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Ketamine impairs the performance of male mice in novel recognition object test and reduces the immunoreactivity of GAD67 in the hippocampus: Role of pioglitazone.
Rodrigues T, Bressan GN, Juliani PZ, da Silva MEB, Fachinetto R. Rodrigues T, et al. Pharmacol Biochem Behav. 2024 Dec 24:173950. doi: 10.1016/j.pbb.2024.173950. Online ahead of print. Pharmacol Biochem Behav. 2024. PMID: 39725040
We investigated the effects of pioglitazone, an agonist of PPAR-gamma, on the behavioral alterations induced by ketamine and, whether alterations in monoamine oxidase (MAO) activity, glutamic acid decarboxylase (GAD(67)), PPAR-gamma or tyrosine hydroxylase (TH) immu …
We investigated the effects of pioglitazone, an agonist of PPAR-gamma, on the behavioral alterations induced by ketamine and, whether altera …
Network Pharmacology and Metabolomics Reveal Anti-Ferroptotic Effects of Curcumin in Acute Kidney Injury.
Liu X, Zhou Y, Lu Z, Yang F, Wang Y, Zhang S, Zhang J, Zou H, Lin M. Liu X, et al. Drug Des Devel Ther. 2024 Dec 21;18:6223-6241. doi: 10.2147/DDDT.S486286. eCollection 2024. Drug Des Devel Ther. 2024. PMID: 39722679 Free PMC article.
Evidences suggest that ferroptosis is the primary cause of AKI, while inhibition of monoamine oxidase A(MAOA) and 5-hydroxytryptamine were recognized as the defender of ferroptosis. ...
Evidences suggest that ferroptosis is the primary cause of AKI, while inhibition of monoamine oxidase A(MAOA) and 5-hydroxytry …
Recent advances in potential enzymes and their therapeutic inhibitors for the treatment of Alzheimer's disease.
Vahid ZF, Eskandani M, Dadashi H, Vandghanooni S, Rashidi MR. Vahid ZF, et al. Heliyon. 2024 Nov 28;10(23):e40756. doi: 10.1016/j.heliyon.2024.e40756. eCollection 2024 Dec 15. Heliyon. 2024. PMID: 39717593 Free PMC article. Review.
In this review, the molecular mechanisms involved in the pathogenesis of AD were overviewed and various enzymes such as acetylcholinesterase (AChE), butyrylcholinesterase (BuChE), beta-secretase, gamma-secretase, monoamine oxidase (MAO), and receptor of advanced gly …
In this review, the molecular mechanisms involved in the pathogenesis of AD were overviewed and various enzymes such as acetylcholinesterase …
Surface-enhanced Raman spectroscopy: a half-century historical perspective.
Yi J, You EM, Hu R, Wu DY, Liu GK, Yang ZL, Zhang H, Gu Y, Wang YH, Wang X, Ma H, Yang Y, Liu JY, Fan FR, Zhan C, Tian JH, Qiao Y, Wang H, Luo SH, Meng ZD, Mao BW, Li JF, Ren B, Aizpurua J, Apkarian VA, Bartlett PN, Baumberg J, Bell SEJ, Brolo AG, Brus LE, Choo J, Cui L, Deckert V, Domke KF, Dong ZC, Duan S, Faulds K, Frontiera R, Halas N, Haynes C, Itoh T, Kneipp J, Kneipp K, Le Ru EC, Li ZP, Ling XY, Lipkowski J, Liz-Marzán LM, Nam JM, Nie S, Nordlander P, Ozaki Y, Panneerselvam R, Popp J, Russell AE, Schlücker S, Tian Y, Tong L, Xu H, Xu Y, Yang L, Yao J, Zhang J, Zhang Y, Zhang Y, Zhao B, Zenobi R, Schatz GC, Graham D, Tian ZQ. Yi J, et al. Chem Soc Rev. 2024 Dec 23. doi: 10.1039/d4cs00883a. Online ahead of print. Chem Soc Rev. 2024. PMID: 39715320 Review.
The highs and lows of monoamine oxidase as molecular target in cancer: an updated review.
Hâncu IM, Giuchici S, Furdui-Lința AV, Lolescu B, Sturza A, Muntean DM, Dănilă MD, Lighezan R. Hâncu IM, et al. Mol Cell Biochem. 2024 Dec 23. doi: 10.1007/s11010-024-05192-w. Online ahead of print. Mol Cell Biochem. 2024. PMID: 39714760 Review.
The global burden of cancer as a major cause of death and invalidity has been constantly increasing in the past decades. Monoamine oxidases (MAO) with two isoforms, MAO-A and MAO-B, are mammalian mitochondrial enzymes responsible for the oxidative deamination …
The global burden of cancer as a major cause of death and invalidity has been constantly increasing in the past decades. Monoamine ox …
Parkia biglobosa Jacq. (Locust Bean) leaves and seeds extracts attenuates diabetic-linked cognitive dysfunction in streptozotocin-induced male wistar rats.
Ajiboye OM, Ogunwenmo KO, Adewumi AG, Mohanye CC. Ajiboye OM, et al. Metab Brain Dis. 2024 Dec 23;40(1):76. doi: 10.1007/s11011-024-01514-5. Metab Brain Dis. 2024. PMID: 39714608
Additionally, PB extracts significantly increased catalase (CAT) and superoxide dismutase (SOD) activities, reversing the diabetes-induced decline in antioxidant enzyme levels. Monoamine oxidase (MAO) activity, elevated in diabetic conditions, was significantly down …
Additionally, PB extracts significantly increased catalase (CAT) and superoxide dismutase (SOD) activities, reversing the diabetes-induced d …
Effectiveness of pharmacological therapies for fibromyalgia syndrome in adults: an overview of Cochrane Reviews.
Moore A, Bidonde J, Fisher E, Häuser W, Bell RF, Perrot S, Makri S, Straube S. Moore A, et al. Rheumatology (Oxford). 2024 Dec 23:keae708. doi: 10.1093/rheumatology/keae708. Online ahead of print. Rheumatology (Oxford). 2024. PMID: 39714260
Seven reviews found no trials (carbamazepine, clonazepam, lamotrigine, phenytoin, oxycodone, topiramate, or valproate), seven had limited and inadequate data (antipsychotics, cannabinoids, combination therapy, gabapentin, lacosamide, monoamine oxidase inhibitors, NS …
Seven reviews found no trials (carbamazepine, clonazepam, lamotrigine, phenytoin, oxycodone, topiramate, or valproate), seven had limited an …
27,388 results
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