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G3BP-driven RNP granules promote inhibitory RNA-RNA interactions resolved by DDX3X to regulate mRNA translatability.
Trussina IREA, Hartmann A, Desroches Altamirano C, Natarajan J, Fischer CM, Aleksejczuk M, Ausserwöger H, Knowles TPJ, Schlierf M, Franzmann TM, Alberti S. Trussina IREA, et al. Among authors: alberti s. Mol Cell. 2024 Dec 19:S1097-2765(24)00994-8. doi: 10.1016/j.molcel.2024.11.039. Online ahead of print. Mol Cell. 2024. PMID: 39729994 Free article.
RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation.
Guillén-Boixet J, Kopach A, Holehouse AS, Wittmann S, Jahnel M, Schlüßler R, Kim K, Trussina IREA, Wang J, Mateju D, Poser I, Maharana S, Ruer-Gruß M, Richter D, Zhang X, Chang YT, Guck J, Honigmann A, Mahamid J, Hyman AA, Pappu RV, Alberti S, Franzmann TM. Guillén-Boixet J, et al. Among authors: alberti s. Cell. 2020 Apr 16;181(2):346-361.e17. doi: 10.1016/j.cell.2020.03.049. Cell. 2020. PMID: 32302572 Free PMC article.
eIF4F is a thermo-sensing regulatory node in the translational heat shock response.
Desroches Altamirano C, Kang MK, Jordan MA, Borianne T, Dilmen I, Gnädig M, von Appen A, Honigmann A, Franzmann TM, Alberti S. Desroches Altamirano C, et al. Among authors: alberti s. Mol Cell. 2024 May 2;84(9):1727-1741.e12. doi: 10.1016/j.molcel.2024.02.038. Epub 2024 Mar 27. Mol Cell. 2024. PMID: 38547866 Free article.
Protein Phase Separation as a Stress Survival Strategy.
Franzmann TM, Alberti S. Franzmann TM, et al. Among authors: alberti s. Cold Spring Harb Perspect Biol. 2019 Jun 3;11(6):a034058. doi: 10.1101/cshperspect.a034058. Cold Spring Harb Perspect Biol. 2019. PMID: 30617047 Free PMC article. Review.
Condensation of Ded1p Promotes a Translational Switch from Housekeeping to Stress Protein Production.
Iserman C, Desroches Altamirano C, Jegers C, Friedrich U, Zarin T, Fritsch AW, Mittasch M, Domingues A, Hersemann L, Jahnel M, Richter D, Guenther UP, Hentze MW, Moses AM, Hyman AA, Kramer G, Kreysing M, Franzmann TM, Alberti S. Iserman C, et al. Among authors: alberti s. Cell. 2020 May 14;181(4):818-831.e19. doi: 10.1016/j.cell.2020.04.009. Epub 2020 Apr 30. Cell. 2020. PMID: 32359423 Free PMC article.
Phase-separating RNA-binding proteins form heterogeneous distributions of clusters in subsaturated solutions.
Kar M, Dar F, Welsh TJ, Vogel LT, Kühnemuth R, Majumdar A, Krainer G, Franzmann TM, Alberti S, Seidel CAM, Knowles TPJ, Hyman AA, Pappu RV. Kar M, et al. Among authors: alberti s. Proc Natl Acad Sci U S A. 2022 Jul 12;119(28):e2202222119. doi: 10.1073/pnas.2202222119. Epub 2022 Jul 5. Proc Natl Acad Sci U S A. 2022. PMID: 35787038 Free PMC article.
488 results