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Page 1
Coupling of response biomarkers between tumor and peripheral blood in patients undergoing chemoimmunotherapy.
Chin WL, Cook AM, Chee J, Principe N, Hoang TS, Kidman J, Hmon KPW, Yeow Y, Jones ME, Hou R, Denisenko E, McDonnell AM, Hon CC, Moody J, Anderson D, Yip S, Cummins MM, Stockler MR, Kok PS, Brown C, John T, Kao SC, Karikios DJ, O'Byrne KJ, Hughes BGM, Lake RA, Forrest ARR, Nowak AK, Lassmann T, Lesterhuis WJ. Chin WL, et al. Among authors: principe n. Cell Rep Med. 2024 Dec 18:101882. doi: 10.1016/j.xcrm.2024.101882. Online ahead of print. Cell Rep Med. 2024. PMID: 39731918 Free article.
CD4+ T cells drive an inflammatory, TNF-α/IFN-rich tumor microenvironment responsive to chemotherapy.
Tilsed CM, Principe N, Kidman J, Chin WL, Orozco Morales ML, Zemek RM, Chee J, Islam R, Fear VS, Forbes C, Aston WJ, Jansen M, Chopra A, Lassmann T, Nowak AK, Fisher SA, Lake RA, Lesterhuis WJ. Tilsed CM, et al. Among authors: principe n. Cell Rep. 2022 Dec 27;41(13):111874. doi: 10.1016/j.celrep.2022.111874. Cell Rep. 2022. PMID: 36577370 Free article.
Anti-metabolite chemotherapy increases LAG-3 expressing tumor-infiltrating lymphocytes which can be targeted by combination immune checkpoint blockade.
Principe N, Phung AL, Stevens KLP, Elaskalani O, Wylie B, Tilsed CM, Sheikh F, Orozco Morales ML, Kidman J, Marcq E, Fisher SA, Nowak AK, McDonnell AM, Lesterhuis WJ, Chee J. Principe N, et al. J Immunother Cancer. 2024 Sep 28;12(9):e008568. doi: 10.1136/jitc-2023-008568. J Immunother Cancer. 2024. PMID: 39343508 Free PMC article.
Immune checkpoint therapy responders display early clonal expansion of tumor infiltrating lymphocytes.
Kidman J, Zemek RM, Sidhom JW, Correa D, Principe N, Sheikh F, Fear VS, Forbes CA, Chopra A, Boon L, Zaitouny A, de Jong E, Holt RA, Jones M, Millward MJ, Lassmann T, Forrest ARR, Nowak AK, Watson M, Lake RA, Lesterhuis WJ, Chee J. Kidman J, et al. Among authors: principe n. Oncoimmunology. 2024 Apr 26;13(1):2345859. doi: 10.1080/2162402X.2024.2345859. eCollection 2024. Oncoimmunology. 2024. PMID: 38686178 Free PMC article.
Interferons limit autoantigen-specific CD8+ T-cell expansion in the non-obese diabetic mouse.
Jhala G, Krishnamurthy B, Brodnicki TC, Ge T, Akazawa S, Selck C, Trivedi PM, Pappas EG, Mackin L, Principe N, Brémaud E, De George DJ, Boon L, Smyth I, Chee J, Kay TWH, Thomas HE. Jhala G, et al. Among authors: principe n. Cell Rep. 2022 Apr 26;39(4):110747. doi: 10.1016/j.celrep.2022.110747. Cell Rep. 2022. PMID: 35476975 Free article.
26 results