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154 results

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Page 1
Evaluating the association of APOE genotype and cognitive resilience in SuperAgers.
Durant A, Mukherjee S, Lee ML, Choi SE, Scollard P, Klinedinst BS, Trittschuh EH, Mez J, Farrer LA, Gifford KA, Cruchaga C, Hassenstab J, Naj AC, Wang LS, Johnson SC, Engelman CD, Kukull WA, Keene CD, Saykin AJ, Cuccaro ML, Kunkle BW, Pericak-Vance MA, Martin ER, Bennett DA, Barnes LL, Schneider JA, Bush WS, Haines JL, Mayeux R, Vardarajan BN, Albert MS, Thompson PM, Jefferson AL; Alzheimer’s Disease Neuroimaging Initiative (ADNI); Alzheimer’s Disease Genetics Consortium (ADGC); Alzheimer’s Disease Sequencing Project (ADSP); Crane PK, Dumitrescu L, Archer DB, Hohman TJ, Gaynor LS. Durant A, et al. Among authors: cuccaro ml. medRxiv [Preprint]. 2025 Jan 7:2025.01.07.25320117. doi: 10.1101/2025.01.07.25320117. medRxiv. 2025. PMID: 39830268 Free PMC article. Preprint.
Deleterious coding variation associated with autism is consistent across populations, as exemplified by admixed Latin American populations.
Avila MN, Jung S, Satterstrom FK, Fu JM, Levy T, Sloofman LG, Klei L, Pichardo T, Stevens CR, Cusick CM, Ames JL, Campos GS, Cerros H, Chaskel R, Costa CIS, Cuccaro ML, Lopez ADP, Fernandez M, Ferro E, Galeano L, Girardi ACDES, Griswold AJ, Hernandez LC, Lourenço N, Ludena Y, Nuñez DL, Oyama R, Peña KP, Pessah I, Schmidt R, Sweeney HM, Tolentino L, Wang JYT, Albores-Gallo L, Croen LA, Cruz-Fuentes CS, Hertz-Picciotto I, Kolevzon A, Lattig MC, Mayo L, Passos-Bueno MR, Pericak-Vance MA, Siper PM, Tassone F, Trelles MP; Autism Sequencing Consortium; Talkowski ME, Daly MJ, Mahjani B, De Rubeis S, Cook EH, Roeder K, Betancur C, Devlin B, Buxbaum JD. Avila MN, et al. Among authors: cuccaro ml. medRxiv [Preprint]. 2025 Jan 6:2024.12.27.24319460. doi: 10.1101/2024.12.27.24319460. medRxiv. 2025. PMID: 39830258 Free PMC article. Preprint.
Alzheimer Disease Plasma Biomarkers in the Mid-Western Amish.
Wang P, Song YE, Lynn A, Miskimen K, Gulyayev A, Prough MB, Dorfsman DA, Laux RA, Fuzzell SL, Hochstetler SD, Zaman AF, Adams LD, Caywood LJ, Clouse JE, Herington SD, Whitehead P, Liu Y, Moore N, Ogrocki P, Lerner AJ, Griswold AJ, Vance JM, Cuccaro ML, Scott WK, Pericak-Vance MA, Haines JL. Wang P, et al. Among authors: cuccaro ml. medRxiv [Preprint]. 2025 Jan 3:2024.12.23.24319579. doi: 10.1101/2024.12.23.24319579. medRxiv. 2025. PMID: 39802805 Free PMC article. Preprint.
Examination of MGMT as a risk gene for dementia in the Amish.
Main LR, Song YE, Lynn A, Laux RA, Miskimen KL, Osterman MD, Cuccaro ML, Ogrocki PK, Lerner AJ, Vance JM, Fuzzell MD, Fuzzell SL, Hochstetler SD, Dorfsman DA, Caywood LJ, Prough MB, Adams LD, Clouse JE, Herington SD, Scott WK, Pericak-Vance MA, Haines JL. Main LR, et al. Among authors: cuccaro ml. Alzheimers Dement. 2024 Dec 23. doi: 10.1002/alz.14356. Online ahead of print. Alzheimers Dement. 2024. PMID: 39711484
Cerebral amyloid angiopathy impacts neurofibrillary tangle burden and cognition.
