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Page 1
Examination of MGMT as a risk gene for dementia in the Amish.
Main LR, Song YE, Lynn A, Laux RA, Miskimen KL, Osterman MD, Cuccaro ML, Ogrocki PK, Lerner AJ, Vance JM, Fuzzell MD, Fuzzell SL, Hochstetler SD, Dorfsman DA, Caywood LJ, Prough MB, Adams LD, Clouse JE, Herington SD, Scott WK, Pericak-Vance MA, Haines JL. Main LR, et al. Among authors: dorfsman da. Alzheimers Dement. 2024 Dec 23. doi: 10.1002/alz.14356. Online ahead of print. Alzheimers Dement. 2024. PMID: 39711484
Genetic analysis of cognitive preservation in the midwestern Amish reveals a novel locus on chromosome 2.
Main LR, Song YE, Lynn A, Laux RA, Miskimen KL, Osterman MD, Cuccaro ML, Ogrocki PK, Lerner AJ, Vance JM, Fuzzell D, Fuzzell SL, Hochstetler SD, Dorfsman DA, Caywood LJ, Prough MB, Adams LD, Clouse JE, Herington SD, Scott WK, Pericak-Vance MA, Haines JL. Main LR, et al. Among authors: dorfsman da. Alzheimers Dement. 2024 Nov;20(11):7453-7464. doi: 10.1002/alz.14045. Epub 2024 Oct 8. Alzheimers Dement. 2024. PMID: 39376159 Free PMC article.
Corpora amylacea negatively correlate with hippocampal tau pathology in Alzheimer's disease.
Dallmeier JD, Gober R, Vontell RT, Barreda A, Dorfsman DA, Davis DA, Sun X, Brzostowicki D, Bennett I, Garamszegi SP, Wander CM, Cohen T, Scott WK. Dallmeier JD, et al. Among authors: dorfsman da. Front Neurosci. 2024 Feb 29;18:1286924. doi: 10.3389/fnins.2024.1286924. eCollection 2024. Front Neurosci. 2024. PMID: 38486969 Free PMC article.
Genetic analysis of cognitive preservation in the midwestern Amish reveals a novel locus on chromosome 2.
Main LR, Song YE, Lynn A, Laux RA, Miskimen KL, Osterman MD, Cuccaro ML, Ogrocki PK, Lerner AJ, Vance JM, Fuzzell MD, Fuzzell SL, Hochstetler SD, Dorfsman DA, Caywood LJ, Prough MB, Adams LD, Clouse JE, Herington SD, Scott WK, Pericak-Vance MA, Haines JL. Main LR, et al. Among authors: dorfsman da. medRxiv [Preprint]. 2023 Dec 14:2023.12.13.23299932. doi: 10.1101/2023.12.13.23299932. medRxiv. 2023. Update in: Alzheimers Dement. 2024 Nov;20(11):7453-7464. doi: 10.1002/alz.14045 PMID: 38168325 Free PMC article. Updated. Preprint.
Founder population-specific weights yield improvements in performance of polygenic risk scores for Alzheimer disease in the Midwestern Amish.
Osterman MD, Song YE, Lynn A, Miskimen K, Adams LD, Laux RA, Caywood LJ, Prough MB, Clouse JE, Herington SD, Slifer SH, Fuzzell SL, Hochstetler SD, Main LR, Dorfsman DA, Zaman AF, Ogrocki P, Lerner AJ, Vance JM, Cuccaro ML, Scott WK, Pericak-Vance MA, Haines JL. Osterman MD, et al. Among authors: dorfsman da. HGG Adv. 2023 Oct 12;4(4):100241. doi: 10.1016/j.xhgg.2023.100241. Epub 2023 Sep 22. HGG Adv. 2023. PMID: 37742071 Free PMC article.
Visuospatial and Verbal Memory Differences in Amish Individuals With Alzheimer Disease and Related Dementias.
Prough MB, Zaman A, Caywood LJ, Clouse JE, Herington SD, Slifer SH, Dorfsman DA, Adams LA, Laux RA, Song YE, Lynn A, Fuzzell D, Fuzzell SL, Miller SD, Miskimen K, Main LR, Osterman MD, Ogrocki P, Lerner AJ, Vance JM, Haines JL, Scott WK, Pericak-Vance M, Cuccaro ML. Prough MB, et al. Among authors: dorfsman da. Alzheimer Dis Assoc Disord. 2023 Jul-Sep 01;37(3):195-199. doi: 10.1097/WAD.0000000000000570. Epub 2023 Aug 2. Alzheimer Dis Assoc Disord. 2023. PMID: 37561946 Free PMC article.
The genetic architecture of Alzheimer disease risk in the Ohio and Indiana Amish.
Osterman MD, Song YE, Adams LD, Laux RA, Caywood LJ, Prough MB, Clouse JE, Herington SD, Slifer SH, Lynn A, Fuzzell MD, Fuzzell SL, Hochstetler SD, Miskimen K, Main LR, Dorfsman DA, Ogrocki P, Lerner AJ, Ramos J, Vance JM, Cuccaro ML, Scott WK, Pericak-Vance MA, Haines JL. Osterman MD, et al. Among authors: dorfsman da. HGG Adv. 2022 Apr 27;3(3):100114. doi: 10.1016/j.xhgg.2022.100114. eCollection 2022 Jul 14. HGG Adv. 2022. PMID: 35599847 Free PMC article.
Adaptive introgression of the beta-globin cluster in two Andean waterfowl.
Graham AM, Peters JL, Wilson RE, Muñoz-Fuentes V, Green AJ, Dorfsman DA, Valqui TH, Winker K, McCracken KG. Graham AM, et al. Among authors: dorfsman da. Heredity (Edinb). 2021 Jul;127(1):107-123. doi: 10.1038/s41437-021-00437-6. Epub 2021 Apr 26. Heredity (Edinb). 2021. PMID: 33903741 Free PMC article.
Increased APOE ε4 expression is associated with the difference in Alzheimer's disease risk from diverse ancestral backgrounds.
Griswold AJ, Celis K, Bussies PL, Rajabli F, Whitehead PL, Hamilton-Nelson KL, Beecham GW, Dykxhoorn DM, Nuytemans K, Wang L, Gardner OK, Dorfsman DA, Bigio EH, Mesulam MM, Weintraub S, Geula C, Gearing M, McGrath-Martinez E, Dalgard CL, Scott WK, Haines JL, Pericak-Vance MA, Young JI, Vance JM. Griswold AJ, et al. Among authors: dorfsman da. Alzheimers Dement. 2021 Jul;17(7):1179-1188. doi: 10.1002/alz.12287. Epub 2021 Feb 1. Alzheimers Dement. 2021. PMID: 33522086 Free PMC article.
Use of local genetic ancestry to assess TOMM40-523' and risk for Alzheimer disease.
Bussies PL, Rajabli F, Griswold A, Dorfsman DA, Whitehead P, Adams LD, Mena PR, Cuccaro M, Haines JL, Byrd GS, Beecham GW, Pericak-Vance MA, Young JI, Vance JM. Bussies PL, et al. Among authors: dorfsman da. Neurol Genet. 2020 Mar 3;6(2):e404. doi: 10.1212/NXG.0000000000000404. eCollection 2020 Apr. Neurol Genet. 2020. PMID: 32337333 Free PMC article.