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Novel Naphthyridones Targeting Pannexin 1 for Colitis Management.
Hsueh WY, Wu YL, Weng MT, Liu SY, Santavanond JP, Liu YC, Lin CI, Lai CN, Lu YR, Hsu JY, Gao HY, Lee JC, Wei SC, Lyu PC, Poon IKH, Hsieh HP, Chiu YH. Hsueh WY, et al. Among authors: poon ikh. Adv Sci (Weinh). 2024 Dec 30:e2411538. doi: 10.1002/advs.202411538. Online ahead of print. Adv Sci (Weinh). 2024. PMID: 39739600
The small molecule raptinal can simultaneously induce apoptosis and inhibit PANX1 activity.
Santavanond JP, Chiu YH, Tixeira R, Liu Z, Yap JKY, Chen KW, Li CL, Lu YR, Roncero-Carol J, Hoijman E, Rutter SF, Shi B, Ryan GF, Hodge AL, Caruso S, Baxter AA, Ozkocak DC, Johnson C, Day ZI, Mayfosh AJ, Hulett MD, Phan TK, Atkin-Smith GK, Poon IKH. Santavanond JP, et al. Among authors: poon ikh. Cell Death Dis. 2024 Feb 9;15(2):123. doi: 10.1038/s41419-024-06513-z. Cell Death Dis. 2024. PMID: 38336804 Free PMC article.
Pannexin 1 Channels as an Unexpected New Target of the Anti-Hypertensive Drug Spironolactone.
Good ME, Chiu YH, Poon IKH, Medina CB, Butcher JT, Mendu SK, DeLalio LJ, Lohman AW, Leitinger N, Barrett E, Lorenz UM, Desai BN, Jaffe IZ, Bayliss DA, Isakson BE, Ravichandran KS. Good ME, et al. Among authors: poon ikh. Circ Res. 2018 Feb 16;122(4):606-615. doi: 10.1161/CIRCRESAHA.117.312380. Epub 2017 Dec 13. Circ Res. 2018. PMID: 29237722 Free PMC article.
Moving beyond size and phosphatidylserine exposure: evidence for a diversity of apoptotic cell-derived extracellular vesicles in vitro.
Poon IKH, Parkes MAF, Jiang L, Atkin-Smith GK, Tixeira R, Gregory CD, Ozkocak DC, Rutter SF, Caruso S, Santavanond JP, Paone S, Shi B, Hodge AL, Hulett MD, Chow JDY, Phan TK, Baxter AA. Poon IKH, et al. J Extracell Vesicles. 2019 Apr 26;8(1):1608786. doi: 10.1080/20013078.2019.1608786. eCollection 2019. J Extracell Vesicles. 2019. PMID: 31069027 Free PMC article.
88 results