Godrich D, Pasteris J, Martin ER, Rundek T, Schellenberg G, Foroud T, Vance JM, Pericak-Vance MA, Cuccaro ML, Scott WK, Kukull W, Montine TJ, Beecham GW. Godrich D, et al. Among authors: cuccaro ml. Brain Commun. 2024 Nov 22;6(6):fcae369. doi: 10.1093/braincomms/fcae369. eCollection 2024. Brain Commun. 2024. PMID: 39584156 Free PMC article.
African origin haplotype protective for Alzheimer's disease in APOEε4 carriers: exploring potential mechanisms.
Bertholim-Nasciben L, Nuytemans K, Van Booven D, Rajabli F, Moura S, Ramirez AM, Dykxhoorn DM, Wang L, Scott WK, Davis DA, Vontell RT, McInerney KF, Cuccaro ML, Byrd GS, Haines JL, Gearing M, Adams LD, Pericak-Vance MA; ADSP; Young JI, Griswold AJ, Vance JM. Bertholim-Nasciben L, et al. Among authors: cuccaro ml. bioRxiv [Preprint]. 2024 Oct 27:2024.10.24.619909. doi: 10.1101/2024.10.24.619909. bioRxiv. 2024. PMID: 39484566 Free PMC article. Preprint.
Methylation Clocks Do Not Predict Age or Alzheimer's Disease Risk Across Genetically Admixed Individuals.
Cruz-González S, Gu E, Gomez L, Mews M, Vance JM, Cuccaro ML, Cornejo-Olivas MR, Feliciano-Astacio BE, Byrd GS, Haines JL, Pericak-Vance MA, Griswold AJ, Bush WS, Capra JA. Cruz-González S, et al. Among authors: cuccaro ml. bioRxiv [Preprint]. 2024 Oct 18:2024.10.16.618588. doi: 10.1101/2024.10.16.618588. bioRxiv. 2024. PMID: 39464059 Free PMC article. Preprint.
Amyloid-β predominant Alzheimer's disease neuropathologic change.
Kovacs GG, Katsumata Y, Wu X, Aung KZ, Fardo DW, Forrest SL; Alzheimer's Disease Genetics Consortium; Nelson PT. Kovacs GG, et al. Brain. 2024 Oct 17:awae325. doi: 10.1093/brain/awae325. Online ahead of print. Brain. 2024. PMID: 39417691
Genetic analysis of cognitive preservation in the midwestern Amish reveals a novel locus on chromosome 2.
Main LR, Song YE, Lynn A, Laux RA, Miskimen KL, Osterman MD, Cuccaro ML, Ogrocki PK, Lerner AJ, Vance JM, Fuzzell D, Fuzzell SL, Hochstetler SD, Dorfsman DA, Caywood LJ, Prough MB, Adams LD, Clouse JE, Herington SD, Scott WK, Pericak-Vance MA, Haines JL. Main LR, et al. Among authors: cuccaro ml. Alzheimers Dement. 2024 Nov;20(11):7453-7464. doi: 10.1002/alz.14045. Epub 2024 Oct 8. Alzheimers Dement. 2024. PMID: 39376159 Free PMC article.
Genome-wide association analysis and admixture mapping in a Puerto Rican cohort supports an Alzheimer disease risk locus on chromosome 12.
Akgun B, Feliciano-Astacio BE, Hamilton-Nelson KL, Scott K, Rivero J, Adams LD, Sanchez JJ, Valladares GS, Tejada S, Bussies PL, Silva-Vergara C, Rodriguez VC, Mena PR, Celis K, Whitehead PG, Prough M, Kosanovic C, Van Booven DJ, Schmidt MA, Acosta H, Griswold AJ, Dalgard CL, McInerney KF, Beecham GW, Cuccaro ML, Vance JM, Pericak-Vance MA, Rajabli F. Akgun B, et al. Among authors: cuccaro ml. Front Aging Neurosci. 2024 Sep 4;16:1459796. doi: 10.3389/fnagi.2024.1459796. eCollection 2024. Front Aging Neurosci. 2024. PMID: 39295643 Free PMC article.
154 results