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Page 1
Developing Topics.
Stokkel ME, Vermunt L, Knol J, Piersma S, Pham TV, Gagestein B, de Haas RRG, Lemstra AW, Pijnenburg YAL, Visser PJ, Tijms BM, Teunissen C, Jimenez CR. Stokkel ME, et al. Among authors: gagestein b. Alzheimers Dement. 2024 Dec;20 Suppl 8:e095441. doi: 10.1002/alz.095441. Alzheimers Dement. 2024. PMID: 39783320
Discovery of isoquinoline sulfonamides as allosteric gyrase inhibitors with activity against fluoroquinolone-resistant bacteria.
Bakker AT, Kotsogianni I, Avalos M, Punt JM, Liu B, Piermarini D, Gagestein B, Slingerland CJ, Zhang L, Willemse JJ, Ghimire LB, van den Berg RJHBN, Janssen APA, Ottenhoff THM, van Boeckel CAA, van Wezel GP, Ghilarov D, Martin NI, van der Stelt M. Bakker AT, et al. Among authors: gagestein b. Nat Chem. 2024 Sep;16(9):1462-1472. doi: 10.1038/s41557-024-01516-x. Epub 2024 Jun 19. Nat Chem. 2024. PMID: 38898213 Free PMC article.
Comparative Photoaffinity Profiling of Omega-3 Signaling Lipid Probes Reveals Prostaglandin Reductase 1 as a Metabolic Hub in Human Macrophages.
Gagestein B, von Hegedus JH, Kwekkeboom JC, Heijink M, Blomberg N, van der Wel T, Florea BI, van den Elst H, Wals K, Overkleeft HS, Giera M, Toes REM, Ioan-Facsinay A, van der Stelt M. Gagestein B, et al. J Am Chem Soc. 2022 Oct 19;144(41):18938-18947. doi: 10.1021/jacs.2c06827. Epub 2022 Oct 5. J Am Chem Soc. 2022. PMID: 36197299 Free PMC article.
Live-Cell Imaging of Sterculic Acid-a Naturally Occurring 1,2-Cyclopropene Fatty Acid-by Bioorthogonal Reaction with Turn-On Tetrazine-Fluorophore Conjugates.
Bertheussen K, van de Plassche M, Bakkum T, Gagestein B, Ttofi I, Sarris AJC, Overkleeft HS, van der Stelt M, van Kasteren SI. Bertheussen K, et al. Among authors: gagestein b. Angew Chem Int Ed Engl. 2022 Sep 19;61(38):e202207640. doi: 10.1002/anie.202207640. Epub 2022 Aug 8. Angew Chem Int Ed Engl. 2022. PMID: 35838324 Free PMC article.
Olaparib-Based Photoaffinity Probes for PARP-1 Detection in Living Cells.
Voorneveld J, Florea BI, Bakkum T, Mendowicz RJ, van der Veer MS, Gagestein B, van Kasteren SI, van der Stelt M, Overkleeft HS, Filippov DV. Voorneveld J, et al. Among authors: gagestein b. Chembiochem. 2020 Sep 1;21(17):2431-2434. doi: 10.1002/cbic.202000042. Epub 2020 May 13. Chembiochem. 2020. PMID: 32282108 Free PMC article.
Comprehensive structure-activity-relationship of azaindoles as highly potent FLT3 inhibitors.
Grimm SH, Gagestein B, Keijzer JF, Liu N, Wijdeven RH, Lenselink EB, Tuin AW, van den Nieuwendijk AMCH, van Westen GJP, van Boeckel CAA, Overkleeft HS, Neefjes J, van der Stelt M. Grimm SH, et al. Among authors: gagestein b. Bioorg Med Chem. 2019 Mar 1;27(5):692-699. doi: 10.1016/j.bmc.2019.01.006. Epub 2019 Jan 14. Bioorg Med Chem. 2019. PMID: 30661740 Free article.
Opportunities for Lipid-Based Probes in the Field of Immunology.
Koenders STA, Gagestein B, van der Stelt M. Koenders STA, et al. Among authors: gagestein b. Curr Top Microbiol Immunol. 2019;420:283-319. doi: 10.1007/82_2018_127. Curr Top Microbiol Immunol. 2019. PMID: 30242513 Review.