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114 results

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Adipose tissue eQTL meta-analysis highlights the contribution of allelic heterogeneity to gene expression regulation and cardiometabolic traits.
Brotman SM, El-Sayed Moustafa JS, Guan L, Broadaway KA, Wang D, Jackson AU, Welch R, Currin KW, Tomlinson M, Vadlamudi S, Stringham HM, Roberts AL, Lakka TA, Oravilahti A, Fernandes Silva L, Narisu N, Erdos MR, Yan T, Bonnycastle LL, Raulerson CK, Raza Y, Yan X, Parker SCJ, Kuusisto J, Pajukanta P, Tuomilehto J, Collins FS, Boehnke M, Love MI, Koistinen HA, Laakso M, Mohlke KL, Small KS, Scott LJ. Brotman SM, et al. Among authors: love mi. Nat Genet. 2025 Jan;57(1):180-192. doi: 10.1038/s41588-024-01982-6. Epub 2025 Jan 2. Nat Genet. 2025. PMID: 39747594
Adipose Tissue Gene Expression Associations Reveal Hundreds of Candidate Genes for Cardiometabolic Traits.
Raulerson CK, Ko A, Kidd JC, Currin KW, Brotman SM, Cannon ME, Wu Y, Spracklen CN, Jackson AU, Stringham HM, Welch RP, Fuchsberger C, Locke AE, Narisu N, Lusis AJ, Civelek M, Furey TS, Kuusisto J, Collins FS, Boehnke M, Scott LJ, Lin DY, Love MI, Laakso M, Pajukanta P, Mohlke KL. Raulerson CK, et al. Among authors: love mi. Am J Hum Genet. 2019 Oct 3;105(4):773-787. doi: 10.1016/j.ajhg.2019.09.001. Epub 2019 Sep 26. Am J Hum Genet. 2019. PMID: 31564431 Free PMC article.
Assessing exposure effects on gene expression.
Reifeis SA, Hudgens MG, Civelek M, Mohlke KL, Love MI. Reifeis SA, et al. Among authors: love mi. Genet Epidemiol. 2020 Sep;44(6):601-610. doi: 10.1002/gepi.22324. Epub 2020 Jun 8. Genet Epidemiol. 2020. PMID: 32511796 Free PMC article.
Brain-trait-associated variants impact cell-type-specific gene regulation during neurogenesis.
Aygün N, Elwell AL, Liang D, Lafferty MJ, Cheek KE, Courtney KP, Mory J, Hadden-Ford E, Krupa O, de la Torre-Ubieta L, Geschwind DH, Love MI, Stein JL. Aygün N, et al. Among authors: love mi. Am J Hum Genet. 2021 Sep 2;108(9):1647-1668. doi: 10.1016/j.ajhg.2021.07.011. Epub 2021 Aug 19. Am J Hum Genet. 2021. PMID: 34416157 Free PMC article.
Wnt activity reveals context-specific genetic effects on gene regulation in neural progenitors.
Matoba N, Le BD, Valone JM, Wolter JM, Mory J, Liang D, Aygün N, Broadaway KA, Bond ML, Mohlke KL, Zylka MJ, Love MI, Stein JL. Matoba N, et al. Among authors: love mi. bioRxiv [Preprint]. 2023 Apr 19:2023.02.07.527357. doi: 10.1101/2023.02.07.527357. bioRxiv. 2023. Update in: Nat Neurosci. 2024 Dec;27(12):2430-2442. doi: 10.1038/s41593-024-01773-6 PMID: 36798360 Free PMC article. Updated. Preprint.
Cell-Type Composition Affects Adipose Gene Expression Associations With Cardiometabolic Traits.
Brotman SM, Oravilahti A, Rosen JD, Alvarez M, Heinonen S, van der Kolk BW, Fernandes Silva L, Perrin HJ, Vadlamudi S, Pylant C, Deochand S, Basta PV, Valone JM, Narain MN, Stringham HM, Boehnke M, Kuusisto J, Love MI, Pietiläinen KH, Pajukanta P, Laakso M, Mohlke KL. Brotman SM, et al. Among authors: love mi. Diabetes. 2023 Nov 1;72(11):1707-1718. doi: 10.2337/db23-0365. Diabetes. 2023. PMID: 37647564 Free PMC article.
Adipose tissue eQTL meta-analysis reveals the contribution of allelic heterogeneity to gene expression regulation and cardiometabolic traits.
Brotman SM, El-Sayed Moustafa JS, Guan L, Broadaway KA, Wang D, Jackson AU, Welch R, Currin KW, Tomlinson M, Vadlamudi S, Stringham HM, Roberts AL, Lakka TA, Oravilahti A, Silva LF, Narisu N, Erdos MR, Yan T, Bonnycastle LL, Raulerson CK, Raza Y, Yan X, Parker SCJ, Kuusisto J, Pajukanta P, Tuomilehto J, Collins FS, Boehnke M, Love MI, Koistinen HA, Laakso M, Mohlke KL, Small KS, Scott LJ. Brotman SM, et al. Among authors: love mi. bioRxiv [Preprint]. 2023 Oct 27:2023.10.26.563798. doi: 10.1101/2023.10.26.563798. bioRxiv. 2023. Update in: Nat Genet. 2025 Jan;57(1):180-192. doi: 10.1038/s41588-024-01982-6 PMID: 37961277 Free PMC article. Updated. Preprint.
Response eQTLs, chromatin accessibility, and 3D chromatin structure in chondrocytes provide mechanistic insight into osteoarthritis risk.
Kramer NE, Byun S, Coryell P, D'Costa S, Thulson E, Kim H, Parkus SM, Bond ML, Klein ER, Shine J, Chubinskaya S, Love MI, Mohlke KL, Diekman BO, Loeser RF, Phanstiel DH. Kramer NE, et al. Among authors: love mi. bioRxiv [Preprint]. 2024 Oct 31:2024.05.05.592567. doi: 10.1101/2024.05.05.592567. bioRxiv. 2024. Update in: Cell Genom. 2025 Jan 8;5(1):100738. doi: 10.1016/j.xgen.2024.100738 PMID: 38952796 Free PMC article. Updated. Preprint.
114 results