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Page 1
Refining breast cancer genetic risk and biology through multi-ancestry fine-mapping analyses of 192 risk regions.
Jia G, Chen Z, Ping J, Cai Q, Tao R, Li C, Bauer JA, Xie Y, Ambs S, Barnard ME, Chen Y, Choi JY, Gao YT, Garcia-Closas M, Gu J, Hu JJ, Iwasaki M, John EM, Kweon SS, Li CI, Matsuda K, Matsuo K, Nathanson KL, Nemesure B, Olopade OI, Pal T, Park SK, Park B, Press MF, Sanderson M, Sandler DP, Shen CY, Troester MA, Yao S, Zheng Y, Ahearn T, Brewster AM, Falusi A, Hennis AJM, Ito H, Kubo M, Lee ES, Makumbi T, Ndom P, Noh DY, O'Brien KM, Ojengbede O, Olshan AF, Park MH, Reid S, Yamaji T, Zirpoli G, Butler EN, Huang M, Low SK, Obafunwa J, Weinberg CR, Zhang H, Zhao H, Cote ML, Ambrosone CB, Huo D, Li B, Kang D, Palmer JR, Shu XO, Haiman CA, Guo X, Long J, Zheng W. Jia G, et al. Among authors: ambs s. Nat Genet. 2025 Jan 3. doi: 10.1038/s41588-024-02031-y. Online ahead of print. Nat Genet. 2025. PMID: 39753771
Tumor NOS2 and COX2 Spatial Juxtaposition with CD8+ T Cells Promote Metastatic and Cancer Stem Cell Niches that Lead to Poor Outcome in ER- Breast Cancer.
Ridnour LA, Heinz WF, Cheng RYS, Wink AL, Kedei N, Pore M, Imtiaz F, Femino EL, Gonzalez AL, Coutinho LL, Moffat RL, Butcher D, Edmondson EF, Li X, Rangel MC, Kinders RJ, Rittscher J, Lipkowitz S, Wong STC, Anderson SK, McVicar DW, Glynn SA, Billiar TR, Chang JC, Hewitt SM, Ambs S, Lockett SJ, Wink DA. Ridnour LA, et al. Among authors: ambs s. Cancer Res Commun. 2024 Oct 1;4(10):2766-2782. doi: 10.1158/2767-9764.CRC-24-0235. Cancer Res Commun. 2024. PMID: 39356141 Free PMC article.
West African Genetic Ancestry, Neighborhood Deprivation, and Prostate Cancer.
Pichardo CM, Ezeani A, Acevedo AM, Agurs-Collins T, Bailey-Whyte M, Dorsey TH, Harris AR, Franklin J, Kittles RA, Lawrence WR, Loffredo CA, Minas TZ, Pichardo MS, Ryan BM, Tang W, Wooten W, Liu J, Ambs S. Pichardo CM, et al. Among authors: ambs s. JAMA Netw Open. 2024 Sep 3;7(9):e2433546. doi: 10.1001/jamanetworkopen.2024.33546. JAMA Netw Open. 2024. PMID: 39283637 Free PMC article.
Adjuvant COX inhibition augments STING signaling and cytolytic T cell infiltration in irradiated 4T1 tumors.
Ridnour LA, Cheng RY, Kedei N, Somasundaram V, Bhattacharyya DD, Basudhar D, Wink AL, Walke AJ, Kim C, Heinz WF, Edmondson EF, Butcher DO, Warner AC, Dorsey TH, Pore M, Kinders RJ, Lipkowitz S, Bryant RJ, Rittscher J, Wong ST, Hewitt SM, Chang JC, Shalaby A, Callagy GM, Glynn SA, Ambs S, Anderson SK, McVicar DW, Lockett SJ, Wink DA. Ridnour LA, et al. Among authors: ambs s. JCI Insight. 2024 May 21;9(12):e165356. doi: 10.1172/jci.insight.165356. JCI Insight. 2024. PMID: 38912586 Free PMC article.
Case-Case Genome-Wide Analyses Identify Subtype-Informative Variants That Confer Risk for Breast Cancer.
Sun X, Verma SP, Jia G, Wang X, Ping J, Guo X, Shu XO, Chen J, Derkach A, Cai Q, Liang X, Long J, Offit K, Oh JH, Reiner AS, Watt GP, Woods M, Yang Y, Ambrosone CB, Ambs S, Chen Y, Concannon P, Garcia-Closas M, Gu J, Haiman CA, Hu JJ, Huo D, John EM, Knight JA, Li CI, Lynch CF, Mellemkjær L, Nathanson KL, Nemesure B, Olopade OI, Olshan AF, Pal T, Palmer JR, Press MF, Sanderson M, Sandler DP, Troester MA, Zheng W, Bernstein JL, Buas MF, Shu X. Sun X, et al. Among authors: ambs s. Cancer Res. 2024 Aug 1;84(15):2533-2548. doi: 10.1158/0008-5472.CAN-23-3854. Cancer Res. 2024. PMID: 38832928
Genome-wide association analyses of breast cancer in women of African ancestry identify new susceptibility loci and improve risk prediction.
Jia G, Ping J, Guo X, Yang Y, Tao R, Li B, Ambs S, Barnard ME, Chen Y, Garcia-Closas M, Gu J, Hu JJ, Huo D, John EM, Li CI, Li JL, Nathanson KL, Nemesure B, Olopade OI, Pal T, Press MF, Sanderson M, Sandler DP, Shu XO, Troester MA, Yao S, Adejumo PO, Ahearn T, Brewster AM, Hennis AJM, Makumbi T, Ndom P, O'Brien KM, Olshan AF, Oluwasanu MM, Reid S, Butler EN, Huang M, Ntekim A, Qian H, Zhang H, Ambrosone CB, Cai Q, Long J, Palmer JR, Haiman CA, Zheng W. Jia G, et al. Among authors: ambs s. Nat Genet. 2024 May;56(5):819-826. doi: 10.1038/s41588-024-01736-4. Epub 2024 May 13. Nat Genet. 2024. PMID: 38741014
Using genome and transcriptome data from African-ancestry female participants to identify putative breast cancer susceptibility genes.
Ping J, Jia G, Cai Q, Guo X, Tao R, Ambrosone C, Huo D, Ambs S, Barnard ME, Chen Y, Garcia-Closas M, Gu J, Hu JJ, John EM, Li CI, Nathanson K, Nemesure B, Olopade OI, Pal T, Press MF, Sanderson M, Sandler DP, Yoshimatsu T, Adejumo PO, Ahearn T, Brewster AM, Hennis AJM, Makumbi T, Ndom P, O'Brien KM, Olshan AF, Oluwasanu MM, Reid S, Yao S, Butler EN, Huang M, Ntekim A, Li B, Troester MA, Palmer JR, Haiman CA, Long J, Zheng W. Ping J, et al. Among authors: ambs s. Nat Commun. 2024 May 2;15(1):3718. doi: 10.1038/s41467-024-47650-5. Nat Commun. 2024. PMID: 38697998 Free PMC article.
188 results