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Cross-species comparison reveals that Hmga1 reduces H3K27me3 levels to promote cardiomyocyte proliferation and cardiac regeneration.
Bouwman M, de Bakker DEM, Honkoop H, Giovou AE, Versteeg D, Boender AR, Nguyen PD, Slotboom M, Colquhoun D, Vigil-Garcia M, Kooijman L, Janssen R, Hooijkaas IB, Günthel M, Visser KJ, Klerk M, Zentilin L, Giacca M, Kaslin J, Boink GJJ, van Rooij E, Christoffels VM, Bakkers J. Bouwman M, et al. Among authors: klerk m. Nat Cardiovasc Res. 2025 Jan;4(1):64-82. doi: 10.1038/s44161-024-00588-9. Epub 2025 Jan 2. Nat Cardiovasc Res. 2025. PMID: 39747457 Free PMC article.
Toward Biological Pacing by Cellular Delivery of Hcn2/SkM1.
Végh AMD, Verkerk AO, Cócera Ortega L, Wang J, Geerts D, Klerk M, Lodder K, Nobel R, Tijsen AJ, Devalla HD, Christoffels VM, Medina-Ramírez M, Smits AM, Tan HL, Wilders R, Goumans MJTH, Boink GJJ. Végh AMD, et al. Among authors: klerk m. Front Physiol. 2021 Jan 6;11:588679. doi: 10.3389/fphys.2020.588679. eCollection 2020. Front Physiol. 2021. PMID: 33488393 Free PMC article.
Cardiomyocyte Progenitor Cells as a Functional Gene Delivery Vehicle for Long-Term Biological Pacing.
Végh AMD, den Haan AD, Cócera Ortega L, Verkerk AO, Sluijter JPG, Bakker D, van Amersfoorth S, van Veen TAB, Klerk M, Seppen J, de Bakker JMT, Christoffels VM, Geerts D, Goumans MJTH, Tan HL, Boink GJJ. Végh AMD, et al. Among authors: klerk m. Molecules. 2019 Jan 5;24(1):181. doi: 10.3390/molecules24010181. Molecules. 2019. PMID: 30621310 Free PMC article.
Human Cardiomyocyte Progenitor Cells in Co-culture with Rat Cardiomyocytes Form a Pro-arrhythmic Substrate: Evidence for Two Different Arrhythmogenic Mechanisms.
Smit NW, Cócera Ortega L, Végh AMD, Meijborg VMF, Smits AM, Klerk M, Tijsen AJM, Tan HL, Goumans MHT, Boink GJJ, Coronel R. Smit NW, et al. Among authors: klerk m. Front Physiol. 2017 Oct 12;8:797. doi: 10.3389/fphys.2017.00797. eCollection 2017. Front Physiol. 2017. PMID: 29075204 Free PMC article.
Targeting the Microtubule EB1-CLASP2 Complex Modulates NaV1.5 at Intercalated Discs.
Marchal GA, Jouni M, Chiang DY, Pérez-Hernández M, Podliesna S, Yu N, Casini S, Potet F, Veerman CC, Klerk M, Lodder EM, Mengarelli I, Guan K, Vanoye CG, Rothenberg E, Charpentier F, Redon R, George AL Jr, Verkerk AO, Bezzina CR, MacRae CA, Burridge PW, Delmar M, Galjart N, Portero V, Remme CA. Marchal GA, et al. Among authors: klerk m. Circ Res. 2021 Jul 23;129(3):349-365. doi: 10.1161/CIRCRESAHA.120.318643. Epub 2021 Jun 7. Circ Res. 2021. PMID: 34092082 Free PMC article.
91 results