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Self-Delivering RNAi Compounds for Reduction of Hyperpigmentation.
Maxwell M, Holton K, Looby RJ, Byrne M, Cardia J. Maxwell M, et al. Among authors: holton k. Clin Cosmet Investig Dermatol. 2024 Dec 27;17:3033-3044. doi: 10.2147/CCID.S498987. eCollection 2024. Clin Cosmet Investig Dermatol. 2024. PMID: 39741580 Free PMC article.
Self-delivering RNAi compounds as therapeutic agents in the central nervous system to enhance axonal regeneration after injury.
Woller SA, Ruschel J, Morquette B, Cardia J, Yan D, Holton K, Shmushkovich T, Niederst E, Bulock K, Wolfson A, Abbinanti M, Fournier AE, McKerracher L, Rosen KM. Woller SA, et al. Among authors: holton k. iScience. 2022 May 10;25(6):104379. doi: 10.1016/j.isci.2022.104379. eCollection 2022 Jun 17. iScience. 2022. PMID: 35620420 Free PMC article.
Novel hydrophobically modified asymmetric RNAi compounds (sd-rxRNA) demonstrate robust efficacy in the eye.
Byrne M, Tzekov R, Wang Y, Rodgers A, Cardia J, Ford G, Holton K, Pandarinathan L, Lapierre J, Stanney W, Bulock K, Shaw S, Libertine L, Fettes K, Khvorova A, Kaushal S, Pavco P. Byrne M, et al. Among authors: holton k. J Ocul Pharmacol Ther. 2013 Dec;29(10):855-64. doi: 10.1089/jop.2013.0148. Epub 2013 Nov 1. J Ocul Pharmacol Ther. 2013. PMID: 24180627
Biomarker discovery using machine learning in the psychosis spectrum.
Yassin W, Loedige KM, Wannan CMJ, Holton KM, Chevinsky J, Torous J, Hall MH, Ye RR, Kumar P, Chopra S, Kumar K, Khokhar JY, Margolis E, De Nadai AS. Yassin W, et al. Among authors: holton km. Biomark Neuropsychiatry. 2024 Dec;11:100107. doi: 10.1016/j.bionps.2024.100107. Epub 2024 Aug 26. Biomark Neuropsychiatry. 2024. PMID: 39687745 Free PMC article.
Organoid culture promotes dedifferentiation of mouse myoblasts into stem cells capable of complete muscle regeneration.
Price FD, Matyas MN, Gehrke AR, Chen W, Wolin EA, Holton KM, Gibbs RM, Lee A, Singu PS, Sakakeeny JS, Poteracki JM, Goune K, Pfeiffer IT, Boswell SA, Sorger PK, Srivastava M, Pfaff KL, Gussoni E, Buchanan SM, Rubin LL. Price FD, et al. Among authors: holton km. Nat Biotechnol. 2024 Sep 11. doi: 10.1038/s41587-024-02344-7. Online ahead of print. Nat Biotechnol. 2024. PMID: 39261590
118 results