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m6A mRNA methylation in brown fat regulates systemic insulin sensitivity via an inter-organ prostaglandin signaling axis independent of UCP1.
Xiao L, De Jesus DF, Ju CW, Wei JB, Hu J, DiStefano-Forti A, Tsuji T, Cero C, Männistö V, Manninen SM, Wei S, Ijaduola O, Blüher M, Cypess AM, Pihlajamäki J, Tseng YH, He C, Kulkarni RN. Xiao L, et al. Among authors: hu j. Cell Metab. 2024 Oct 1;36(10):2207-2227.e9. doi: 10.1016/j.cmet.2024.08.006. Epub 2024 Sep 9. Cell Metab. 2024. PMID: 39255799
Ablation of TRIP-Br2, a regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance.
Liew CW, Boucher J, Cheong JK, Vernochet C, Koh HJ, Mallol C, Townsend K, Langin D, Kawamori D, Hu J, Tseng YH, Hellerstein MK, Farmer SR, Goodyear L, Doria A, Blüher M, Hsu SI, Kulkarni RN. Liew CW, et al. Among authors: hu j. Nat Med. 2013 Feb;19(2):217-26. doi: 10.1038/nm.3056. Epub 2013 Jan 6. Nat Med. 2013. PMID: 23291629 Free PMC article.
Redox regulation of m6A methyltransferase METTL3 in β-cells controls the innate immune response in type 1 diabetes.
De Jesus DF, Zhang Z, Brown NK, Li X, Xiao L, Hu J, Gaffrey MJ, Fogarty G, Kahraman S, Wei J, Basile G, Rana TM, Mathews C, Powers AC, Parent AV, Atkinson MA, Dhe-Paganon S, Eizirik DL, Qian WJ, He C, Kulkarni RN. De Jesus DF, et al. Among authors: hu j. Nat Cell Biol. 2024 Mar;26(3):421-437. doi: 10.1038/s41556-024-01368-0. Epub 2024 Feb 26. Nat Cell Biol. 2024. PMID: 38409327 Free PMC article.
SerpinB1 Promotes Pancreatic β Cell Proliferation.
El Ouaamari A, Dirice E, Gedeon N, Hu J, Zhou JY, Shirakawa J, Hou L, Goodman J, Karampelias C, Qiang G, Boucher J, Martinez R, Gritsenko MA, De Jesus DF, Kahraman S, Bhatt S, Smith RD, Beer HD, Jungtrakoon P, Gong Y, Goldfine AB, Liew CW, Doria A, Andersson O, Qian WJ, Remold-O'Donnell E, Kulkarni RN. El Ouaamari A, et al. Among authors: hu j. Cell Metab. 2016 Jan 12;23(1):194-205. doi: 10.1016/j.cmet.2015.12.001. Epub 2015 Dec 15. Cell Metab. 2016. PMID: 26701651 Free PMC article.
37,955 results
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