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709 results

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Page 1
Gene signatures derived from transcriptomic-causal networks stratify colorectal cancer patients for effective targeted therapy.
Yazdani A, Lenz HJ, Pillonetto G, Mendez-Giraldez R, Yazdani A, Sanoff H, Hadi R, Samiei E, Venook AP, Ratain MJ, Rashid N, Vincent BG, Qu X, Wen Y, Kosorok M, Symmans WF, Shen JPYC, Lee MS, Kopetz S, Nixon AB, Bertagnolli MM, Perou CM, Innocenti F. Yazdani A, et al. Among authors: lenz hj. Commun Med (Lond). 2025 Jan 8;5(1):9. doi: 10.1038/s43856-024-00728-z. Commun Med (Lond). 2025. PMID: 39779996 Free PMC article.
Combining antivascular endothelial growth factor and anti-epidermal growth factor receptor antibodies: randomized phase II study of irinotecan and cetuximab with/without ramucirumab in second-line colorectal cancer (ECOG-ACRIN E7208).
Hochster HS, Catalano P, Weitz M, Mitchell EP, Cohen D, O'Dwyer PJ, Faller BA, Kortmansky JS, O'Hara MH, Kricher SM, Lacy J, Lenz HJ, Verma U, Benson AB. Hochster HS, et al. Among authors: lenz hj. J Natl Cancer Inst. 2024 Sep 1;116(9):1487-1494. doi: 10.1093/jnci/djae114. J Natl Cancer Inst. 2024. PMID: 38775718 Clinical Trial.
Nivolumab plus Ipilimumab in Microsatellite-Instability-High Metastatic Colorectal Cancer.
Andre T, Elez E, Van Cutsem E, Jensen LH, Bennouna J, Mendez G, Schenker M, de la Fouchardiere C, Limon ML, Yoshino T, Li J, Lenz HJ, Manzano Mozo JL, Tortora G, Garcia-Carbonero R, Dahan L, Chalabi M, Joshi R, Goekkurt E, Braghiroli MI, Cil T, Cela E, Chen T, Lei M, Dixon M, Abdullaev S, Lonardi S; CheckMate 8HW Investigators. Andre T, et al. Among authors: lenz hj. N Engl J Med. 2024 Nov 28;391(21):2014-2026. doi: 10.1056/NEJMoa2402141. N Engl J Med. 2024. PMID: 39602630 Clinical Trial.
Phase I-II study of OBI-888, a humanized monoclonal IgG1 antibody against the tumor-associated carbohydrate antigen Globo H, in patients with advanced solid tumors.
Tsimberidou AM, Grothey A, Sigal D, Lenz HJ, Hochster HS, Chao Y, Bai LY, Yen CL, Xu D, Saville MW. Tsimberidou AM, et al. Among authors: lenz hj. Cancer Chemother Pharmacol. 2024 Dec;94(6):787-798. doi: 10.1007/s00280-024-04714-z. Epub 2024 Sep 23. Cancer Chemother Pharmacol. 2024. PMID: 39311947 Free PMC article. Clinical Trial.
Comprehensive characterization of MCL-1 in patients with colorectal cancer: Expression, molecular profiles, and outcomes.
Mittal P, Battaglin F, Baca Y, Xiu J, Farrell A, Soni S, Lo JH, Torres-Gonzalez L, Algaze S, Jayachandran P, Ashouri K, Wong A, Zhang W, Yu J, Zhang L, Weinberg BA, Lou E, Shields AF, Goldberg RM, Marshall JL, Goel S, Singh IK, Lenz HJ. Mittal P, et al. Among authors: lenz hj. Int J Cancer. 2024 Dec 30. doi: 10.1002/ijc.35304. Online ahead of print. Int J Cancer. 2024. PMID: 39740007
Evidence for a causal link between intra-pancreatic fat deposition and pancreatic cancer: A prospective cohort and Mendelian randomization study.
Yamazaki H, Streicher SA, Wu L, Fukuhara S, Wagner R, Heni M, Grossman SR, Lenz HJ, Setiawan VW, Le Marchand L, Huang BZ. Yamazaki H, et al. Among authors: lenz hj. Cell Rep Med. 2024 Dec 17;5(12):101842. doi: 10.1016/j.xcrm.2024.101842. Epub 2024 Dec 3. Cell Rep Med. 2024. PMID: 39631403 Free PMC article. No abstract available.
709 results