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Engineered protein subunit COVID19 vaccine is as immunogenic as nanoparticles in mouse and hamster models.
Matthews MM, Kim TG, Kim KY, Meshcheryakov V, Iha HA, Tamai M, Sasaki D, Laurino P, Toledo-Patiño S, Collins M, Hsieh TY, Shibata S, Shibata N, Obata F, Fujii J, Ito T, Ito H, Ishikawa H, Wolf M. Matthews MM, et al. Among authors: obata f. Sci Rep. 2024 Oct 26;14(1):25528. doi: 10.1038/s41598-024-76377-y. Sci Rep. 2024. PMID: 39462119 Free PMC article.
Genetic engineering employing MPB70 and its promoter enables efficient secretion and expression of foreign antigen in bacillus Calmette Guérin (BCG) Tokyo.
Takeishi A, Shaban AK, Kakihana T, Takihara H, Okuda S, Osada H, Suameitria Dewi DNS, Ozeki Y, Yoshida Y, Nishiyama A, Tateishi Y, Aizu Y, Chuma Y, Onishi K, Hayashi D, Yamamoto S, Mukai T, Ato M, Thai DH, Nhi HTT, Shirai T, Shibata S, Obata F, Fujii J, Yamayoshi S, Kiso M, Matsumoto S. Takeishi A, et al. Among authors: obata f. Microbiol Immunol. 2024 Apr;68(4):130-147. doi: 10.1111/1348-0421.13116. Epub 2024 Jan 31. Microbiol Immunol. 2024. PMID: 38294180
165 results