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122 results

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Page 1
Co-targeting of the thymic stromal lymphopoietin receptor to decrease immunotherapeutic resistance in CRLF2-rearranged Ph-like and Down syndrome acute lymphoblastic leukemia.
Balestra T, Niswander LM, Bagashev A, Loftus JP, Ross SL, Chen RK, McClellan SM, Junco JJ, Bárcenas López DA, Rabin KR, Fry TJ, Tasian SK. Balestra T, et al. Among authors: fry tj. Leukemia. 2024 Dec 16. doi: 10.1038/s41375-024-02493-3. Online ahead of print. Leukemia. 2024. PMID: 39681640
Two decades of advances in clinical oncology - lessons learned and future directions.
Banerjee S, Booth CM, Bruera E, Büchler MW, Drilon A, Fry TJ, Ghobrial IM, Gianni L, Jain RK, Kroemer G, Llovet JM, Long GV, Pantel K, Pritchard-Jones K, Scher HI, Tabernero J, Weichselbaum RR, Weller M, Wu YL. Banerjee S, et al. Among authors: fry tj. Nat Rev Clin Oncol. 2024 Nov;21(11):771-780. doi: 10.1038/s41571-024-00945-4. Epub 2024 Oct 1. Nat Rev Clin Oncol. 2024. PMID: 39354161 No abstract available.
Targeting TGFβ-activated kinase-1 activation in microglia reduces CAR T immune effector cell-associated neurotoxicity syndrome.
Vinnakota JM, Biavasco F, Schwabenland M, Chhatbar C, Adams RC, Erny D, Duquesne S, El Khawanky N, Schmidt D, Fetsch V, Zähringer A, Salié H, Athanassopoulos D, Braun LM, Javorniczky NR, Ho JNHG, Kierdorf K, Marks R, Wäsch R, Simonetta F, Andrieux G, Pfeifer D, Monaco G, Capitini C, Fry TJ, Blank T, Blazar BR, Wagner E, Theobald M, Sommer C, Stelljes M, Reicherts C, Jeibmann A, Schittenhelm J, Monoranu CM, Rosenwald A, Kortüm M, Rasche L, Einsele H, Meyer PT, Brumberg J, Völkl S, Mackensen A, Coras R, von Bergwelt-Baildon M, Albert NL, Bartos LM, Brendel M, Holzgreve A, Mack M, Boerries M, Mackall CL, Duyster J, Henneke P, Priller J, Köhler N, Strübing F, Bengsch B, Ruella M, Subklewe M, von Baumgarten L, Gill S, Prinz M, Zeiser R. Vinnakota JM, et al. Among authors: fry tj. Nat Cancer. 2024 Aug;5(8):1227-1249. doi: 10.1038/s43018-024-00764-7. Epub 2024 May 13. Nat Cancer. 2024. PMID: 38741011
Antigen experience history directs distinct functional states of CD8+ CAR T cells during the anti-leukemia response.
DeGolier KR, Danis E, D'Antonio M, Cimons J, Yarnell M, Kedl RM, Kohler ME, Scott-Browne JP, Fry TJ. DeGolier KR, et al. Among authors: fry tj. Res Sq [Preprint]. 2023 Dec 21:rs.3.rs-3712137. doi: 10.21203/rs.3.rs-3712137/v1. Res Sq. 2023. Update in: Nat Immunol. 2025 Jan;26(1):68-81. doi: 10.1038/s41590-024-02034-1 PMID: 38196657 Free PMC article. Updated. Preprint.
Chimeric Antigen Receptor T Cells as Salvage Therapy for Post-Chimeric Antigen Receptor T Cell Failure.
Holland EM, Yates B, Steinberg SM, Yuan CM, Wang HW, Annesley C, Shalabi H, Stroncek D, Fry TJ, Krueger J, Jacoby E, Hsieh E, Bhojwani D, Gardner RA, Maude SL, Shah NN. Holland EM, et al. Among authors: fry tj. Transplant Cell Ther. 2023 Sep;29(9):574.e1-574.e10. doi: 10.1016/j.jtct.2023.06.019. Epub 2023 Jun 30. Transplant Cell Ther. 2023. PMID: 37394115 Free PMC article.
CD22 CAR T-cell associated hematologic toxicities, endothelial activation and relationship to neurotoxicity.
Jess J, Yates B, Dulau-Florea A, Parker K, Inglefield J, Lichtenstein D, Schischlik F, Ongkeko M, Wang Y, Shahani S, Cullinane A, Smith H, Kane E, Little L, Chen D, Fry TJ, Shalabi H, Wang HW, Satpathy A, Lozier J, Shah NN. Jess J, et al. Among authors: fry tj. J Immunother Cancer. 2023 Jun;11(6):e005898. doi: 10.1136/jitc-2022-005898. J Immunother Cancer. 2023. PMID: 37295816 Free PMC article.
CD4+ CAR T cells - more than helpers.
Kohler ME, Fry TJ. Kohler ME, et al. Among authors: fry tj. Nat Cancer. 2023 Jul;4(7):928-929. doi: 10.1038/s43018-023-00567-2. Nat Cancer. 2023. PMID: 37248396 No abstract available.
Hypoimmune anti-CD19 chimeric antigen receptor T cells provide lasting tumor control in fully immunocompetent allogeneic humanized mice.
Hu X, Manner K, DeJesus R, White K, Gattis C, Ngo P, Bandoro C, Tham E, Chu EY, Young C, Wells F, Basco R, Friera A, Kangeyan D, Beauchesne P, Dowdle WE, Deuse T, Fry TJ, Foster AE, Schrepfer S. Hu X, et al. Among authors: fry tj. Nat Commun. 2023 Apr 10;14(1):2020. doi: 10.1038/s41467-023-37785-2. Nat Commun. 2023. PMID: 37037829 Free PMC article.
122 results