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MIRO2 promotes cancer invasion and metastasis via MYO9B suppression of RhoA activity.
Boulton DP, Hughes CJ, Vaira V, Del Gobbo A, Palleschi A, Locatelli M, Danis E, Raza M, Neumann AJ, Purdy SC, Lerma R, Meshki J, Ford HL, Prekeris R, Morrissey C, Caino MC. Boulton DP, et al. Among authors: vaira v. Cell Rep. 2024 Dec 24;44(1):115120. doi: 10.1016/j.celrep.2024.115120. Online ahead of print. Cell Rep. 2024. PMID: 39723893 Free article.
Mitochondrial Akt Regulation of Hypoxic Tumor Reprogramming.
Chae YC, Vaira V, Caino MC, Tang HY, Seo JH, Kossenkov AV, Ottobrini L, Martelli C, Lucignani G, Bertolini I, Locatelli M, Bryant KG, Ghosh JC, Lisanti S, Ku B, Bosari S, Languino LR, Speicher DW, Altieri DC. Chae YC, et al. Among authors: vaira v. Cancer Cell. 2016 Aug 8;30(2):257-272. doi: 10.1016/j.ccell.2016.07.004. Cancer Cell. 2016. PMID: 27505672 Free PMC article.
A new mouse avatar model of non-small cell lung cancer.
Russo MV, Faversani A, Gatti S, Ricca D, Del Gobbo A, Ferrero S, Palleschi A, Vaira V, Bosari S. Russo MV, et al. Among authors: vaira v. Front Oncol. 2015 Mar 3;5:52. doi: 10.3389/fonc.2015.00052. eCollection 2015. Front Oncol. 2015. PMID: 25785245 Free PMC article.
A neuronal network of mitochondrial dynamics regulates metastasis.
Caino MC, Seo JH, Aguinaldo A, Wait E, Bryant KG, Kossenkov AV, Hayden JE, Vaira V, Morotti A, Ferrero S, Bosari S, Gabrilovich DI, Languino LR, Cohen AR, Altieri DC. Caino MC, et al. Among authors: vaira v. Nat Commun. 2016 Dec 19;7:13730. doi: 10.1038/ncomms13730. Nat Commun. 2016. PMID: 27991488 Free PMC article.
Ghost mitochondria drive metastasis through adaptive GCN2/Akt therapeutic vulnerability.
Ghosh JC, Perego M, Agarwal E, Bertolini I, Wang Y, Goldman AR, Tang HY, Kossenkov AV, Landis CJ, Languino LR, Plow EF, Morotti A, Ottobrini L, Locatelli M, Speicher DW, Caino MC, Cassel J, Salvino JM, Robert ME, Vaira V, Altieri DC. Ghosh JC, et al. Among authors: vaira v. Proc Natl Acad Sci U S A. 2022 Feb 22;119(8):e2115624119. doi: 10.1073/pnas.2115624119. Proc Natl Acad Sci U S A. 2022. PMID: 35177476 Free PMC article.
PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion.
Caino MC, Ghosh JC, Chae YC, Vaira V, Rivadeneira DB, Faversani A, Rampini P, Kossenkov AV, Aird KM, Zhang R, Webster MR, Weeraratna AT, Bosari S, Languino LR, Altieri DC. Caino MC, et al. Among authors: vaira v. Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):8638-43. doi: 10.1073/pnas.1500722112. Epub 2015 Jun 29. Proc Natl Acad Sci U S A. 2015. PMID: 26124089 Free PMC article.
118 results