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A non-nucleotide agonist that binds covalently to cysteine residues of STING.
Matsumoto K, Ni S, Arai H, Toyama T, Saito Y, Suzuki T, Dohmae N, Mukai K, Taguchi T. Matsumoto K, et al. Among authors: toyama t. Cell Struct Funct. 2023 Feb 16;48(1):59-70. doi: 10.1247/csf.22085. Epub 2022 Dec 28. Cell Struct Funct. 2023. PMID: 36575042 Free PMC article.
An efficient selenium transport pathway of selenoprotein P utilizing a high-affinity ApoER2 receptor variant and being independent of selenocysteine lyase.
Mizuno A, Toyama T, Ichikawa A, Sakai N, Yoshioka Y, Nishito Y, Toga R, Amesaka H, Kaneko T, Arisawa K, Tsutsumi R, Mita Y, Tanaka SI, Noguchi N, Saito Y. Mizuno A, et al. Among authors: toyama t. J Biol Chem. 2023 Aug;299(8):105009. doi: 10.1016/j.jbc.2023.105009. Epub 2023 Jul 3. J Biol Chem. 2023. PMID: 37406814 Free PMC article.
PRDX6 dictates ferroptosis sensitivity by directing cellular selenium utilization.
Ito J, Nakamura T, Toyama T, Chen D, Berndt C, Poschmann G, Mourão ASD, Doll S, Suzuki M, Zhang W, Zheng J, Trümbach D, Yamada N, Ono K, Yazaki M, Kawai Y, Arisawa M, Ohsaki Y, Shirakawa H, Wahida A, Proneth B, Saito Y, Nakagawa K, Mishima E, Conrad M. Ito J, et al. Among authors: toyama t. Mol Cell. 2024 Dec 5;84(23):4629-4644.e9. doi: 10.1016/j.molcel.2024.10.028. Epub 2024 Nov 14. Mol Cell. 2024. PMID: 39547222 Free article.
Conjugated fatty acids drive ferroptosis through chaperone-mediated autophagic degradation of GPX4 by targeting mitochondria.
Hirata Y, Yamada Y, Taguchi S, Kojima R, Masumoto H, Kimura S, Niijima T, Toyama T, Kise R, Sato E, Uchida Y, Ito J, Nakagawa K, Taguchi T, Inoue A, Saito Y, Noguchi T, Matsuzawa A. Hirata Y, et al. Among authors: toyama t. Cell Death Dis. 2024 Dec 6;15(12):884. doi: 10.1038/s41419-024-07237-w. Cell Death Dis. 2024. PMID: 39643606 Free PMC article.
977 results