15. doi: 10.1038/s41589-024-01802-2. Nat Chem Biol. 2025. PMID: 39719500 No abstract available.
A Kinetic Scout Approach Accelerates Targeted Protein Degrader Development.
Fan AT, Gadbois GE, Huang HT, Chaudhry C, Jiang J, Sigua LH, Smith ER, Wu S, Poirier GJ, Dunne-Dombrink K, Goyal P, Tao AJ, Sellers WR, Fischer ES, Donovan KA, Ferguson FM. Fan AT, et al. Among authors: ferguson fm. Angew Chem Int Ed Engl. 2024 Nov 27:e202417272. doi: 10.1002/anie.202417272. Online ahead of print. Angew Chem Int Ed Engl. 2024. PMID: 39602499
A Kinetic Scout Approach Accelerates Targeted Protein Degrader Development.
Fan AT, Gadbois GE, Huang HT, Jiang J, Sigua LH, Smith ER, Wu S, Dunne-Dombrink K, Goyal P, Tao AJ, Sellers W, Fischer ES, Donovan KA, Ferguson FM. Fan AT, et al. Among authors: ferguson fm. bioRxiv [Preprint]. 2024 Sep 21:2024.09.17.612508. doi: 10.1101/2024.09.17.612508. bioRxiv. 2024. Update in: Angew Chem Int Ed Engl. 2024 Nov 27:e202417272. doi: 10.1002/anie.202417272 PMID: 39345570 Free PMC article. Updated. Preprint.
DCLK1 induces a pro-tumorigenic phenotype to drive gastric cancer progression.
Afshar-Sterle S, Carli ALE, O'Keefe R, Tse J, Fischer S, Azimpour AI, Baloyan D, Elias L, Thilakasiri P, Patel O, Ferguson FM, Eissmann MF, Chand AL, Gray NS, Busuttil R, Boussioutas A, Lucet IS, Ernst M, Buchert M. Afshar-Sterle S, et al. Among authors: ferguson fm. Sci Signal. 2024 Sep 17;17(854):eabq4888. doi: 10.1126/scisignal.abq4888. Epub 2024 Sep 17. Sci Signal. 2024. PMID: 39288218
Making transient complexes stick.
Wang Y, Mouli MSSV, Ma M, Ferguson FM. Wang Y, et al. Among authors: ferguson fm. Nat Chem Biol. 2024 Dec;20(12):1557-1558. doi: 10.1038/s41589-024-01649-7. Nat Chem Biol. 2024. PMID: 39075251 No abstract available.
Pan-RAF:MEK Molecular Glues Take Center Stage.
Hangauer MJ, Gutkind JS, Ferguson FM. Hangauer MJ, et al. Among authors: ferguson fm. Cancer Discov. 2024 Jul 1;14(7):1143-1144. doi: 10.1158/2159-8290.CD-24-0539. Cancer Discov. 2024. PMID: 38946324
Application of induced proximity for therapeutic discovery.
Cacace A, Daniels D, Ferguson FM, Mayor-Ruiz C, Woo C. Cacace A, et al. Among authors: ferguson fm. Cell Chem Biol. 2024 Jun 20;31(6):1036-1038. doi: 10.1016/j.chembiol.2024.05.015. Cell Chem Biol. 2024. PMID: 38906107
253 results