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MYB represses ζ-globin expression through upregulating ETO2.
Dong Z, Ye Y, Zhang W, Luo H, Li J, Zhang Q, Zhang X, Guo X, Xu X. Dong Z, et al. Among authors: zhang q, zhang w, zhang x. Acta Biochim Biophys Sin (Shanghai). 2025 Jan 6. doi: 10.3724/abbs.2024239. Online ahead of print. Acta Biochim Biophys Sin (Shanghai). 2025. PMID: 39757769 Free article.
Epigenetic inactivation of ERF reactivates γ-globin expression in β-thalassemia.
Bao X, Zhang X, Wang L, Wang Z, Huang J, Zhang Q, Ye Y, Liu Y, Chen D, Zuo Y, Liu Q, Xu P, Huang B, Fang J, Lao J, Feng X, Li Y, Kurita R, Nakamura Y, Yu W, Ju C, Huang C, Mohandas N, Li D, Zhao C, Xu X. Bao X, et al. Among authors: zhang q, zhang x. Am J Hum Genet. 2021 Apr 1;108(4):709-721. doi: 10.1016/j.ajhg.2021.03.005. Epub 2021 Mar 17. Am J Hum Genet. 2021. PMID: 33735615 Free PMC article.
Quantification of human embryonic ζ-globin chains in Southeast Asian deletion (--SEA) carriers.
Ye Y, Sun G, Ren Z, Liang Y, Luo H, Lin P, Wang X, Dong Z, Huang L, Qin L, Yu W, Wang G, Zhou Y, Tang J, Lou J, Liu Y, Zeng X, Chen Y, Li Y, Zhang Q, Huang J, Zhu P, Lin L, Zhang X, Xu X. Ye Y, et al. Among authors: zhang q, zhang x. J Clin Pathol. 2023 Nov;76(11):784-789. doi: 10.1136/jcp-2022-208159. Epub 2022 Aug 25. J Clin Pathol. 2023. PMID: 36008105
GATA zinc finger domain-containing protein 2A (GATAD2A) deficiency reactivates fetal haemoglobin in patients with β-thalassaemia through impaired formation of methyl-binding domain protein 2 (MBD2)-containing nucleosome remodelling and deacetylation (NuRD) complex.
Liang Y, Zhang X, Liu Y, Wang L, Ye Y, Tan X, Pu J, Zhang Q, Bao X, Wei X, Li D, Kurita R, Nakamura Y, Li D, Xu X. Liang Y, et al. Among authors: zhang q, zhang x. Br J Haematol. 2021 Jun;193(6):1220-1227. doi: 10.1111/bjh.17511. Epub 2021 May 17. Br J Haematol. 2021. PMID: 33997955
Whole-genome Sequencing Association Analysis of Quantitative Platelet Traits in A Large Cohort of β-thalassemia.
Wang X, Zhang Q, Chen X, Huang Y, Zhang W, Liao L, Zhang X, Huang B, Huang Y, Ye Y, Song M, Lao J, Chen J, Feng X, Long X, Liu Z, Zhu W, Yu L, Fan C, Tang D, Zhong T, Fang M, Li C, Niu C, Huang L, Lin B, Hua X, Jin X, Li Z, Xu X. Wang X, et al. Among authors: zhang q, zhang w, zhang x. Genomics Proteomics Bioinformatics. 2024 Sep 27:qzae065. doi: 10.1093/gpbjnl/qzae065. Online ahead of print. Genomics Proteomics Bioinformatics. 2024. PMID: 39331630 Free article.
Mutations in AMBRA1 aggravate β-thalassemia by impairing autophagy-mediated clearance of free α-globin.
Long Y, Zhang Q, Ling L, Zhuang Y, Wei X, Huang H, Lu Z, Huang Y, Chen X, Ye Y, Feng X, Zhang HH, Huang B, Huang Y, Liang Y, Fang M, Nakamura Y, Lin B, Zhang X, Lu D, Jin X, Xu X. Long Y, et al. Among authors: zhang q, zhang hh, zhang x. Blood. 2024 Dec 18:blood.2023022688. doi: 10.1182/blood.2023022688. Online ahead of print. Blood. 2024. PMID: 39693613
Haplotype-Resolved Genotyping and Association Analysis of 1,020 β-Thalassemia Patients by Targeted Long-Read Sequencing.
Ye Y, Niu C, Mao A, Qin L, Zhan J, Chen W, Liu Z, Xie T, Zhang Q, Li J, Huang L, Meng W, Liu Y, Liao L, Cai J, Liu R, Zhang X, Zeng L, Li Y, Lin B, Li K, Hua X, Huang B, Qin H, Huang Y, Huang Z, Lao J, Qu X, Chen J, Feng X, Liu Q, Lin W, Zhou X, Liang Y, Long X, Qin J, Yan L, Zhu W, Yu L, Fan C, Tang D, Zhong T, Tan J, Ren Z, Xu X. Ye Y, et al. Among authors: zhang q, zhang x. Adv Sci (Weinh). 2024 Dec 31:e2410992. doi: 10.1002/advs.202410992. Online ahead of print. Adv Sci (Weinh). 2024. PMID: 39737841
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