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Page 1
Cyclic Ruthenium-Peptide Prodrugs Penetrate the Blood-Brain Barrier and Attack Glioblastoma upon Light Activation in Orthotopic Zebrafish Tumor Models.
Zhang L, Zhao G, Dalrymple T, Husiev Y, Bronkhorst H, Forn-Cuní G, Lopes-Bastos B, Snaar-Jagalska E, Bonnet S. Zhang L, et al. Among authors: husiev y. ACS Cent Sci. 2024 Dec 9;10(12):2294-2311. doi: 10.1021/acscentsci.4c01173. eCollection 2024 Dec 25. ACS Cent Sci. 2024. PMID: 39735314 Free PMC article.
Oxygen-Dependent Interactions between the Ruthenium Cage and the Photoreleased Inhibitor in NAMPT-Targeted Photoactivated Chemotherapy.
Abyar S, Huang L, Husiev Y, Bretin L, Chau B, Ramu V, Wildeman JH, Belfor K, Wijaya LS, van der Noord VE, Harms AC, Siegler MA, Le Dévédec SE, Bonnet S. Abyar S, et al. Among authors: husiev y. J Med Chem. 2024 Jul 11;67(13):11086-11102. doi: 10.1021/acs.jmedchem.4c00589. Epub 2024 Jun 26. J Med Chem. 2024. PMID: 38924492 Free PMC article.
A Lock-and-Kill Anticancer Photoactivated Chemotherapy Agent.
van Geest EP, Götzfried SK, Klein DM, Salitra N, Popal S, Husiev Y, Van der Griend CJ, Zhou X, Siegler MA, Schneider GF, Bonnet S. van Geest EP, et al. Among authors: husiev y. Photochem Photobiol. 2023 Mar;99(2):777-786. doi: 10.1111/php.13738. Epub 2022 Dec 1. Photochem Photobiol. 2023. PMID: 36315051
Photosubstitution in a trisheteroleptic ruthenium complex inhibits conjunctival melanoma growth in a zebrafish orthotopic xenograft model.
Chen Q, Cuello-Garibo JA, Bretin L, Zhang L, Ramu V, Aydar Y, Batsiun Y, Bronkhorst S, Husiev Y, Beztsinna N, Chen L, Zhou XQ, Schmidt C, Ott I, Jager MJ, Brouwer AM, Snaar-Jagalska BE, Bonnet S. Chen Q, et al. Among authors: husiev y. Chem Sci. 2022 May 16;13(23):6899-6919. doi: 10.1039/d2sc01646j. eCollection 2022 Jun 15. Chem Sci. 2022. PMID: 35774173 Free PMC article.